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Inadvertent epidural administration of potassium chloride. A case report.
Can J Anaesth. 1988 Nov; 35(6):631-3.CJ

Abstract

A 24-year-old black female presented for repeat elective Caesarean section. The procedure was performed under epidural anaesthesia. Sufentanil 25 micrograms, intended for postoperative analgesia, was inadvertently diluted to 10 ml with 15 per cent potassium chloride (KCl) instead of preservative-free normal saline (0.9 per cent NaCl). This solution was then injected via an epidural catheter into the epidural space at the conclusion of surgery. Two hours after injection of the sufetanil-KCl mixture, the patient had a level of sensory blockade to T1 and diaphoresis above this level. Painful muscle spasms had also developed below T1. One hour later she developed hypertension which required hydralazine 10 mg and labetalol 25 mg IV for treatment. The patient was treated supportively with oxygen. Dexamethasone 10 mg was administered intravenously to reduce spinal cord oedema. Intravenous diazepam 10 mg and meperidine 75 mg were given for sedation and analgesia. Complete recovery occurred within 12 hours.

Authors+Show Affiliations

Tessler MJ
Department of Anaesthesia, St. Boniface General Hospital, University of Manitoba, Winnipeg.
White I
No affiliation info available
Naugler-Colville M
No affiliation info available
Biehl DR
No affiliation info available

MeSH

AdultAnesthesia, EpiduralAnesthesia, ObstetricalCesarean SectionFemaleFentanylHumansHypertensionMedication ErrorsMuscle SpasticityPain, PostoperativePotassium ChlorideSufentanil

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2974323

Citation

Tessler, M J., et al. "Inadvertent Epidural Administration of Potassium Chloride. a Case Report." Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie, vol. 35, no. 6, 1988, pp. 631-3.
Tessler MJ, White I, Naugler-Colville M, et al. Inadvertent epidural administration of potassium chloride. A case report. Can J Anaesth. 1988;35(6):631-3.
Tessler, M. J., White, I., Naugler-Colville, M., & Biehl, D. R. (1988). Inadvertent epidural administration of potassium chloride. A case report. Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie, 35(6), 631-3.
Tessler MJ, et al. Inadvertent Epidural Administration of Potassium Chloride. a Case Report. Can J Anaesth. 1988;35(6):631-3. PubMed PMID: 2974323.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Inadvertent epidural administration of potassium chloride. A case report. AU - Tessler,M J, AU - White,I, AU - Naugler-Colville,M, AU - Biehl,D R, PY - 1988/11/1/pubmed PY - 1988/11/1/medline PY - 1988/11/1/entrez SP - 631 EP - 3 JF - Canadian journal of anaesthesia = Journal canadien d'anesthesie JO - Can J Anaesth VL - 35 IS - 6 N2 - A 24-year-old black female presented for repeat elective Caesarean section. The procedure was performed under epidural anaesthesia. Sufentanil 25 micrograms, intended for postoperative analgesia, was inadvertently diluted to 10 ml with 15 per cent potassium chloride (KCl) instead of preservative-free normal saline (0.9 per cent NaCl). This solution was then injected via an epidural catheter into the epidural space at the conclusion of surgery. Two hours after injection of the sufetanil-KCl mixture, the patient had a level of sensory blockade to T1 and diaphoresis above this level. Painful muscle spasms had also developed below T1. One hour later she developed hypertension which required hydralazine 10 mg and labetalol 25 mg IV for treatment. The patient was treated supportively with oxygen. Dexamethasone 10 mg was administered intravenously to reduce spinal cord oedema. Intravenous diazepam 10 mg and meperidine 75 mg were given for sedation and analgesia. Complete recovery occurred within 12 hours. SN - 0832-610X UR - https://www.unboundmedicine.com/medline/citation/2974323/Inadvertent_epidural_administration_of_potassium_chloride__A_case_report_ DB - PRIME DP - Unbound Medicine ER -