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A Young Boy with Persistent Nodules and Hoarseness: A Rare Presentation of Nodular Secondary Syphilis.
J Coll Physicians Surg Pak. 2018 Mar; 28(3):S37-S38.JC

Abstract

Syphilis is a venereal disease caused by treponema pallidum, historically known as "great mimicker" because of its variable presentations. Secondary syphilis usually presents with maculopapular or papulosquamous rash. Rare manifestations include papulonodular, annular and lichenoid lesions. Nodules are usually found in benign tertiary syphilis. We present a case of a young boy who presented with five months' history of nodular skin lesions and hoarseness of voice. Venereal disease research laboratory (VDRL) was initially negative owing to prozone phenomenon. However, histopathology was confirmatory and he responded to benzathine penicillin. We present this case because of rare clinical presentation with persistent nodular lesions, unusual age group, and negative initial VDRL test.

Authors+Show Affiliations

Department of Dermatology, Jinnah Postgraduate Medical Centre (JPMC), Karachi.Department of Dermatology, Bahria University Medical And Dental College (BUMDC) and PNS Shifa, Karachi.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29482701

Citation

Ghafoor, Rabia, and Muhammad Irfan Anwar. "A Young Boy With Persistent Nodules and Hoarseness: a Rare Presentation of Nodular Secondary Syphilis." Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, vol. 28, no. 3, 2018, pp. S37-S38.
Ghafoor R, Anwar MI. A Young Boy with Persistent Nodules and Hoarseness: A Rare Presentation of Nodular Secondary Syphilis. J Coll Physicians Surg Pak. 2018;28(3):S37-S38.
Ghafoor, R., & Anwar, M. I. (2018). A Young Boy with Persistent Nodules and Hoarseness: A Rare Presentation of Nodular Secondary Syphilis. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 28(3), S37-S38. https://doi.org/10.29271/jcpsp.2018.03.S37
Ghafoor R, Anwar MI. A Young Boy With Persistent Nodules and Hoarseness: a Rare Presentation of Nodular Secondary Syphilis. J Coll Physicians Surg Pak. 2018;28(3):S37-S38. PubMed PMID: 29482701.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A Young Boy with Persistent Nodules and Hoarseness: A Rare Presentation of Nodular Secondary Syphilis. AU - Ghafoor,Rabia, AU - Anwar,Muhammad Irfan, PY - 2016/06/09/received PY - 2017/10/23/accepted PY - 2018/2/28/entrez PY - 2018/2/28/pubmed PY - 2018/9/1/medline SP - S37 EP - S38 JF - Journal of the College of Physicians and Surgeons--Pakistan : JCPSP JO - J Coll Physicians Surg Pak VL - 28 IS - 3 N2 - Syphilis is a venereal disease caused by treponema pallidum, historically known as "great mimicker" because of its variable presentations. Secondary syphilis usually presents with maculopapular or papulosquamous rash. Rare manifestations include papulonodular, annular and lichenoid lesions. Nodules are usually found in benign tertiary syphilis. We present a case of a young boy who presented with five months' history of nodular skin lesions and hoarseness of voice. Venereal disease research laboratory (VDRL) was initially negative owing to prozone phenomenon. However, histopathology was confirmatory and he responded to benzathine penicillin. We present this case because of rare clinical presentation with persistent nodular lesions, unusual age group, and negative initial VDRL test. SN - 1681-7168 UR - https://www.unboundmedicine.com/medline/citation/29482701/A_Young_Boy_with_Persistent_Nodules_and_Hoarseness:_A_Rare_Presentation_of_Nodular_Secondary_Syphilis_ L2 - https://medlineplus.gov/syphilis.html DB - PRIME DP - Unbound Medicine ER -