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Selection of Avibacterium paragallinarum Page serovar B strains for an infectious coryza vaccine.
Vet Immunol Immunopathol 2018; 199:77-80VI

Abstract

Infectious coryza is an important respiratory disease of chickens around the world and is caused by Avibacterium paragallinarum. Among the three Page serovars currently recognized for this bacterium, serovar B is a major circulating serovar in China nowadays. The cross-protection ability of the Page serovar B reference strain (0222) and five local isolates was evaluated by a vaccination-challenge trial in SPF chickens. The clinical signs seen in control birds challenged by strain 0222 and isolate HB 01 were significantly different, with isolate HB 01 giving more severe clinical signs. In terms of cross-protection, the protection in the groups vaccinated with isolate HB 01 and BJ 02 was significantly higher than that in the groups vaccinated with 0222 and the other three isolates. In addition, an experimental oil adjuvant trivalent vaccine, containing field isolate HB 01 antigen, was compared for immune efficacy with two commercial trivalent infectious coryza vaccines containing internationally recognized serovar B strains. The experimental oil adjuvant trivalent vaccine elicited best protection (80%) among the three trivalent vaccines. In conclusion, the oil adjuvant vaccine, containing field isolate HB 01 may be a better choice in control of current serovar B Av. paragallinarum outbreaks in China under current circumstances.

Authors+Show Affiliations

Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Science, Beijing, 100097, China. Electronic address: sunhuiling01@163.com.Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Science, Beijing, 100097, China.Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Science, Beijing, 100097, China.Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Science, Beijing, 100097, China.Beijing E-feed & E-vet Cooperation, Beijing, 100029, China.Faculty of Natural and Agricultural Science, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, Bloemfontein, 9300, South Africa.Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Science, Beijing, 100097, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29678233

Citation

Sun, Huiling, et al. "Selection of Avibacterium Paragallinarum Page Serovar B Strains for an Infectious Coryza Vaccine." Veterinary Immunology and Immunopathology, vol. 199, 2018, pp. 77-80.
Sun H, Xie S, Li X, et al. Selection of Avibacterium paragallinarum Page serovar B strains for an infectious coryza vaccine. Vet Immunol Immunopathol. 2018;199:77-80.
Sun, H., Xie, S., Li, X., Xu, F., Li, Y., Boucher, C. E., & Chen, X. (2018). Selection of Avibacterium paragallinarum Page serovar B strains for an infectious coryza vaccine. Veterinary Immunology and Immunopathology, 199, pp. 77-80. doi:10.1016/j.vetimm.2018.04.001.
Sun H, et al. Selection of Avibacterium Paragallinarum Page Serovar B Strains for an Infectious Coryza Vaccine. Vet Immunol Immunopathol. 2018;199:77-80. PubMed PMID: 29678233.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Selection of Avibacterium paragallinarum Page serovar B strains for an infectious coryza vaccine. AU - Sun,Huiling, AU - Xie,Sanlei, AU - Li,Xiaofei, AU - Xu,Fuzhou, AU - Li,Yi, AU - Boucher,Charlotte E, AU - Chen,Xiaoling, Y1 - 2018/04/05/ PY - 2017/04/21/received PY - 2018/03/03/revised PY - 2018/04/04/accepted PY - 2018/4/22/entrez PY - 2018/4/22/pubmed PY - 2018/9/19/medline KW - Avibacterium paragallinarum KW - Cross-protection KW - Infectious coryza KW - Page serovar B SP - 77 EP - 80 JF - Veterinary immunology and immunopathology JO - Vet. Immunol. Immunopathol. VL - 199 N2 - Infectious coryza is an important respiratory disease of chickens around the world and is caused by Avibacterium paragallinarum. Among the three Page serovars currently recognized for this bacterium, serovar B is a major circulating serovar in China nowadays. The cross-protection ability of the Page serovar B reference strain (0222) and five local isolates was evaluated by a vaccination-challenge trial in SPF chickens. The clinical signs seen in control birds challenged by strain 0222 and isolate HB 01 were significantly different, with isolate HB 01 giving more severe clinical signs. In terms of cross-protection, the protection in the groups vaccinated with isolate HB 01 and BJ 02 was significantly higher than that in the groups vaccinated with 0222 and the other three isolates. In addition, an experimental oil adjuvant trivalent vaccine, containing field isolate HB 01 antigen, was compared for immune efficacy with two commercial trivalent infectious coryza vaccines containing internationally recognized serovar B strains. The experimental oil adjuvant trivalent vaccine elicited best protection (80%) among the three trivalent vaccines. In conclusion, the oil adjuvant vaccine, containing field isolate HB 01 may be a better choice in control of current serovar B Av. paragallinarum outbreaks in China under current circumstances. SN - 1873-2534 UR - https://www.unboundmedicine.com/medline/citation/29678233/Selection_of_Avibacterium_paragallinarum_Page_serovar_B_strains_for_an_infectious_coryza_vaccine_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-2427(17)30198-8 DB - PRIME DP - Unbound Medicine ER -