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[Routine semen parameters and sperm morphological index of infertile males with partial globozoospermia].
Zhonghua Nan Ke Xue 2017; 23(1):57-60ZN

Abstract

Objective

To investigate the routine semen parameters and sperm morphological indexes of the patients with partial globozoospermia (PGZ).

METHODS

We included in this study 100 infertile males with PGZ and another 180 non-PGZ infertile men as controls. According to the proportion of round-headed sperm (RHS) in the semen, we classified the PGZ males into five subgroups: 25%-40%, 41%-55%, 56%-70%, 71%-85%, and 86%-99% RHS. We obtained sperm concentration, total sperm motility, the percentage of progressively motile sperm, teratozoospermia index (TZI), and sperm deformity index (SDI) from the subjects and compared them among different groups.

RESULTS

Statistically significant differences were found between the PGZ patients and non-PGZ controls in total sperm motility ([35.76±24.88]% vs [62.03±10.20]%, P<0.01), the percentage of progressively motile sperm ([26.11±20.39]% vs [45.62±6.87]%, P<0.01), the percentage of morphologically normal sperm ([1.45±1.45]% vs [5.98±2.21]%, P<0.01), and SDI (1.33±0.11 vs 1.27±0.57, P<0.01), but not in age ([29.82±4.90] vs [30.33±3.59 ] yr, P>0.05), sperm concentration ([46.01±40.38] vs [54.00±25.15] ×106/ml, P>0.05), or TZI (1.35±0.11 vs 1.34±0.54, P>0.05). There were also significant differences among the five PGZ subgroups in total sperm motility, progressive sperm motility, normal sperm morphology, TZI, and SDI (P<0.01), but not in age or sperm concentration (P>0.05). Morphologically, the sperm head changed from heterogeneous to homogeneous with the increased proportion of round-headed sperm.

CONCLUSIONS

Different proportions of round-headed sperm are closely related to routine semen parameters and sperm morphological index in PGZ patients, which can help clinicians choose the proper assisted reproductive technology and predict the rate of fertilization for infertile males.

Authors+Show Affiliations

Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China.Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China.Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China.Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China.Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China.Center for Reproductive Medicine / National Research Center for Assisted Reproductive Technology and Reproductive Genetics / Key Laboratory for Reproductive Endocrinology of the Ministry of Education, Shandong University, Jinan, Shandong 250001, China..

Pub Type(s)

Journal Article

Language

chi

PubMed ID

29658238

Citation

Li, Ting, et al. "[Routine Semen Parameters and Sperm Morphological Index of Infertile Males With Partial Globozoospermia]." Zhonghua Nan Ke Xue = National Journal of Andrology, vol. 23, no. 1, 2017, pp. 57-60.
Li T, LIu W, Yang SJ, et al. [Routine semen parameters and sperm morphological index of infertile males with partial globozoospermia]. Zhonghua Nan Ke Xue. 2017;23(1):57-60.
Li, T., LIu, W., Yang, S. J., Zhang, C., Xie, N., Li, S. J., & Gao, X. (2017). [Routine semen parameters and sperm morphological index of infertile males with partial globozoospermia]. Zhonghua Nan Ke Xue = National Journal of Andrology, 23(1), pp. 57-60.
Li T, et al. [Routine Semen Parameters and Sperm Morphological Index of Infertile Males With Partial Globozoospermia]. Zhonghua Nan Ke Xue. 2017;23(1):57-60. PubMed PMID: 29658238.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Routine semen parameters and sperm morphological index of infertile males with partial globozoospermia]. AU - Li,Ting, AU - LIu,Wen, AU - Yang,Si-Jie, AU - Zhang,Chen, AU - Xie,Nan, AU - Li,Shi-Jun, AU - Gao,Xuan, PY - 2018/4/17/entrez PY - 2017/1/1/pubmed PY - 2018/8/16/medline KW - KW - partial globozoospermia KW - round-headed sperm KW - routine semen parameters KW - sperm deformity index KW - sperm morphology KW - teratozoospermia index SP - 57 EP - 60 JF - Zhonghua nan ke xue = National journal of andrology JO - Zhonghua Nan Ke Xue VL - 23 IS - 1 N2 - Objective: To investigate the routine semen parameters and sperm morphological indexes of the patients with partial globozoospermia (PGZ). METHODS: We included in this study 100 infertile males with PGZ and another 180 non-PGZ infertile men as controls. According to the proportion of round-headed sperm (RHS) in the semen, we classified the PGZ males into five subgroups: 25%-40%, 41%-55%, 56%-70%, 71%-85%, and 86%-99% RHS. We obtained sperm concentration, total sperm motility, the percentage of progressively motile sperm, teratozoospermia index (TZI), and sperm deformity index (SDI) from the subjects and compared them among different groups. RESULTS: Statistically significant differences were found between the PGZ patients and non-PGZ controls in total sperm motility ([35.76±24.88]% vs [62.03±10.20]%, P<0.01), the percentage of progressively motile sperm ([26.11±20.39]% vs [45.62±6.87]%, P<0.01), the percentage of morphologically normal sperm ([1.45±1.45]% vs [5.98±2.21]%, P<0.01), and SDI (1.33±0.11 vs 1.27±0.57, P<0.01), but not in age ([29.82±4.90] vs [30.33±3.59 ] yr, P>0.05), sperm concentration ([46.01±40.38] vs [54.00±25.15] ×106/ml, P>0.05), or TZI (1.35±0.11 vs 1.34±0.54, P>0.05). There were also significant differences among the five PGZ subgroups in total sperm motility, progressive sperm motility, normal sperm morphology, TZI, and SDI (P<0.01), but not in age or sperm concentration (P>0.05). Morphologically, the sperm head changed from heterogeneous to homogeneous with the increased proportion of round-headed sperm. CONCLUSIONS: Different proportions of round-headed sperm are closely related to routine semen parameters and sperm morphological index in PGZ patients, which can help clinicians choose the proper assisted reproductive technology and predict the rate of fertilization for infertile males. SN - 1009-3591 UR - https://www.unboundmedicine.com/medline/citation/29658238/[Routine_semen_parameters_and_sperm_morphological_index_of_infertile_males_with_partial_globozoospermia]_ L2 - https://medlineplus.gov/maleinfertility.html DB - PRIME DP - Unbound Medicine ER -