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Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria.
BMC Psychiatry. 2018 05 18; 18(1):133.BP

Abstract

BACKGROUND

Functional dyspepsia (FD) is considered a bio-psychosocial disorder. The role of psychosocial factors in FD pathogenesis remains unclear.

METHODS

This study evaluated sleep quality and mood symptoms in patients with FD, assessing the associations of FD severity, disordered sleep, and psychological symptoms. One-hundred-and-fifteen adult patients with typical FD symptoms were enrolled alongside 61 healthy volunteers. Rome III criteria were used to evaluate FD symptoms; sleep disorder was assessed with the Pittsburgh Sleep Quality Index (PSQI), and Symptom Checklist-90-Revised (SCL-90R) was utilized to determine the status of depression, anxiety and other psychological symptoms.

RESULTS

PSQI scores and nine symptomatic dimensions of SCL-90R were significantly higher in FD patients than in controls. Multiple logistic regression indicated that lower BMI, lower level of education, and sleep disturbance were independently associated with FD and FD subgroups. Hostility and phobic anxiety were independent risk factors for FD. Further analysis showed that hostility was an independent risk factor for both FD subgroups, and somatization and additional psychiatric symptoms for epigastric pain syndrome.

CONCLUSIONS

We found that FD was associated with sleep disorder and psychopathological factors. These findings suggest that implementing sleeping and/or psychological therapies may help reduce FD symptoms.

Authors+Show Affiliations

Department of Psychiatry, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Psychiatry, Zhongda Hospital, Southeast University, Nanjing, 210029, China.Department of Psychiatry, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Psychiatry, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Psychiatry, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Psychiatry, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.Department of Traditional Chinese Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. weimuxin@njmu.edu.cn.Department of Gastroenterology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. lin9100@aliyun.com.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

29776354

Citation

Li, Yong, et al. "Sleep Disturbance and Psychological Distress Are Associated With Functional Dyspepsia Based On Rome III Criteria." BMC Psychiatry, vol. 18, no. 1, 2018, p. 133.
Li Y, Gong Y, Li Y, et al. Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria. BMC Psychiatry. 2018;18(1):133.
Li, Y., Gong, Y., Li, Y., He, D., Wu, Y., Wang, H., Cong, X., Wei, M., & Lin, L. (2018). Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria. BMC Psychiatry, 18(1), 133. https://doi.org/10.1186/s12888-018-1720-0
Li Y, et al. Sleep Disturbance and Psychological Distress Are Associated With Functional Dyspepsia Based On Rome III Criteria. BMC Psychiatry. 2018 05 18;18(1):133. PubMed PMID: 29776354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sleep disturbance and psychological distress are associated with functional dyspepsia based on Rome III criteria. AU - Li,Yong, AU - Gong,Yaoyao, AU - Li,Yinghui, AU - He,Danjun, AU - Wu,Yuqin, AU - Wang,Haofei, AU - Cong,Xiaoyin, AU - Wei,Muxin, AU - Lin,Lin, Y1 - 2018/05/18/ PY - 2018/02/07/received PY - 2018/05/03/accepted PY - 2018/5/20/entrez PY - 2018/5/20/pubmed PY - 2019/3/6/medline KW - Functional dyspepsia KW - Psychological factors KW - Rome III criteria KW - Sleep disturbance SP - 133 EP - 133 JF - BMC psychiatry JO - BMC Psychiatry VL - 18 IS - 1 N2 - BACKGROUND: Functional dyspepsia (FD) is considered a bio-psychosocial disorder. The role of psychosocial factors in FD pathogenesis remains unclear. METHODS: This study evaluated sleep quality and mood symptoms in patients with FD, assessing the associations of FD severity, disordered sleep, and psychological symptoms. One-hundred-and-fifteen adult patients with typical FD symptoms were enrolled alongside 61 healthy volunteers. Rome III criteria were used to evaluate FD symptoms; sleep disorder was assessed with the Pittsburgh Sleep Quality Index (PSQI), and Symptom Checklist-90-Revised (SCL-90R) was utilized to determine the status of depression, anxiety and other psychological symptoms. RESULTS: PSQI scores and nine symptomatic dimensions of SCL-90R were significantly higher in FD patients than in controls. Multiple logistic regression indicated that lower BMI, lower level of education, and sleep disturbance were independently associated with FD and FD subgroups. Hostility and phobic anxiety were independent risk factors for FD. Further analysis showed that hostility was an independent risk factor for both FD subgroups, and somatization and additional psychiatric symptoms for epigastric pain syndrome. CONCLUSIONS: We found that FD was associated with sleep disorder and psychopathological factors. These findings suggest that implementing sleeping and/or psychological therapies may help reduce FD symptoms. SN - 1471-244X UR - https://www.unboundmedicine.com/medline/citation/29776354/Sleep_disturbance_and_psychological_distress_are_associated_with_functional_dyspepsia_based_on_Rome_III_criteria_ L2 - https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-018-1720-0 DB - PRIME DP - Unbound Medicine ER -