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[Endocrine profile of patients with post-pill amenorrhea].

Abstract

"Post-pill amenorrhea" is still a much-debated subject in gynecological endocrinology. The authors therefore studied the reproductive history and endocrinological parameters of 145 patients with the presumptive diagnosis of post-pill amenorrhea, seen in their department during the last two years; 166 cases of secondary amenorrhea served as a control group. The incidence of late menarche (20%), previous oligomenorrhea, and elevated androgen serum levels was high in both groups. There were no significant differences between the two collectives. These findings suggest that although oral contraceptives may have an unfavorable influence on the menstrual cycle, there is no causal relationship between such agents and the development of secondary amenorrhea. It seems that in many cases of presumptive post-pill amenorrhea the common condition of juvenile hyperandrogenemic ovarian insufficiency might be the underlying problem.

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  • Authors

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    Source

    Geburtshilfe und Frauenheilkunde 47:6 1987 Jun pg 414-6

    MeSH

    Adolescent
    Adult
    Age Factors
    Amenorrhea
    Androgens
    Androstenedione
    Contraceptives, Oral
    Dehydroepiandrosterone
    Female
    Follicle Stimulating Hormone
    Gonadotropins, Pituitary
    Humans
    Luteinizing Hormone
    Menarche
    Prolactin
    Testosterone

    Pub Type(s)

    Comparative Study
    English Abstract
    Journal Article

    Language

    ger

    PubMed ID

    2957264

    Citation

    Vytiska-Binstorfer, E, et al. "[Endocrine Profile of Patients With Post-pill Amenorrhea]." Geburtshilfe Und Frauenheilkunde, vol. 47, no. 6, 1987, pp. 414-6.
    Vytiska-Binstorfer E, Huber JC, Spona J, et al. [Endocrine profile of patients with post-pill amenorrhea]. Geburtshilfe Frauenheilkd. 1987;47(6):414-6.
    Vytiska-Binstorfer, E., Huber, J. C., Spona, J., & Gitsch, E. (1987). [Endocrine profile of patients with post-pill amenorrhea]. Geburtshilfe Und Frauenheilkunde, 47(6), pp. 414-6.
    Vytiska-Binstorfer E, et al. [Endocrine Profile of Patients With Post-pill Amenorrhea]. Geburtshilfe Frauenheilkd. 1987;47(6):414-6. PubMed PMID: 2957264.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - [Endocrine profile of patients with post-pill amenorrhea]. AU - Vytiska-Binstorfer,E, AU - Huber,J C, AU - Spona,J, AU - Gitsch,E, PY - 1987/6/1/pubmed PY - 1987/6/1/medline PY - 1987/6/1/entrez SP - 414 EP - 6 JF - Geburtshilfe und Frauenheilkunde JO - Geburtshilfe Frauenheilkd VL - 47 IS - 6 N2 - "Post-pill amenorrhea" is still a much-debated subject in gynecological endocrinology. The authors therefore studied the reproductive history and endocrinological parameters of 145 patients with the presumptive diagnosis of post-pill amenorrhea, seen in their department during the last two years; 166 cases of secondary amenorrhea served as a control group. The incidence of late menarche (20%), previous oligomenorrhea, and elevated androgen serum levels was high in both groups. There were no significant differences between the two collectives. These findings suggest that although oral contraceptives may have an unfavorable influence on the menstrual cycle, there is no causal relationship between such agents and the development of secondary amenorrhea. It seems that in many cases of presumptive post-pill amenorrhea the common condition of juvenile hyperandrogenemic ovarian insufficiency might be the underlying problem. SN - 0016-5751 UR - https://www.unboundmedicine.com/medline/citation/2957264/[Endocrine_profile_of_patients_with_post_pill_amenorrhea]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1036147 DB - PRIME DP - Unbound Medicine ER -