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Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016.
MMWR Morb Mortal Wkly Rep. 2018 Mar 09; 67(9):265-269.MM

Abstract

Zika virus is a flavivirus primarily transmitted to humans by Aedes aegypti mosquitoes (1). Zika virus infections also have been documented through intrauterine transmission resulting in congenital infection; intrapartum transmission from a viremic mother to her newborn; sexual transmission; blood transfusion; and laboratory exposure (1-3). Most Zika virus infections are asymptomatic or result in mild clinical illness, characterized by acute onset of fever, maculopapular rash, arthralgia, or nonpurulent conjunctivitis; Guillain-Barré syndrome, meningoencephalitis, and severe thrombocytopenia rarely have been associated with Zika virus infection (1). However, congenital Zika virus infection can result in fetal loss, microcephaly, and other birth defects (1,2). In 2016, a total of 5,168 noncongenital Zika virus disease cases were reported from U.S. states and the District of Columbia. Most cases (4,897, 95%) were in travelers returning from Zika virus-affected areas. A total of 224 (4%) cases were acquired through presumed local mosquitoborne transmission, and 47 (1%) were acquired by other routes. It is important that providers in the United States continue to test symptomatic patients who live in or recently traveled to areas with ongoing Zika virus transmission or had unprotected sex with someone who lives in or traveled to those areas. All pregnant women and their partners should take measures to prevent Zika virus infection during pregnancy. A list of affected areas and specific recommendations on how to prevent Zika virus infection during pregnancy are available at https://www.cdc.gov/pregnancy/zika/protect-yourself.html.

Links

PMC Free PDF

Authors

Hall V
No affiliation info available
Walker WL
No affiliation info available
Lindsey NP
No affiliation info available
Lehman JA
No affiliation info available
Kolsin J
No affiliation info available
Landry K
No affiliation info available
Rabe IB
No affiliation info available
Hills SL
No affiliation info available
Fischer M
No affiliation info available
Staples JE
No affiliation info available
Gould CV
No affiliation info available
Martin SW
No affiliation info available

MeSH

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolDistrict of ColumbiaFemaleHumansInfantMaleMiddle AgedPregnancyUnited StatesYoung AdultZika Virus Infection

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29518067

Citation

Hall, Victoria, et al. "Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016." MMWR. Morbidity and Mortality Weekly Report, vol. 67, no. 9, 2018, pp. 265-269.
Hall V, Walker WL, Lindsey NP, et al. Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016. MMWR Morb Mortal Wkly Rep. 2018;67(9):265-269.
Hall, V., Walker, W. L., Lindsey, N. P., Lehman, J. A., Kolsin, J., Landry, K., Rabe, I. B., Hills, S. L., Fischer, M., Staples, J. E., Gould, C. V., & Martin, S. W. (2018). Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016. MMWR. Morbidity and Mortality Weekly Report, 67(9), 265-269. https://doi.org/10.15585/mmwr.mm6709a1
Hall V, et al. Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016. MMWR Morb Mortal Wkly Rep. 2018 Mar 9;67(9):265-269. PubMed PMID: 29518067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Update: Noncongenital Zika Virus Disease Cases - 50 U.S. States and the District of Columbia, 2016. AU - Hall,Victoria, AU - Walker,William L, AU - Lindsey,Nicole P, AU - Lehman,Jennifer A, AU - Kolsin,Jonathan, AU - Landry,Kimberly, AU - Rabe,Ingrid B, AU - Hills,Susan L, AU - Fischer,Marc, AU - Staples,J Erin, AU - Gould,Carolyn V, AU - Martin,Stacey W, Y1 - 2018/03/09/ PY - 2018/3/9/entrez PY - 2018/3/9/pubmed PY - 2018/3/13/medline SP - 265 EP - 269 JF - MMWR. Morbidity and mortality weekly report JO - MMWR Morb Mortal Wkly Rep VL - 67 IS - 9 N2 - Zika virus is a flavivirus primarily transmitted to humans by Aedes aegypti mosquitoes (1). Zika virus infections also have been documented through intrauterine transmission resulting in congenital infection; intrapartum transmission from a viremic mother to her newborn; sexual transmission; blood transfusion; and laboratory exposure (1-3). Most Zika virus infections are asymptomatic or result in mild clinical illness, characterized by acute onset of fever, maculopapular rash, arthralgia, or nonpurulent conjunctivitis; Guillain-Barré syndrome, meningoencephalitis, and severe thrombocytopenia rarely have been associated with Zika virus infection (1). However, congenital Zika virus infection can result in fetal loss, microcephaly, and other birth defects (1,2). In 2016, a total of 5,168 noncongenital Zika virus disease cases were reported from U.S. states and the District of Columbia. Most cases (4,897, 95%) were in travelers returning from Zika virus-affected areas. A total of 224 (4%) cases were acquired through presumed local mosquitoborne transmission, and 47 (1%) were acquired by other routes. It is important that providers in the United States continue to test symptomatic patients who live in or recently traveled to areas with ongoing Zika virus transmission or had unprotected sex with someone who lives in or traveled to those areas. All pregnant women and their partners should take measures to prevent Zika virus infection during pregnancy. A list of affected areas and specific recommendations on how to prevent Zika virus infection during pregnancy are available at https://www.cdc.gov/pregnancy/zika/protect-yourself.html. SN - 1545-861X UR - https://www.unboundmedicine.com/medline/citation/29518067/full_citation DB - PRIME DP - Unbound Medicine ER -