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Urinary bisphenol analogues and triclosan in children from south China and implications for human exposure.
Environ Pollut. 2018 Jul; 238:299-305.EP

Abstract

Bisphenols and triclosan (TCS) are widely used in consumer products. However, knowledge on human exposure to these anthropogenic chemicals has remained limited in China, especially for children. In this study, concentrations of seven bisphenols and TCS were determined in 283 urine samples collected from South China children aged between 3 and 11 years old. Bisphenol A (BPA), bisphenol S (BPS) and TCS were frequently detected in urine samples, with a detection rate of 93%, 89%, and 95%, respectively. Urinary concentrations of Σ7BPs (the sum concentrations of the seven bisphenols) ranged from 0.43 to 31.5 μg/L, with a median value of 0.91 μg/L, while TCS concentrations ranged from < limit of quantification to 21.9 μg/L (median: 0.21 μg/L). BPA was the predominant analogue (median: 0.35 μg/L), accounting for 49.8% of Σ7BPs. The urinary BPA concentrations in children from Guangzhou were significantly greater than those from Shenzhen. Correlation analysis suggested that multiple exposure sources to South China children likely existed for BPA, BPS, and TCS. Age, but not gender, was negatively associated with urinary residues of BPA and BPS (p < 0.05) and positively with TCS concentrations (p < 0.05). The estimated daily intake of Σ7BPs (23.9 ng/kg bw/day) or TCS (5.63 ng/kg bw/day) was below the tolerant reference dose of BPA, indicating no considerable health hazard to South China children.

Authors+Show Affiliations

School of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.School of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.School of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China; Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.School of Life Science, South China Normal University, Guangzhou, 510631, China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 200444, China.Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China. Electronic address: lushaoyou2005@163.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29573712

Citation

Chen, Yi, et al. "Urinary Bisphenol Analogues and Triclosan in Children From South China and Implications for Human Exposure." Environmental Pollution (Barking, Essex : 1987), vol. 238, 2018, pp. 299-305.
Chen Y, Fang J, Ren L, et al. Urinary bisphenol analogues and triclosan in children from south China and implications for human exposure. Environ Pollut. 2018;238:299-305.
Chen, Y., Fang, J., Ren, L., Fan, R., Zhang, J., Liu, G., Zhou, L., Chen, D., Yu, Y., & Lu, S. (2018). Urinary bisphenol analogues and triclosan in children from south China and implications for human exposure. Environmental Pollution (Barking, Essex : 1987), 238, 299-305. https://doi.org/10.1016/j.envpol.2018.03.031
Chen Y, et al. Urinary Bisphenol Analogues and Triclosan in Children From South China and Implications for Human Exposure. Environ Pollut. 2018;238:299-305. PubMed PMID: 29573712.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Urinary bisphenol analogues and triclosan in children from south China and implications for human exposure. AU - Chen,Yi, AU - Fang,Jianzhang, AU - Ren,Lu, AU - Fan,Ruifang, AU - Zhang,Jianqing, AU - Liu,Guihua, AU - Zhou,Li, AU - Chen,Dingyan, AU - Yu,Yingxin, AU - Lu,Shaoyou, Y1 - 2018/03/22/ PY - 2017/09/27/received PY - 2018/03/05/revised PY - 2018/03/11/accepted PY - 2018/3/25/pubmed PY - 2018/7/27/medline PY - 2018/3/25/entrez KW - Bisphenol analogues KW - Children KW - Estimated daily intake KW - South China KW - Triclosan KW - Urine SP - 299 EP - 305 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ. Pollut. VL - 238 N2 - Bisphenols and triclosan (TCS) are widely used in consumer products. However, knowledge on human exposure to these anthropogenic chemicals has remained limited in China, especially for children. In this study, concentrations of seven bisphenols and TCS were determined in 283 urine samples collected from South China children aged between 3 and 11 years old. Bisphenol A (BPA), bisphenol S (BPS) and TCS were frequently detected in urine samples, with a detection rate of 93%, 89%, and 95%, respectively. Urinary concentrations of Σ7BPs (the sum concentrations of the seven bisphenols) ranged from 0.43 to 31.5 μg/L, with a median value of 0.91 μg/L, while TCS concentrations ranged from < limit of quantification to 21.9 μg/L (median: 0.21 μg/L). BPA was the predominant analogue (median: 0.35 μg/L), accounting for 49.8% of Σ7BPs. The urinary BPA concentrations in children from Guangzhou were significantly greater than those from Shenzhen. Correlation analysis suggested that multiple exposure sources to South China children likely existed for BPA, BPS, and TCS. Age, but not gender, was negatively associated with urinary residues of BPA and BPS (p < 0.05) and positively with TCS concentrations (p < 0.05). The estimated daily intake of Σ7BPs (23.9 ng/kg bw/day) or TCS (5.63 ng/kg bw/day) was below the tolerant reference dose of BPA, indicating no considerable health hazard to South China children. SN - 1873-6424 UR - https://www.unboundmedicine.com/medline/citation/29573712/Urinary_bisphenol_analogues_and_triclosan_in_children_from_south_China_and_implications_for_human_exposure_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0269-7491(17)34039-3 DB - PRIME DP - Unbound Medicine ER -