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How do electronic cigarettes affect cravings to smoke or vape? Parsing the influences of nicotine and expectancies using the balanced-placebo design.
J Consult Clin Psychol. 2018 05; 86(5):486-491.JC

Abstract

OBJECTIVE

Although electronic cigarettes (e-cigarettes) are frequently initiated for smoking cessation, results from the first two clinical trials testing this suggest that the perceived benefits of vaping may be influenced by non-nicotine factors, including cognitive outcome expectancies. The current study investigated the separate and combined effects of nicotine delivery and outcome expectancies on cravings for cigarettes and e-cigarettes using a balanced-placebo experiment.

METHOD

Drug dosage (contains nicotine or not) was crossed with instructional set (told nicotine or non-nicotine) during ad lib e-cigarette use sessions by 128 current e-cigarette users (52 identifying as current cigarette smokers or "dual users"). It was hypothesized that reduction in craving for both cigarettes and e-cigarettes following e-cigarette administration would be driven primarily by the instructional set manipulation, reflecting the influence of outcome expectancies.

RESULTS

As hypothesized, among dual users, a main effect of instructional set emerged on reductions in craving to smoke cigarettes, with participants who were told that their e-cigarette contained nicotine reporting greater craving reduction (p = .046). With respect to reduced cravings for e-cigarettes, we found an interaction between drug dose and instructional set (p = .02) such that nicotine e-cigarettes reduced cravings more than non-nicotine e-cigarettes only among participants told to expect nicotine.

CONCLUSIONS

Findings suggest that cognitive expectancies contribute to the acute effects of e-cigarettes on craving, which may provide guidance for their potential as smoking cessation aids. (PsycINFO Database Record

Authors+Show Affiliations

Department of Psychology, University of South Florida.Department of Psychology, University of South Florida.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

29683704

Citation

Palmer, Amanda M., and Thomas H. Brandon. "How Do Electronic Cigarettes Affect Cravings to Smoke or Vape? Parsing the Influences of Nicotine and Expectancies Using the Balanced-placebo Design." Journal of Consulting and Clinical Psychology, vol. 86, no. 5, 2018, pp. 486-491.
Palmer AM, Brandon TH. How do electronic cigarettes affect cravings to smoke or vape? Parsing the influences of nicotine and expectancies using the balanced-placebo design. J Consult Clin Psychol. 2018;86(5):486-491.
Palmer, A. M., & Brandon, T. H. (2018). How do electronic cigarettes affect cravings to smoke or vape? Parsing the influences of nicotine and expectancies using the balanced-placebo design. Journal of Consulting and Clinical Psychology, 86(5), 486-491. https://doi.org/10.1037/ccp0000303
Palmer AM, Brandon TH. How Do Electronic Cigarettes Affect Cravings to Smoke or Vape? Parsing the Influences of Nicotine and Expectancies Using the Balanced-placebo Design. J Consult Clin Psychol. 2018;86(5):486-491. PubMed PMID: 29683704.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - How do electronic cigarettes affect cravings to smoke or vape? Parsing the influences of nicotine and expectancies using the balanced-placebo design. AU - Palmer,Amanda M, AU - Brandon,Thomas H, PY - 2018/4/24/entrez PY - 2018/4/24/pubmed PY - 2019/7/4/medline SP - 486 EP - 491 JF - Journal of consulting and clinical psychology JO - J Consult Clin Psychol VL - 86 IS - 5 N2 - OBJECTIVE: Although electronic cigarettes (e-cigarettes) are frequently initiated for smoking cessation, results from the first two clinical trials testing this suggest that the perceived benefits of vaping may be influenced by non-nicotine factors, including cognitive outcome expectancies. The current study investigated the separate and combined effects of nicotine delivery and outcome expectancies on cravings for cigarettes and e-cigarettes using a balanced-placebo experiment. METHOD: Drug dosage (contains nicotine or not) was crossed with instructional set (told nicotine or non-nicotine) during ad lib e-cigarette use sessions by 128 current e-cigarette users (52 identifying as current cigarette smokers or "dual users"). It was hypothesized that reduction in craving for both cigarettes and e-cigarettes following e-cigarette administration would be driven primarily by the instructional set manipulation, reflecting the influence of outcome expectancies. RESULTS: As hypothesized, among dual users, a main effect of instructional set emerged on reductions in craving to smoke cigarettes, with participants who were told that their e-cigarette contained nicotine reporting greater craving reduction (p = .046). With respect to reduced cravings for e-cigarettes, we found an interaction between drug dose and instructional set (p = .02) such that nicotine e-cigarettes reduced cravings more than non-nicotine e-cigarettes only among participants told to expect nicotine. CONCLUSIONS: Findings suggest that cognitive expectancies contribute to the acute effects of e-cigarettes on craving, which may provide guidance for their potential as smoking cessation aids. (PsycINFO Database Record SN - 1939-2117 UR - https://www.unboundmedicine.com/medline/citation/29683704/How_do_electronic_cigarettes_affect_cravings_to_smoke_or_vape_Parsing_the_influences_of_nicotine_and_expectancies_using_the_balanced_placebo_design_ DB - PRIME DP - Unbound Medicine ER -