Tags

Type your tag names separated by a space and hit enter

Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease.
Nutrients. 2018 Apr 20; 10(4)N

Abstract

Chronic kidney disease and reduced glomerular filtration rate are risk factors for the development of chronic metabolic acidosis. The prevention or correction of chronic metabolic acidosis has been found to slow progression of chronic kidney disease. Dietary composition can strongly affect acid⁻base balance. Major determinants of net endogenous acid production are the generation of large amounts of hydrogen ions, mostly by animal-derived protein, which is counterbalanced by the metabolism of base-producing foods like fruits and vegetables. Alkali therapy of chronic metabolic acidosis can be achieved by providing an alkali-rich diet or oral administration of alkali salts. The primary goal of dietary treatment should be to increase the proportion of fruits and vegetables and to reduce the daily protein intake to 0.8⁻1.0 g per kg body weight. Diet modifications should begin early, i.e., even in patients with moderate kidney impairment, because usual dietary habits of many developed societies contribute an increased proportion of acid equivalents due to the high intake of protein from animal sources.

Authors+Show Affiliations

University Stone Centre, Department of Urology, University of Bonn, Sigmund-Freud-Straβe 25, D-53105 Bonn, Germany. Roswitha.Siener@ukbonn.de.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29677110

Citation

Siener, Roswitha. "Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease." Nutrients, vol. 10, no. 4, 2018.
Siener R. Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease. Nutrients. 2018;10(4).
Siener, R. (2018). Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease. Nutrients, 10(4). https://doi.org/10.3390/nu10040512
Siener R. Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease. Nutrients. 2018 Apr 20;10(4) PubMed PMID: 29677110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary Treatment of Metabolic Acidosis in Chronic Kidney Disease. A1 - Siener,Roswitha, Y1 - 2018/04/20/ PY - 2018/03/27/received PY - 2018/04/14/revised PY - 2018/04/17/accepted PY - 2018/4/21/entrez PY - 2018/4/21/pubmed PY - 2018/9/25/medline KW - alkali citrate KW - bicarbonate KW - fruits KW - kidney disease KW - metabolic acidosis KW - protein KW - urinary stones KW - urolithiasis KW - vegetables JF - Nutrients JO - Nutrients VL - 10 IS - 4 N2 - Chronic kidney disease and reduced glomerular filtration rate are risk factors for the development of chronic metabolic acidosis. The prevention or correction of chronic metabolic acidosis has been found to slow progression of chronic kidney disease. Dietary composition can strongly affect acid⁻base balance. Major determinants of net endogenous acid production are the generation of large amounts of hydrogen ions, mostly by animal-derived protein, which is counterbalanced by the metabolism of base-producing foods like fruits and vegetables. Alkali therapy of chronic metabolic acidosis can be achieved by providing an alkali-rich diet or oral administration of alkali salts. The primary goal of dietary treatment should be to increase the proportion of fruits and vegetables and to reduce the daily protein intake to 0.8⁻1.0 g per kg body weight. Diet modifications should begin early, i.e., even in patients with moderate kidney impairment, because usual dietary habits of many developed societies contribute an increased proportion of acid equivalents due to the high intake of protein from animal sources. SN - 2072-6643 UR - https://www.unboundmedicine.com/medline/citation/29677110/Dietary_Treatment_of_Metabolic_Acidosis_in_Chronic_Kidney_Disease_ L2 - https://www.mdpi.com/resolver?pii=nu10040512 DB - PRIME DP - Unbound Medicine ER -