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Graphene blended with SnO2 and Pd-Pt nanocages for sensitive non-enzymatic electrochemical detection of H2O2 released from living cells.
Anal Chim Acta. 2018 Jul 19; 1014:10-18.AC

Abstract

This paper described a novel, facile and nonenzymatic electrochemical biosensor to detect hydrogen peroxide (H2O2). The sensor was fabricated based on Pd-Pt nanocages and SnO2/graphene nanosheets modified electrode (PdPt NCs@SGN/GCE). The electrochemical behavior of PdPt NCs@SGN/GCE exhibited excellent catalytic activity toward H2O2 with fast response, high selectivity, superior sensitivity, low detection limit of 0.3 μM and large linear range from 1 μM to 300 μM. Under these obvious advantages, the constructed biosensor provided to be reliable for determination of H2O2 secreted from human cervical cancer cells (Hela cells). Hence, the proposed biosensor is a promising candidate for detection of H2O2 in situ released from living cells in clinical diagnostics.

Authors+Show Affiliations

College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: yebx@zzu.edu.cn.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29523247

Citation

Fu, Yamin, et al. "Graphene Blended With SnO2 and Pd-Pt Nanocages for Sensitive Non-enzymatic Electrochemical Detection of H2O2 Released From Living Cells." Analytica Chimica Acta, vol. 1014, 2018, pp. 10-18.
Fu Y, Huang D, Li C, et al. Graphene blended with SnO2 and Pd-Pt nanocages for sensitive non-enzymatic electrochemical detection of H2O2 released from living cells. Anal Chim Acta. 2018;1014:10-18.
Fu, Y., Huang, D., Li, C., Zou, L., & Ye, B. (2018). Graphene blended with SnO2 and Pd-Pt nanocages for sensitive non-enzymatic electrochemical detection of H2O2 released from living cells. Analytica Chimica Acta, 1014, 10-18. https://doi.org/10.1016/j.aca.2018.01.067
Fu Y, et al. Graphene Blended With SnO2 and Pd-Pt Nanocages for Sensitive Non-enzymatic Electrochemical Detection of H2O2 Released From Living Cells. Anal Chim Acta. 2018 Jul 19;1014:10-18. PubMed PMID: 29523247.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Graphene blended with SnO2 and Pd-Pt nanocages for sensitive non-enzymatic electrochemical detection of H2O2 released from living cells. AU - Fu,Yamin, AU - Huang,Di, AU - Li,Congming, AU - Zou,Lina, AU - Ye,Baoxian, Y1 - 2018/02/07/ PY - 2017/11/06/received PY - 2018/01/23/revised PY - 2018/01/25/accepted PY - 2018/3/11/entrez PY - 2018/3/11/pubmed PY - 2018/8/15/medline KW - Electrochemistry KW - Hela cell KW - Hydrogen peroxide KW - Pd-Pt nanocages KW - SnO(2) SP - 10 EP - 18 JF - Analytica chimica acta JO - Anal. Chim. Acta VL - 1014 N2 - This paper described a novel, facile and nonenzymatic electrochemical biosensor to detect hydrogen peroxide (H2O2). The sensor was fabricated based on Pd-Pt nanocages and SnO2/graphene nanosheets modified electrode (PdPt NCs@SGN/GCE). The electrochemical behavior of PdPt NCs@SGN/GCE exhibited excellent catalytic activity toward H2O2 with fast response, high selectivity, superior sensitivity, low detection limit of 0.3 μM and large linear range from 1 μM to 300 μM. Under these obvious advantages, the constructed biosensor provided to be reliable for determination of H2O2 secreted from human cervical cancer cells (Hela cells). Hence, the proposed biosensor is a promising candidate for detection of H2O2 in situ released from living cells in clinical diagnostics. SN - 1873-4324 UR - https://www.unboundmedicine.com/medline/citation/29523247/Graphene_blended_with_SnO2_and_Pd_Pt_nanocages_for_sensitive_non_enzymatic_electrochemical_detection_of_H2O2_released_from_living_cells_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003-2670(18)30172-7 DB - PRIME DP - Unbound Medicine ER -