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Garlic, green tea and turmeric extracts-mediated green synthesis of silver nanoparticles: Phytochemical, antioxidant and in vitro cytotoxicity studies.
J Photochem Photobiol B. 2018 Mar; 180:243-252.JP

Abstract

Phyto-synthesis of silver nanoparticles (AgNPs) was achieved using aqueous garlic, green tea and turmeric extracts, and characterized by different spectroscopic techniques. Phytochemical analysis revealed the presence of rich amount of biochemicals in these extracts, which serve as reducing and capping agents for converting silver nitrate into AgNPs. FT IR spectroscopy confirmed the role of biomolecules in the bioreduction and efficient stabilization of AgNPs. UV-Vis DRS spectra showed a band around 450 nm characteristics of AgNPs. XRD patterns revealed the crystalline nature of the synthesized AgNPs with fcc structure. SEM and TEM analysis revealed the spherical shape of the synthesized AgNPs with an average particle size of 8 nm. EDX analysis confirmed the purity of the synthesized AgNPs with a strong signal at 3.2 keV. The antioxidant activity was assessed by ABTS, DPPH, p-NDA, H2O2 and DMSO scavenging assays, in which the AgNPs synthesized using green method showed remarkable activity with respect to the standard antioxidants ascorbic acid and rutin. In vitro cytotoxicity activity was tested on four cancer cell lines such as human breast adenocarcinoma (MCF-7), cervical (HeLa), epithelioma (Hep-2) and lung (A549) along with one normal human dermal fibroblasts (NHDF) cell line. The AgNPs synthesized using turmeric extract exhibits excellent antioxidant and cytotoxicity activity compared to that synthesized using other extracts.

Authors+Show Affiliations

Post-Graduate and Research Department of Chemistry, The New College (Autonomous), Chennai 600 014, India.Post-Graduate and Research Department of Chemistry, The New College (Autonomous), Chennai 600 014, India.Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Tiruchengode 637 205, India.Post-Graduate and Research Department of Chemistry, The New College (Autonomous), Chennai 600 014, India. Electronic address: akrahmanjkr@thenewcollege.in.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29476965

Citation

Arumai Selvan, D, et al. "Garlic, Green Tea and Turmeric Extracts-mediated Green Synthesis of Silver Nanoparticles: Phytochemical, Antioxidant and in Vitro Cytotoxicity Studies." Journal of Photochemistry and Photobiology. B, Biology, vol. 180, 2018, pp. 243-252.
Arumai Selvan D, Mahendiran D, Senthil Kumar R, et al. Garlic, green tea and turmeric extracts-mediated green synthesis of silver nanoparticles: Phytochemical, antioxidant and in vitro cytotoxicity studies. J Photochem Photobiol B. 2018;180:243-252.
Arumai Selvan, D., Mahendiran, D., Senthil Kumar, R., & Kalilur Rahiman, A. (2018). Garlic, green tea and turmeric extracts-mediated green synthesis of silver nanoparticles: Phytochemical, antioxidant and in vitro cytotoxicity studies. Journal of Photochemistry and Photobiology. B, Biology, 180, 243-252. https://doi.org/10.1016/j.jphotobiol.2018.02.014
Arumai Selvan D, et al. Garlic, Green Tea and Turmeric Extracts-mediated Green Synthesis of Silver Nanoparticles: Phytochemical, Antioxidant and in Vitro Cytotoxicity Studies. J Photochem Photobiol B. 2018;180:243-252. PubMed PMID: 29476965.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Garlic, green tea and turmeric extracts-mediated green synthesis of silver nanoparticles: Phytochemical, antioxidant and in vitro cytotoxicity studies. AU - Arumai Selvan,D, AU - Mahendiran,D, AU - Senthil Kumar,R, AU - Kalilur Rahiman,A, Y1 - 2018/02/14/ PY - 2017/10/23/received PY - 2017/12/22/revised PY - 2018/02/12/accepted PY - 2018/2/25/pubmed PY - 2018/4/7/medline PY - 2018/2/25/entrez KW - Antioxidant activity KW - Apoptosis KW - Garlic extract KW - Green tea extract KW - Turmeric extract SP - 243 EP - 252 JF - Journal of photochemistry and photobiology. B, Biology JO - J Photochem Photobiol B VL - 180 N2 - Phyto-synthesis of silver nanoparticles (AgNPs) was achieved using aqueous garlic, green tea and turmeric extracts, and characterized by different spectroscopic techniques. Phytochemical analysis revealed the presence of rich amount of biochemicals in these extracts, which serve as reducing and capping agents for converting silver nitrate into AgNPs. FT IR spectroscopy confirmed the role of biomolecules in the bioreduction and efficient stabilization of AgNPs. UV-Vis DRS spectra showed a band around 450 nm characteristics of AgNPs. XRD patterns revealed the crystalline nature of the synthesized AgNPs with fcc structure. SEM and TEM analysis revealed the spherical shape of the synthesized AgNPs with an average particle size of 8 nm. EDX analysis confirmed the purity of the synthesized AgNPs with a strong signal at 3.2 keV. The antioxidant activity was assessed by ABTS, DPPH, p-NDA, H2O2 and DMSO scavenging assays, in which the AgNPs synthesized using green method showed remarkable activity with respect to the standard antioxidants ascorbic acid and rutin. In vitro cytotoxicity activity was tested on four cancer cell lines such as human breast adenocarcinoma (MCF-7), cervical (HeLa), epithelioma (Hep-2) and lung (A549) along with one normal human dermal fibroblasts (NHDF) cell line. The AgNPs synthesized using turmeric extract exhibits excellent antioxidant and cytotoxicity activity compared to that synthesized using other extracts. SN - 1873-2682 UR - https://www.unboundmedicine.com/medline/citation/29476965/Garlic_green_tea_and_turmeric_extracts_mediated_green_synthesis_of_silver_nanoparticles:_Phytochemical_antioxidant_and_in_vitro_cytotoxicity_studies_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1011-1344(17)31311-8 DB - PRIME DP - Unbound Medicine ER -