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Synthesis and characterization of chitosan modified polyurethane bio-nanocomposites with biomedical potential.
Int J Biol Macromol. 2018 Aug; 115:375-384.IJ

Abstract

A series of chitosan (CS) and montmorillonite (MMT) clay based polyurethane bio-nanocomposites were synthesized by step growth polymerization; reacting hydroxyl terminated polybutadiene (HTPB) and toluene diisocyanate (TDI) to improve thermal and antibacterial properties of polyurethane (PU). Five different PU samples were prepared by varying mole ratio of CS and 1,4-butane diol (from 0 to 2 mol). Structural studies of PUs through FTIR and 1H NMR spectroscopy confirmed the incorporation of CS into the polymer matrix. The scanning electron microscope (SEM) analysis confirmed well dispersion of MMT clay into the PU matrix. Thermogravimetric analysis (TGA) of PUs indicated significant enhancement of thermal stability of PU with addition of CS. Antibacterial properties of PUs were measured by disc diffusion method; showed excellent potential against the selected strains. On the whole, CS showed potential to improve the antibacterial and structural properties of PU significantly; which might be precursor for biological applications.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Javaid MA
Department of Chemistry, University of Agriculture, Faisalabad 38040, Pakistan.
Khera RA
Department of Chemistry, University of Agriculture, Faisalabad 38040, Pakistan.
Zia KM
Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan. Electronic address: drkmzia@gcuf.edu.pk.
Saito K
School of Chemistry, Monash University, Clayton, Victoria 3800, Australia.
Bhatti IA
Department of Chemistry, University of Agriculture, Faisalabad 38040, Pakistan.
Asghar M
Department of Biochemistry, University of Agriculture, Faisalabad 3804, Pakistan.

MeSH

Anti-Bacterial AgentsBacteriaChemistry Techniques, SyntheticChitosanNanocompositesPolyurethanes

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29627473

Citation

Javaid, Muhammad Asif, et al. "Synthesis and Characterization of Chitosan Modified Polyurethane Bio-nanocomposites With Biomedical Potential." International Journal of Biological Macromolecules, vol. 115, 2018, pp. 375-384.
Javaid MA, Khera RA, Zia KM, et al. Synthesis and characterization of chitosan modified polyurethane bio-nanocomposites with biomedical potential. Int J Biol Macromol. 2018;115:375-384.
Javaid, M. A., Khera, R. A., Zia, K. M., Saito, K., Bhatti, I. A., & Asghar, M. (2018). Synthesis and characterization of chitosan modified polyurethane bio-nanocomposites with biomedical potential. International Journal of Biological Macromolecules, 115, 375-384. https://doi.org/10.1016/j.ijbiomac.2018.04.013
Javaid MA, et al. Synthesis and Characterization of Chitosan Modified Polyurethane Bio-nanocomposites With Biomedical Potential. Int J Biol Macromol. 2018;115:375-384. PubMed PMID: 29627473.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis and characterization of chitosan modified polyurethane bio-nanocomposites with biomedical potential. AU - Javaid,Muhammad Asif, AU - Khera,Rasheed Ahmad, AU - Zia,Khalid Mahmood, AU - Saito,Kei, AU - Bhatti,Ijaz Ahmad, AU - Asghar,Muhammad, Y1 - 2018/04/05/ PY - 2018/02/25/received PY - 2018/03/24/revised PY - 2018/04/04/accepted PY - 2018/4/9/pubmed PY - 2018/10/17/medline PY - 2018/4/9/entrez KW - (1)H NMR KW - Bio-nanocomposites KW - Chitosan KW - Polyurethane SP - 375 EP - 384 JF - International journal of biological macromolecules JO - Int J Biol Macromol VL - 115 N2 - A series of chitosan (CS) and montmorillonite (MMT) clay based polyurethane bio-nanocomposites were synthesized by step growth polymerization; reacting hydroxyl terminated polybutadiene (HTPB) and toluene diisocyanate (TDI) to improve thermal and antibacterial properties of polyurethane (PU). Five different PU samples were prepared by varying mole ratio of CS and 1,4-butane diol (from 0 to 2 mol). Structural studies of PUs through FTIR and 1H NMR spectroscopy confirmed the incorporation of CS into the polymer matrix. The scanning electron microscope (SEM) analysis confirmed well dispersion of MMT clay into the PU matrix. Thermogravimetric analysis (TGA) of PUs indicated significant enhancement of thermal stability of PU with addition of CS. Antibacterial properties of PUs were measured by disc diffusion method; showed excellent potential against the selected strains. On the whole, CS showed potential to improve the antibacterial and structural properties of PU significantly; which might be precursor for biological applications. SN - 1879-0003 UR - https://www.unboundmedicine.com/medline/citation/29627473/Synthesis_and_characterization_of_chitosan_modified_polyurethane_bio_nanocomposites_with_biomedical_potential_ DB - PRIME DP - Unbound Medicine ER -