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Posttraumatic stress disorder, depression, and suicidal ideation in veterans: Results from the mind your heart study.
Psychiatry Res. 2018 07; 265:224-230.PR

Abstract

Veterans with PTSD or depression are at increased risk for suicidal ideation. However, few studies have examined that risk in those with comorbid PTSD and depression, instead focusing on these disorders individually. This study investigates the association of suicidal ideation with comorbid PTSD and depression and examines the role of military and psychosocial covariates. We evaluated 746 veterans using the CAPS to assess PTSD and the PHQ-9 to measure depression and suicidal ideation. Covariates were assessed via validated self-report measures. 49% of veterans with comorbid PTSD and depression endorsed suicidal ideation, making them more likely to do so than those with depression alone (34%), PTSD alone (11%), or neither (2%). In multivariate logistic regression models, this association remained significant after controlling for demographics and symptom severity. Anger, hostility, anxiety, alcohol use, optimism and social support did not explain the elevated risk of suicidal ideation in the comorbid group in fully adjusted models. As suicidal ideation is a known risk factor for suicide attempts and completions, veterans with comorbid PTSD and depression represent a vulnerable group who may need more intensive monitoring and treatment to reduce risk of suicide.

Authors+Show Affiliations

San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA. Electronic address: marenson@umd.edu.San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA.San Francisco VA Medical Center, San Francisco, CA, USA; University of California, San Francisco, San Francisco, CA, USA. Electronic address: Beth.Cohen@va.gov.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

29753254

Citation

Arenson, Melanie B., et al. "Posttraumatic Stress Disorder, Depression, and Suicidal Ideation in Veterans: Results From the Mind Your Heart Study." Psychiatry Research, vol. 265, 2018, pp. 224-230.
Arenson MB, Whooley MA, Neylan TC, et al. Posttraumatic stress disorder, depression, and suicidal ideation in veterans: Results from the mind your heart study. Psychiatry Res. 2018;265:224-230.
Arenson, M. B., Whooley, M. A., Neylan, T. C., Maguen, S., Metzler, T. J., & Cohen, B. E. (2018). Posttraumatic stress disorder, depression, and suicidal ideation in veterans: Results from the mind your heart study. Psychiatry Research, 265, 224-230. https://doi.org/10.1016/j.psychres.2018.04.046
Arenson MB, et al. Posttraumatic Stress Disorder, Depression, and Suicidal Ideation in Veterans: Results From the Mind Your Heart Study. Psychiatry Res. 2018;265:224-230. PubMed PMID: 29753254.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Posttraumatic stress disorder, depression, and suicidal ideation in veterans: Results from the mind your heart study. AU - Arenson,Melanie B, AU - Whooley,Mary A, AU - Neylan,Thomas C, AU - Maguen,Shira, AU - Metzler,Thomas J, AU - Cohen,Beth E, Y1 - 2018/04/22/ PY - 2017/07/26/received PY - 2018/04/12/revised PY - 2018/04/12/accepted PY - 2018/5/13/pubmed PY - 2019/1/10/medline PY - 2018/5/13/entrez KW - Depression KW - Military KW - Posttraumatic stress disorder KW - Suicidal ideation KW - Veterans’ health SP - 224 EP - 230 JF - Psychiatry research JO - Psychiatry Res VL - 265 N2 - Veterans with PTSD or depression are at increased risk for suicidal ideation. However, few studies have examined that risk in those with comorbid PTSD and depression, instead focusing on these disorders individually. This study investigates the association of suicidal ideation with comorbid PTSD and depression and examines the role of military and psychosocial covariates. We evaluated 746 veterans using the CAPS to assess PTSD and the PHQ-9 to measure depression and suicidal ideation. Covariates were assessed via validated self-report measures. 49% of veterans with comorbid PTSD and depression endorsed suicidal ideation, making them more likely to do so than those with depression alone (34%), PTSD alone (11%), or neither (2%). In multivariate logistic regression models, this association remained significant after controlling for demographics and symptom severity. Anger, hostility, anxiety, alcohol use, optimism and social support did not explain the elevated risk of suicidal ideation in the comorbid group in fully adjusted models. As suicidal ideation is a known risk factor for suicide attempts and completions, veterans with comorbid PTSD and depression represent a vulnerable group who may need more intensive monitoring and treatment to reduce risk of suicide. SN - 1872-7123 UR - https://www.unboundmedicine.com/medline/citation/29753254/Posttraumatic_stress_disorder_depression_and_suicidal_ideation_in_veterans:_Results_from_the_mind_your_heart_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(17)31356-2 DB - PRIME DP - Unbound Medicine ER -