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Pituitary fossa chondrosarcoma: An unusual cause of a sellar suprasellar mass masquerading as pituitary adenoma.
Surg Neurol Int. 2018; 9:76.SN

Abstract

BACKGROUND

Chondrosarcoma is a mesenchymal malignant tumor composed of tumor cells producing cartilage. It is more commonly found in older age group and usually affects the axial skeleton. Intracranial chondrosarcoma is extremely rare, and chondrosarcoma arising from the sellar region are even rarer with only a few cases described in the literature. We report a case of chondrosarcoma mimicking a sellar suprasellar mass with parasellar extension.

CASE DESCRIPTION

A 22-year old male presented with generalized intermittent headache along with diplopia and diminished visual acuity without any history of sexual dysfunction or galactorrhea. His endocrine tests were within normal limits. Magnetic resonance imaging of the brain revealed a large mass which was apparently arising from the sella with a significant suprasellar and left parasellar component with mild compression over the left optic chiasm and deviation of infundibulum to the right. The patient underwent pterional craniotomy and decompression of the mass. The pathologic diagnosis was chondrosarcoma. The patient received postoperative radiotherapy.

CONCLUSION

This case demonstrates that chondrosarcoma of the sellar region may mimic clinical, endocrinological, and radiological features of more commonly encountered lesions in this region such as nonfunctioning pituitary tumor, craniopharyngioma, meningioma, or chordoma. We discuss the origin, areas of involvement, management, and long-term prognosis of these rare tumors.

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Authors+Show Affiliations

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

29721355

Citation

Dutta, Gautam, et al. "Pituitary Fossa Chondrosarcoma: an Unusual Cause of a Sellar Suprasellar Mass Masquerading as Pituitary Adenoma." Surgical Neurology International, vol. 9, 2018, p. 76.

Dutta G, Singh D, Singh H, et al. Pituitary fossa chondrosarcoma: An unusual cause of a sellar suprasellar mass masquerading as pituitary adenoma. Surg Neurol Int. 2018;9:76.

Dutta, G., Singh, D., Singh, H., Srivastava, A. K., Jagetia, A., & Sachdeva, D. (2018). Pituitary fossa chondrosarcoma: An unusual cause of a sellar suprasellar mass masquerading as pituitary adenoma. Surgical Neurology International, 9, 76. https://doi.org/10.4103/sni.sni_455_17

Dutta G, et al. Pituitary Fossa Chondrosarcoma: an Unusual Cause of a Sellar Suprasellar Mass Masquerading as Pituitary Adenoma. Surg Neurol Int. 2018;9:76. PubMed PMID: 29721355.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - Pituitary fossa chondrosarcoma: An unusual cause of a sellar suprasellar mass masquerading as pituitary adenoma. AU - Dutta,Gautam, AU - Singh,Daljit, AU - Singh,Hukum, AU - Srivastava,Arvind Kumar, AU - Jagetia,Anita, AU - Sachdeva,Deepashu, Y1 - 2018/04/09/ PY - 2017/12/02/received PY - 2018/02/12/accepted PY - 2018/5/4/entrez PY - 2018/5/4/pubmed PY - 2018/5/4/medline KW - Chondrosarcoma KW - parasellar KW - sellar KW - suprasellar SP - 76 EP - 76 JF - Surgical neurology international JO - Surg Neurol Int VL - 9 N2 - BACKGROUND: Chondrosarcoma is a mesenchymal malignant tumor composed of tumor cells producing cartilage. It is more commonly found in older age group and usually affects the axial skeleton. Intracranial chondrosarcoma is extremely rare, and chondrosarcoma arising from the sellar region are even rarer with only a few cases described in the literature. We report a case of chondrosarcoma mimicking a sellar suprasellar mass with parasellar extension. CASE DESCRIPTION: A 22-year old male presented with generalized intermittent headache along with diplopia and diminished visual acuity without any history of sexual dysfunction or galactorrhea. His endocrine tests were within normal limits. Magnetic resonance imaging of the brain revealed a large mass which was apparently arising from the sella with a significant suprasellar and left parasellar component with mild compression over the left optic chiasm and deviation of infundibulum to the right. The patient underwent pterional craniotomy and decompression of the mass. The pathologic diagnosis was chondrosarcoma. The patient received postoperative radiotherapy. CONCLUSION: This case demonstrates that chondrosarcoma of the sellar region may mimic clinical, endocrinological, and radiological features of more commonly encountered lesions in this region such as nonfunctioning pituitary tumor, craniopharyngioma, meningioma, or chordoma. We discuss the origin, areas of involvement, management, and long-term prognosis of these rare tumors. SN - 2229-5097 UR - https://www.unboundmedicine.com/medline/citation/29721355/Pituitary_fossa_chondrosarcoma:_An_unusual_cause_of_a_sellar_suprasellar_mass_masquerading_as_pituitary_adenoma_ DB - PRIME DP - Unbound Medicine ER -