Tags

Type your tag names separated by a space and hit enter

Differential toxin profiles of ciguatoxins in marine organisms: Chemistry, fate and global distribution.
Toxicon. 2018 Aug; 150:124-143.T

Abstract

Ciguatoxins (CTXs) are fish metabolism products and a result of biotransformation of precursor gambiertoxins produced, in the first instance, by benthic dinoflagellates Gambierdiscus and Fukuyoa. Ciguatoxins are potent neurotoxins that selectively open voltage gated sodium channels in excitable cells causing the human food poisoning known as Ciguatera (CFP). Endemic from tropical areas in central Pacific and West Indian Ocean, and the Caribbean Sea, CTX may affect up to 500,000 people annually due to fish consumption. Their recent occurrence in European waters highlights the need for a multidisciplinary approach of CTX research in order to better understand the diversity and transformation of microalgae products through food webs. This article intends to review available information on chemistry, toxicity, distribution and fate of known CTX compounds from a critical perspective to provide an overview of future trends and needs on ciguatera research.

Authors+Show Affiliations

IPMA - Instituto Português do Mar e da Atmosfera, Rua Alfredo Magalhães Ramalho, 6, 1495-006, Lisbon, Portugal; CCMAR - Centre of Marine Sciences, University of Algarve, Campus of Gambelas, 8005-139, Faro, Portugal. Electronic address: lucia.solino@ipma.pt.IPMA - Instituto Português do Mar e da Atmosfera, Rua Alfredo Magalhães Ramalho, 6, 1495-006, Lisbon, Portugal; CCMAR - Centre of Marine Sciences, University of Algarve, Campus of Gambelas, 8005-139, Faro, Portugal. Electronic address: prcosta@ipma.pt.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29778594

Citation

Soliño, Lucía, and Pedro Reis Costa. "Differential Toxin Profiles of Ciguatoxins in Marine Organisms: Chemistry, Fate and Global Distribution." Toxicon : Official Journal of the International Society On Toxinology, vol. 150, 2018, pp. 124-143.
Soliño L, Costa PR. Differential toxin profiles of ciguatoxins in marine organisms: Chemistry, fate and global distribution. Toxicon. 2018;150:124-143.
Soliño, L., & Costa, P. R. (2018). Differential toxin profiles of ciguatoxins in marine organisms: Chemistry, fate and global distribution. Toxicon : Official Journal of the International Society On Toxinology, 150, 124-143. https://doi.org/10.1016/j.toxicon.2018.05.005
Soliño L, Costa PR. Differential Toxin Profiles of Ciguatoxins in Marine Organisms: Chemistry, Fate and Global Distribution. Toxicon. 2018;150:124-143. PubMed PMID: 29778594.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differential toxin profiles of ciguatoxins in marine organisms: Chemistry, fate and global distribution. AU - Soliño,Lucía, AU - Costa,Pedro Reis, Y1 - 2018/05/17/ PY - 2018/02/28/received PY - 2018/05/11/revised PY - 2018/05/13/accepted PY - 2018/5/21/pubmed PY - 2018/11/27/medline PY - 2018/5/21/entrez KW - Ciguatera KW - Ciguatoxin KW - Gambierdiscus KW - Marine toxins SP - 124 EP - 143 JF - Toxicon : official journal of the International Society on Toxinology JO - Toxicon VL - 150 N2 - Ciguatoxins (CTXs) are fish metabolism products and a result of biotransformation of precursor gambiertoxins produced, in the first instance, by benthic dinoflagellates Gambierdiscus and Fukuyoa. Ciguatoxins are potent neurotoxins that selectively open voltage gated sodium channels in excitable cells causing the human food poisoning known as Ciguatera (CFP). Endemic from tropical areas in central Pacific and West Indian Ocean, and the Caribbean Sea, CTX may affect up to 500,000 people annually due to fish consumption. Their recent occurrence in European waters highlights the need for a multidisciplinary approach of CTX research in order to better understand the diversity and transformation of microalgae products through food webs. This article intends to review available information on chemistry, toxicity, distribution and fate of known CTX compounds from a critical perspective to provide an overview of future trends and needs on ciguatera research. SN - 1879-3150 UR - https://www.unboundmedicine.com/medline/citation/29778594/Differential_toxin_profiles_of_ciguatoxins_in_marine_organisms:_Chemistry_fate_and_global_distribution_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-0101(18)30193-4 DB - PRIME DP - Unbound Medicine ER -
Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.