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Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria.
Parasite Epidemiol Control. 2017 May; 2(2):21-29.PE

Abstract

There is a hypothesis that Mass drug administration (MDA) of ivermectin and albendazole for the treatment of onchocerciasis and lymphatic filariasis could have an impact on the burden of soil-transmitted helminthiasis (STH) in MDA communities. We, therefore, assessed the burden of STH (Ascaris lumbricoides, Trichuris trichiura, and hookworm) infections in nine communities from 3 LGAs (two MDA local government areas (LGAs) and one control LGA) in Kebbi State, Nigeria after 5-years (2010-2015) of MDA for onchocerciasis and/or lymphatic filariasis. We also administered questionnaire to obtain demographic information and history of MDA in the past five years. The three LGAs are Bagudo (Ivermectin MDA); Zuru (Ivermectin/Albendazole MDA) and Dandi (No MDA). The study was a cross sectional survey. The total number of people that complied with provision of stool samples and questionnaire were 1357 persons; stool samples collected were examined for STH infections in the three LGAs. Zuru LGA had the highest prevalence of STH (41.89, 95% CI: 37.08-46.81) followed by Dandi LGA (24.66, 95% CI: 20.69-28.97) and Bagudo LGA (3.36, 95% CI: 1.97-5.32). Prevalence of STH infection was not significantly different among age group and sex. Geometric mean intensity per gram of infection for both A. lumbricoides and Hookworm were highest in Zuru LGA with (1.16 GMI, 95% CI: 0.97-1.36) and (1.49 GMI, 95% CI: 1.29-1.70) respectively. Treatment coverage was less than 65% from 2010 to 2013 in the intervention LGAs. The study shows that STH is still a public health problem in Zuru LGA (IVM + ALB) and requires MDA of albendazole for STH control to continue, while Dandi LGA (No MDA history) requires MDA with albendazole to scale up treatment for STH control.

Authors+Show Affiliations

Federal University of Agriculture, Abeokuta 110001, Ogun State, Nigeria.Sightsavers Nigeria Country Office, 1 Golf Course Road, P.O Box 503, Kaduna, Nigeria.State Ministry of Health, Birnin Kebbi, Nigeria.Sightsavers Nigeria Country Office, 1 Golf Course Road, P.O Box 503, Kaduna, Nigeria.Sightsavers Nigeria Country Office, 1 Golf Course Road, P.O Box 503, Kaduna, Nigeria.Sightsavers Regional office, Accra, Ghana.Federal University of Agriculture, Abeokuta 110001, Ogun State, Nigeria.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

29774278

Citation

Oluwole, Akinola Stephen, et al. "Assessment of the Burden of Soil-transmitted Helminthiasis After Five Years of Mass Drug Administration for Onchocerciasis and Lymphatic Filariasis in Kebbi State, Nigeria." Parasite Epidemiology and Control, vol. 2, no. 2, 2017, pp. 21-29.
Oluwole AS, Isiyaku S, Aliero AA, et al. Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria. Parasite Epidemiol Control. 2017;2(2):21-29.
Oluwole, A. S., Isiyaku, S., Aliero, A. A., Nwosu, C., William, A., Elhassan, E., & Ekpo, U. F. (2017). Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria. Parasite Epidemiology and Control, 2(2), 21-29. https://doi.org/10.1016/j.parepi.2017.01.002
Oluwole AS, et al. Assessment of the Burden of Soil-transmitted Helminthiasis After Five Years of Mass Drug Administration for Onchocerciasis and Lymphatic Filariasis in Kebbi State, Nigeria. Parasite Epidemiol Control. 2017;2(2):21-29. PubMed PMID: 29774278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessment of the burden of soil-transmitted helminthiasis after five years of mass drug administration for Onchocerciasis and Lymphatic filariasis in Kebbi State, Nigeria. AU - Oluwole,Akinola Stephen, AU - Isiyaku,Sunday, AU - Aliero,Attahiru Aliyu, AU - Nwosu,Christian, AU - William,Adamani, AU - Elhassan,Elizabeth, AU - Ekpo,Uwem Friday, Y1 - 2017/02/09/ PY - 2016/09/21/received PY - 2017/01/10/revised PY - 2017/01/10/accepted PY - 2018/5/19/entrez PY - 2017/2/9/pubmed PY - 2017/2/9/medline KW - Assessment KW - Control KW - Lymphatic filariasis KW - Mass drug administration KW - Onchocerciasis KW - Soil-transmitted helminthiasis SP - 21 EP - 29 JF - Parasite epidemiology and control JO - Parasite Epidemiol Control VL - 2 IS - 2 N2 - There is a hypothesis that Mass drug administration (MDA) of ivermectin and albendazole for the treatment of onchocerciasis and lymphatic filariasis could have an impact on the burden of soil-transmitted helminthiasis (STH) in MDA communities. We, therefore, assessed the burden of STH (Ascaris lumbricoides, Trichuris trichiura, and hookworm) infections in nine communities from 3 LGAs (two MDA local government areas (LGAs) and one control LGA) in Kebbi State, Nigeria after 5-years (2010-2015) of MDA for onchocerciasis and/or lymphatic filariasis. We also administered questionnaire to obtain demographic information and history of MDA in the past five years. The three LGAs are Bagudo (Ivermectin MDA); Zuru (Ivermectin/Albendazole MDA) and Dandi (No MDA). The study was a cross sectional survey. The total number of people that complied with provision of stool samples and questionnaire were 1357 persons; stool samples collected were examined for STH infections in the three LGAs. Zuru LGA had the highest prevalence of STH (41.89, 95% CI: 37.08-46.81) followed by Dandi LGA (24.66, 95% CI: 20.69-28.97) and Bagudo LGA (3.36, 95% CI: 1.97-5.32). Prevalence of STH infection was not significantly different among age group and sex. Geometric mean intensity per gram of infection for both A. lumbricoides and Hookworm were highest in Zuru LGA with (1.16 GMI, 95% CI: 0.97-1.36) and (1.49 GMI, 95% CI: 1.29-1.70) respectively. Treatment coverage was less than 65% from 2010 to 2013 in the intervention LGAs. The study shows that STH is still a public health problem in Zuru LGA (IVM + ALB) and requires MDA of albendazole for STH control to continue, while Dandi LGA (No MDA history) requires MDA with albendazole to scale up treatment for STH control. SN - 2405-6731 UR - https://www.unboundmedicine.com/medline/citation/29774278/Assessment_of_the_burden_of_soil_transmitted_helminthiasis_after_five_years_of_mass_drug_administration_for_Onchocerciasis_and_Lymphatic_filariasis_in_Kebbi_State_Nigeria_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S2405-6731(16)30040-X DB - PRIME DP - Unbound Medicine ER -
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