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[Research on quality standard of processed Cinnamomi Cortex decoction pieces containing volatile oil].
Zhongguo Zhong Yao Za Zhi. 2018 Mar; 43(5):885-890.ZZ

Abstract

To build the quality standard of processed Cinnamomi Cortex standard decoction and provide quality reference for Cinnamomi Cortex formula granules. Fourteen batches of Cinnamomi Cortex standard decoction pieces were prepared according to the preparation requirements for standard decoction of Chinese herbal medicine containing volatile oil. With cinnamaldehyde as the quantitative index, the transfer rate and extraction rate were calculated; pH value was determined and HPLC fingerprint analysis method was established. By the measurement of 14 batches of standard decoction, the transfer rate ranged from 25.0% to 68.4%; the extraction rate was at a range of 3.7% to 10.1% and pH was 3.72 to 5.48. Then the Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine (2012A) was used to analyze and compare the fingerprints. Four common peaks were determined and three were identified including coumarin (peak 1), cinnamic acid (peak 2) and cinnamaldehyde (peak 3). Moreover, the similarity was 1.0. This study established an HPLC fingerprint analysis method of processed Cinnamomi Cortex standard decoction. The method showed good precision, stability and repeatability in fingerprint analysis, with significance in identification.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine， Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

MeSH

Chromatography, High Pressure LiquidCinnamomum zeylanicumDrugs, Chinese HerbalOils, VolatileQuality Control

Pub Type(s)

Journal Article

Language

chi

PubMed ID

29676083

Citation

Deng, Zhe, et al. "[Research On Quality Standard of Processed Cinnamomi Cortex Decoction Pieces Containing Volatile Oil]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 43, no. 5, 2018, pp. 885-890.

Deng Z, Jiao MJ, Zhang J, et al. [Research on quality standard of processed Cinnamomi Cortex decoction pieces containing volatile oil]. Zhongguo Zhong Yao Za Zhi. 2018;43(5):885-890.

Deng, Z., Jiao, M. J., Zhang, J., Shen, L., Wang, S. H., Zhang, G. Y., Zhang, Q., Liu, A., & Wang, Y. S. (2018). [Research on quality standard of processed Cinnamomi Cortex decoction pieces containing volatile oil]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 43(5), 885-890. https://doi.org/10.19540/j.cnki.cjcmm.20180108.001

Deng Z, et al. [Research On Quality Standard of Processed Cinnamomi Cortex Decoction Pieces Containing Volatile Oil]. Zhongguo Zhong Yao Za Zhi. 2018;43(5):885-890. PubMed PMID: 29676083.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - [Research on quality standard of processed Cinnamomi Cortex decoction pieces containing volatile oil]. AU - Deng,Zhe, AU - Jiao,Meng-Jiao, AU - Zhang,Jun, AU - Shen,Li, AU - Wang,Shu-Hui, AU - Zhang,Guo-Yuan, AU - Zhang,Qing, AU - Liu,An, AU - Wang,Yue-Sheng, PY - 2017/10/15/received PY - 2018/4/21/entrez PY - 2018/4/21/pubmed PY - 2019/7/13/medline KW - formula granules KW - processed Cinnamomi Cortex decoction pieces KW - standard decoction KW - volatile oil SP - 885 EP - 890 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 43 IS - 5 N2 - To build the quality standard of processed Cinnamomi Cortex standard decoction and provide quality reference for Cinnamomi Cortex formula granules. Fourteen batches of Cinnamomi Cortex standard decoction pieces were prepared according to the preparation requirements for standard decoction of Chinese herbal medicine containing volatile oil. With cinnamaldehyde as the quantitative index, the transfer rate and extraction rate were calculated; pH value was determined and HPLC fingerprint analysis method was established. By the measurement of 14 batches of standard decoction, the transfer rate ranged from 25.0% to 68.4%; the extraction rate was at a range of 3.7% to 10.1% and pH was 3.72 to 5.48. Then the Similarity Evaluation System for Chromatographic Fingerprint of Traditional Chinese Medicine (2012A) was used to analyze and compare the fingerprints. Four common peaks were determined and three were identified including coumarin (peak 1), cinnamic acid (peak 2) and cinnamaldehyde (peak 3). Moreover, the similarity was 1.0. This study established an HPLC fingerprint analysis method of processed Cinnamomi Cortex standard decoction. The method showed good precision, stability and repeatability in fingerprint analysis, with significance in identification. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/29676083/[Research_on_quality_standard_of_processed_Cinnamomi_Cortex_decoction_pieces_containing_volatile_oil]_ DB - PRIME DP - Unbound Medicine ER -