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Globalization and the Changing Epidemiology of Hepatitis A Virus.
Cold Spring Harb Perspect Med. 2018 10 01; 8(10)CS

Abstract

Increased economic interdependence, social integration, and other aspects of globalization are contributing to significant changes in hepatitis A epidemiology. Globally, the incidence of hepatitis A virus (HAV) infection is decreasing, the age at midpoint of population immunity (AMPI) is increasing, and the proportion of symptomatic cases is increasing as the average age at infection increases. In low-income countries, HAV remains endemic but improved water and sanitation systems are reducing transmission rates among young children. In high-income countries, most adults remain susceptible to HAV and foodborne outbreaks are becoming more frequent. Middle-income countries have diverse epidemiological profiles, and they play important roles in the global spread of HAV through international trade and travel. Future changes in the epidemiology of hepatitis A will be heavily influenced by globalization processes.

Authors+Show Affiliations

College of Health and Human Services, George Mason University, Fairfax, Virginia 22030.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29500305

Citation

Jacobsen, Kathryn H.. "Globalization and the Changing Epidemiology of Hepatitis a Virus." Cold Spring Harbor Perspectives in Medicine, vol. 8, no. 10, 2018.
Jacobsen KH. Globalization and the Changing Epidemiology of Hepatitis A Virus. Cold Spring Harb Perspect Med. 2018;8(10).
Jacobsen, K. H. (2018). Globalization and the Changing Epidemiology of Hepatitis A Virus. Cold Spring Harbor Perspectives in Medicine, 8(10). https://doi.org/10.1101/cshperspect.a031716
Jacobsen KH. Globalization and the Changing Epidemiology of Hepatitis a Virus. Cold Spring Harb Perspect Med. 2018 10 1;8(10) PubMed PMID: 29500305.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Globalization and the Changing Epidemiology of Hepatitis A Virus. A1 - Jacobsen,Kathryn H, Y1 - 2018/10/01/ PY - 2018/3/4/pubmed PY - 2019/12/18/medline PY - 2018/3/4/entrez JF - Cold Spring Harbor perspectives in medicine JO - Cold Spring Harb Perspect Med VL - 8 IS - 10 N2 - Increased economic interdependence, social integration, and other aspects of globalization are contributing to significant changes in hepatitis A epidemiology. Globally, the incidence of hepatitis A virus (HAV) infection is decreasing, the age at midpoint of population immunity (AMPI) is increasing, and the proportion of symptomatic cases is increasing as the average age at infection increases. In low-income countries, HAV remains endemic but improved water and sanitation systems are reducing transmission rates among young children. In high-income countries, most adults remain susceptible to HAV and foodborne outbreaks are becoming more frequent. Middle-income countries have diverse epidemiological profiles, and they play important roles in the global spread of HAV through international trade and travel. Future changes in the epidemiology of hepatitis A will be heavily influenced by globalization processes. SN - 2157-1422 UR - https://www.unboundmedicine.com/medline/citation/29500305/full_citation L2 - http://perspectivesinmedicine.cshlp.org/cgi/pmidlookup?view=long&pmid=29500305 DB - PRIME DP - Unbound Medicine ER -
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