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Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China.
BMC Public Health. 2018 04 03; 18(1):444.BP

Abstract

BACKGROUND

To investigative the association of triglycerides (TG) and total cholesterol (TC) concentrations with impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) in Chinese adults.

METHODS

The population-based cross-sectional diabetes survey was conducted in 2006 and 2009 in Qingdao, separately. 4400 participants (1 793 men and 2607 women) were include in current analysis. IFG/IGT was defined according to fasting plasma glucose (FPG) and/or 2 h post-load plasma glucose (2 h PG). Logistic regression models and areas under receiver operating characteristic curves (AUROC) were performed to estimate the associations between TG, TC levels and IFG/IGT.

RESULTS

Spearman analysis showed that serum TG and TC was independently and positively associated with FPG and 2 h PG. As compared with normoglycaemia, the odds ratio[(95% confidence intervals), OR(95%CI)] for IFG/IGT corresponding to hypertriglyceridemia (HTG) were 1.61 (1. 17, 2. 22) in men and 1.57(1.15, 2.14) in women for TG and accompany with Hypercholesterolemia (HTC) 1.56 (1.15, 2.13) and 1. 20 (0.93, 1.54) for TC, when adjusting for confounding factor. The AUROCs of TG, TC for IFG/IGT were relatively smaller (0.50 < AUROC< 0. 7) in both gender. The optimal cut-offs for TG and TC was 1.61, 4.91 in men and 1. 24, 5. 32 in women, respectively.

CONCLUSIONS

Evaluated TG in both gender and TC in men were independently associated with the present of the IFG/IGT, yet, could not be an authentic predictors of IFG/IGT in both men and women in current Chinese population.

Authors+Show Affiliations

School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, China. Qingdao Municipal Center for Disease Control and Prevention, Qingdao, 266033, China. Qingdao Institute of Preventive Medicine, Qingdao, 266033, China.School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, China. Qingdao Municipal Center for Disease Control and Prevention, Qingdao, 266033, China. Qingdao Institute of Preventive Medicine, Qingdao, 266033, China.School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, China. Key Laboratory of Food Safety Risk Assessment, Ministry of Health, China National Center for food safety Risk Assessment, Beijing, 100021, China.Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.Qingdao Municipal Center for Disease Control and Prevention, Qingdao, 266033, China. Qingdao Institute of Preventive Medicine, Qingdao, 266033, China.Department of Public Health, University of Helsinki, Helsinki, Finland.School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, China. magfood@126.com. Qingdao Municipal Center for Disease Control and Prevention, Qingdao, 266033, China. magfood@126.com.College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China. znablooch@yahoo.com.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

29615002

Citation

Cui, Jing, et al. "Triglycerides and Total Cholesterol Concentrations in Association With IFG/IGT in Chinese Adults in Qingdao, China." BMC Public Health, vol. 18, no. 1, 2018, p. 444.
Cui J, Sun J, Wang W, et al. Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China. BMC Public Health. 2018;18(1):444.
Cui, J., Sun, J., Wang, W., Yasmeen, N., Ke, M., Xin, H., Qiao, Q., Ma, A., & Baloch, Z. (2018). Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China. BMC Public Health, 18(1), 444. https://doi.org/10.1186/s12889-018-5286-z
Cui J, et al. Triglycerides and Total Cholesterol Concentrations in Association With IFG/IGT in Chinese Adults in Qingdao, China. BMC Public Health. 2018 04 3;18(1):444. PubMed PMID: 29615002.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Triglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China. AU - Cui,Jing, AU - Sun,Jianping, AU - Wang,Wei, AU - Yasmeen,Nafeesa, AU - Ke,Ma, AU - Xin,Hualei, AU - Qiao,Qing, AU - Ma,Aiguo, AU - Baloch,Zulqarnain, Y1 - 2018/04/03/ PY - 2017/10/16/received PY - 2018/03/08/accepted PY - 2018/4/5/entrez PY - 2018/4/5/pubmed PY - 2019/3/6/medline KW - Adult onset IFG/IGT KW - Total cholesterol KW - Triglycerides SP - 444 EP - 444 JF - BMC public health JO - BMC Public Health VL - 18 IS - 1 N2 - BACKGROUND: To investigative the association of triglycerides (TG) and total cholesterol (TC) concentrations with impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) in Chinese adults. METHODS: The population-based cross-sectional diabetes survey was conducted in 2006 and 2009 in Qingdao, separately. 4400 participants (1 793 men and 2607 women) were include in current analysis. IFG/IGT was defined according to fasting plasma glucose (FPG) and/or 2 h post-load plasma glucose (2 h PG). Logistic regression models and areas under receiver operating characteristic curves (AUROC) were performed to estimate the associations between TG, TC levels and IFG/IGT. RESULTS: Spearman analysis showed that serum TG and TC was independently and positively associated with FPG and 2 h PG. As compared with normoglycaemia, the odds ratio[(95% confidence intervals), OR(95%CI)] for IFG/IGT corresponding to hypertriglyceridemia (HTG) were 1.61 (1. 17, 2. 22) in men and 1.57(1.15, 2.14) in women for TG and accompany with Hypercholesterolemia (HTC) 1.56 (1.15, 2.13) and 1. 20 (0.93, 1.54) for TC, when adjusting for confounding factor. The AUROCs of TG, TC for IFG/IGT were relatively smaller (0.50 < AUROC< 0. 7) in both gender. The optimal cut-offs for TG and TC was 1.61, 4.91 in men and 1. 24, 5. 32 in women, respectively. CONCLUSIONS: Evaluated TG in both gender and TC in men were independently associated with the present of the IFG/IGT, yet, could not be an authentic predictors of IFG/IGT in both men and women in current Chinese population. SN - 1471-2458 UR - https://www.unboundmedicine.com/medline/citation/29615002/Triglycerides_and_total_cholesterol_concentrations_in_association_with_IFG/IGT_in_Chinese_adults_in_Qingdao_China_ L2 - https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-018-5286-z DB - PRIME DP - Unbound Medicine ER -