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Germline Editing: Editors Cautionary.
Clin Ter. 2018 Mar-Apr; 169(2):e58-e59.CT

Abstract

This communication is regarding the recent editing of the genome of the human embryo with CRISPR/Cas9 which generated a debate amongst the biological scientists around the world. Editing human germline genes may act as godsend in some serious genetic and other disorders as the genes related to these disorders can be replaced effectively. The scientists are in dilemma whether the human germline gene modification is a boon or bane for the human society. Though editing human germline genes may be an answer to many serious genetic disorders however; it may have unpredictable effects on future generations. The ethical issues regarding the germline editing need further discussion which may have implications on human race and on-going human evolution. Thus, the researchers need to be doubly cautious and some stringent regulations should be framed regarding the various aspects of germ line gene modifications and any potential conflict with nature for future outcome.

Authors+Show Affiliations

Associate Professor and Chair, Department of Anthropology, Panjab University, Sector-14, Chandigarh, India.Associate Professor - Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, Jodhpur, India.Research Scholar - Department of Anthropology, Panjab University, Sector-14, Chandigarh, India.Research Scholar - Department of Anthropology, Panjab University, Sector-14, Chandigarh, India.Professor - Biotechnology Department, University Institute of Engineering & Technology, Panjab University, Chandigarh, India.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29595865

Citation

Krishan, K, et al. "Germline Editing: Editors Cautionary." La Clinica Terapeutica, vol. 169, no. 2, 2018, pp. e58-e59.
Krishan K, Kanchan T, Singh B, et al. Germline Editing: Editors Cautionary. Clin Ter. 2018;169(2):e58-e59.
Krishan, K., Kanchan, T., Singh, B., Baryah, N., & Puri, S. (2018). Germline Editing: Editors Cautionary. La Clinica Terapeutica, 169(2), e58-e59. https://doi.org/10.7417/T.2018.2053
Krishan K, et al. Germline Editing: Editors Cautionary. Clin Ter. 2018 Mar-Apr;169(2):e58-e59. PubMed PMID: 29595865.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Germline Editing: Editors Cautionary. AU - Krishan,K, AU - Kanchan,T, AU - Singh,B, AU - Baryah,N, AU - Puri,S, PY - 2018/3/30/entrez PY - 2018/3/30/pubmed PY - 2018/7/31/medline KW - Ethics KW - Gene KW - Human germline editing KW - Human society SP - e58 EP - e59 JF - La Clinica terapeutica JO - Clin Ter VL - 169 IS - 2 N2 - This communication is regarding the recent editing of the genome of the human embryo with CRISPR/Cas9 which generated a debate amongst the biological scientists around the world. Editing human germline genes may act as godsend in some serious genetic and other disorders as the genes related to these disorders can be replaced effectively. The scientists are in dilemma whether the human germline gene modification is a boon or bane for the human society. Though editing human germline genes may be an answer to many serious genetic disorders however; it may have unpredictable effects on future generations. The ethical issues regarding the germline editing need further discussion which may have implications on human race and on-going human evolution. Thus, the researchers need to be doubly cautious and some stringent regulations should be framed regarding the various aspects of germ line gene modifications and any potential conflict with nature for future outcome. SN - 1972-6007 UR - https://www.unboundmedicine.com/medline/citation/29595865/Germline_Editing:_Editors_Cautionary_ L2 - http://www.clinicaterapeutica.it/ojs/index.php/ClinicaTerapeutica/article/view/144/80 DB - PRIME DP - Unbound Medicine ER -