Citation
Khajuria, Chitvan, et al. "Development and Characterization of the First dsRNA-resistant Insect Population From Western Corn Rootworm, Diabrotica Virgifera Virgifera LeConte." PloS One, vol. 13, no. 5, 2018, pp. e0197059.
Khajuria C, Ivashuta S, Wiggins E, et al. Development and characterization of the first dsRNA-resistant insect population from western corn rootworm, Diabrotica virgifera virgifera LeConte. PLoS One. 2018;13(5):e0197059.
Khajuria, C., Ivashuta, S., Wiggins, E., Flagel, L., Moar, W., Pleau, M., Miller, K., Zhang, Y., Ramaseshadri, P., Jiang, C., Hodge, T., Jensen, P., Chen, M., Gowda, A., McNulty, B., Vazquez, C., Bolognesi, R., Haas, J., Head, G., & Clark, T. (2018). Development and characterization of the first dsRNA-resistant insect population from western corn rootworm, Diabrotica virgifera virgifera LeConte. PloS One, 13(5), e0197059. https://doi.org/10.1371/journal.pone.0197059
Khajuria C, et al. Development and Characterization of the First dsRNA-resistant Insect Population From Western Corn Rootworm, Diabrotica Virgifera Virgifera LeConte. PLoS One. 2018;13(5):e0197059. PubMed PMID: 29758046.
TY - JOUR
T1 - Development and characterization of the first dsRNA-resistant insect population from western corn rootworm, Diabrotica virgifera virgifera LeConte.
AU - Khajuria,Chitvan,
AU - Ivashuta,Sergey,
AU - Wiggins,Elizabeth,
AU - Flagel,Lex,
AU - Moar,William,
AU - Pleau,Michael,
AU - Miller,Kaylee,
AU - Zhang,Yuanji,
AU - Ramaseshadri,Parthasarathy,
AU - Jiang,Changjian,
AU - Hodge,Tracey,
AU - Jensen,Peter,
AU - Chen,Mao,
AU - Gowda,Anilkumar,
AU - McNulty,Brian,
AU - Vazquez,Cara,
AU - Bolognesi,Renata,
AU - Haas,Jeffrey,
AU - Head,Graham,
AU - Clark,Thomas,
Y1 - 2018/05/14/
PY - 2018/01/02/received
PY - 2018/04/25/accepted
PY - 2018/5/15/entrez
PY - 2018/5/15/pubmed
PY - 2018/8/1/medline
SP - e0197059
EP - e0197059
JF - PloS one
JO - PLoS One
VL - 13
IS - 5
N2 - The use of dsRNA to control insect pests via the RNA interference (RNAi) pathway is being explored by researchers globally. However, with every new class of insect control compounds, the evolution of insect resistance needs to be considered, and understanding resistance mechanisms is essential in designing durable technologies and effective resistance management strategies. To gain insight into insect resistance to dsRNA, a field screen with subsequent laboratory selection was used to establish a population of DvSnf7 dsRNA-resistant western corn rootworm, Diabrotica virgifera virgifera, a major maize insect pest. WCR resistant to ingested DvSnf7 dsRNA had impaired luminal uptake and resistance was not DvSnf7 dsRNA-specific, as indicated by cross resistance to all other dsRNAs tested. No resistance to the Bacillus thuringiensis Cry3Bb1 protein was observed. DvSnf7 dsRNA resistance was inherited recessively, located on a single locus, and autosomal. Together these findings will provide insights for dsRNA deployment for insect pest control.
SN - 1932-6203
UR - https://www.unboundmedicine.com/medline/citation/29758046/Development_and_characterization_of_the_first_dsRNA_resistant_insect_population_from_western_corn_rootworm_Diabrotica_virgifera_virgifera_LeConte_
DB - PRIME
DP - Unbound Medicine
ER -
