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Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders.
Curr Pharm Des. 2018; 24(18):1916-1925.CP

Abstract

BACKGROUND

Physical activity can be involved in the prevention of gastrointestinal (GI)-tract diseases, however, the results regarding the volume and the intensity of exercise considered as beneficial for protection of gastrointestinal organs are conflicting.

AIMS AND METHODS

The main objective of this review is to provide a comprehensive and updated overview on the beneficial and harmful effects of physical activity on the gastrointestinal tract. We attempted to discuss recent evidence regarding the association between different modes and intensity levels of exercise and physiological functions of the gut and gut pathology.

RESULTS

The regular, moderate exercise can exert a beneficial effect on GI-tract disorders such as reflux esophagitis, peptic ulcers, cholelithiasis, constipation and Inflammatory Bowel Disease (IBD) leading to the attenuation of the symptoms. This voluntary exercise has been shown to reduce the risk of colorectal cancer. On the other hand, there is considerable evidence that the high-intensity training or prolonged endurance training can exert a negative influence on GI-tract resulting in the exacerbation of symptoms.

CONCLUSION

Physical activity can exhibit a beneficial effect on a variety of gastrointestinal diseases, however, this effect depends upon the exercise mode, duration and intensity. The accumulated evidence indicate that management of gastrointestinal problems and their relief by the exercise seems to be complicated and require adjustments of physical activity training, dietary measures and medical monitoring of symptoms. More experimental and clinical studies on the effects of physical activity on GI-tract disorders are warranted. Especially, the association between the exercise intensity and data addressing the underlying mechanism(s) of the exercise as the complementary therapy in the treatment of gastrointestinal disorders, require further determination in animal models and humans.

Authors+Show Affiliations

Department of Ergonomics and Exercise Physiology, Faculty of Health Sciences, Jagiellonian University Medical College, Cracow, Poland.Department of Ergonomics and Exercise Physiology, Faculty of Health Sciences, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.Department of Physiology, Faculty of Medicine, Jagiellonian University Medical College, Cracow, Poland.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

29788876

Citation

Bilski, Jan, et al. "Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders." Current Pharmaceutical Design, vol. 24, no. 18, 2018, pp. 1916-1925.
Bilski J, Mazur-Bialy A, Magierowski M, et al. Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders. Curr Pharm Des. 2018;24(18):1916-1925.
Bilski, J., Mazur-Bialy, A., Magierowski, M., Kwiecien, S., Wojcik, D., Ptak-Belowska, A., Surmiak, M., Targosz, A., Magierowska, K., & Brzozowski, T. (2018). Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders. Current Pharmaceutical Design, 24(18), 1916-1925. https://doi.org/10.2174/1381612824666180522103759
Bilski J, et al. Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders. Curr Pharm Des. 2018;24(18):1916-1925. PubMed PMID: 29788876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Exploiting Significance of Physical Exercise in Prevention of Gastrointestinal Disorders. AU - Bilski,Jan, AU - Mazur-Bialy,Agnieszka, AU - Magierowski,Marcin, AU - Kwiecien,Slawomir, AU - Wojcik,Dagmara, AU - Ptak-Belowska,Agata, AU - Surmiak,Marcin, AU - Targosz,Aneta, AU - Magierowska,Katarzyna, AU - Brzozowski,Tomasz, PY - 2018/04/10/received PY - 2018/05/04/revised PY - 2018/05/15/accepted PY - 2018/5/24/pubmed PY - 2019/10/18/medline PY - 2018/5/24/entrez KW - Gastrointestinal tract KW - benefits KW - forced endurance training KW - hazards KW - myokines KW - physical activity KW - voluntary exercise. SP - 1916 EP - 1925 JF - Current pharmaceutical design JO - Curr Pharm Des VL - 24 IS - 18 N2 - BACKGROUND: Physical activity can be involved in the prevention of gastrointestinal (GI)-tract diseases, however, the results regarding the volume and the intensity of exercise considered as beneficial for protection of gastrointestinal organs are conflicting. AIMS AND METHODS: The main objective of this review is to provide a comprehensive and updated overview on the beneficial and harmful effects of physical activity on the gastrointestinal tract. We attempted to discuss recent evidence regarding the association between different modes and intensity levels of exercise and physiological functions of the gut and gut pathology. RESULTS: The regular, moderate exercise can exert a beneficial effect on GI-tract disorders such as reflux esophagitis, peptic ulcers, cholelithiasis, constipation and Inflammatory Bowel Disease (IBD) leading to the attenuation of the symptoms. This voluntary exercise has been shown to reduce the risk of colorectal cancer. On the other hand, there is considerable evidence that the high-intensity training or prolonged endurance training can exert a negative influence on GI-tract resulting in the exacerbation of symptoms. CONCLUSION: Physical activity can exhibit a beneficial effect on a variety of gastrointestinal diseases, however, this effect depends upon the exercise mode, duration and intensity. The accumulated evidence indicate that management of gastrointestinal problems and their relief by the exercise seems to be complicated and require adjustments of physical activity training, dietary measures and medical monitoring of symptoms. More experimental and clinical studies on the effects of physical activity on GI-tract disorders are warranted. Especially, the association between the exercise intensity and data addressing the underlying mechanism(s) of the exercise as the complementary therapy in the treatment of gastrointestinal disorders, require further determination in animal models and humans. SN - 1873-4286 UR - https://www.unboundmedicine.com/medline/citation/29788876/Exploiting_Significance_of_Physical_Exercise_in_Prevention_of_Gastrointestinal_Disorders_ L2 - http://www.eurekaselect.com/162337/article DB - PRIME DP - Unbound Medicine ER -