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[Acupuncture combined with western medicine on rheumatoid arthritis and effects on blood stasis].

Abstract

OBJECTIVE

To observe the clinical efficacy of acupuncture combined with western medicine in the treatment of rheumatoid arthritis (RA) and its effect on blood stasis, and to explore ways to improve the clinical curative effect.

METHODS

A total of 56 patients of RA were randomly divided into an observation group and a control group, 28 cases in each one. ① ibuprofen sustained-release tablets, 2 times a day, each time 0.3 g; ② methotrexate tablets (MTX), once a week, each time 10 mg ③ folic acid tablets, once a week, each time 5 mg were given in the control group, 30 days as one course, a total of 3 courses were required. In the observation group, acupuncture was adopted on the basis of the treatment as the control group. The main acupoints were Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Hegu (LI 4), Quchi (LI 11), Zusanli (ST 36) combined with local ashi points. The treatment was given once every day for continuous 6 days a week, the treatment for 30 days as one course, a total of 3 courses were required. The serological indexs were evaluated before and after treatment, including the rheumatoid factor (RF), hypersensitive C-reactive protein (hs-CRP), erythrocyte sedirnentation rate (ESR), platelet (PLT), fibrinogen (FBG) and D-dimer (D-D), the changes of disease activity score (DAS-28), symptom grade quantitative score, blood stasis syndrome symptom (the joint tingling, lip color, tongue, pulse, subcutaneous ecchymosis, squamous and dry skin) score were observed.

RESULTS

① The scores of RF, hs-CRP, ESR, PLT, D-D, FBG, DAS-28 and symptom grade quantitative were significantly improved in the two groups compared with those before treatment (all P<0.05), and the scores of hs-CRP, ESR, DAS-28 and symptom grading in the observation group were more better than those in the control group (all P<0.05). ② The total score of joint tingling, lip color, tongue, pulse, subcutaneous ecchymosis, squamous and dry skin and blood stasis syndrome in both groups were decreased after treatment (all P<0.05), the joint tingling, tongue, lip color and subcutaneous ecchymosis were improved obviously in the observation group than those in the control group (all P<0.05). ③ The total effective rate in the observation group was 85.7% (24/28), which was better than 75.0% (21/28) in the control group (P<0.05).

CONCLUSION

Acupuncture combined with western medicine can not only improve the clinical efficacy of RA patients but also improve the blood stasis.

Authors+Show Affiliations

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The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

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The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

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The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

,

The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

,

The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

,

The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

The Geriatrics, the Second Hospital Affiliated of Anhui University of CM, Hefei 230061, China.

Source

MeSH

Acupuncture Points
Acupuncture Therapy
Arthritis, Rheumatoid
Combined Modality Therapy
Folic Acid
Humans
Ibuprofen
Methotrexate
Treatment Outcome

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

chi

PubMed ID

29797911

Citation

Zhu, Yan, et al. "[Acupuncture Combined With Western Medicine On Rheumatoid Arthritis and Effects On Blood Stasis]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 38, no. 5, 2018, pp. 4793-82.
Zhu Y, Yu H, Pan Y, et al. [Acupuncture combined with western medicine on rheumatoid arthritis and effects on blood stasis]. Zhongguo Zhen Jiu. 2018;38(5):4793-82.
Zhu, Y., Yu, H., Pan, Y., Yang, J., Wu, B., Hu, X., & Cao, Y. (2018). [Acupuncture combined with western medicine on rheumatoid arthritis and effects on blood stasis]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 38(5), pp. 4793-82. doi:10.13703/j.0255-2930.2018.05.008.
Zhu Y, et al. [Acupuncture Combined With Western Medicine On Rheumatoid Arthritis and Effects On Blood Stasis]. Zhongguo Zhen Jiu. 2018 May 12;38(5):4793-82. PubMed PMID: 29797911.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Acupuncture combined with western medicine on rheumatoid arthritis and effects on blood stasis]. AU - Zhu,Yan, AU - Yu,Hongwu, AU - Pan,Yuzhen, AU - Yang,Jia, AU - Wu,Bingkun, AU - Hu,Xue, AU - Cao,Yunyan, PY - 2018/5/26/entrez PY - 2018/5/26/pubmed PY - 2018/8/18/medline KW - acupuncture KW - blood stasis KW - disease activity score (DAS-28) KW - erythrocyte sedimentation rate (ESR) KW - hypersensitive C-reactive protein (hs-CRP) KW - rheumatoid arthritis KW - rheumatoid factor (RF) SP - 4793 EP - 82 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 38 IS - 5 N2 - OBJECTIVE: To observe the clinical efficacy of acupuncture combined with western medicine in the treatment of rheumatoid arthritis (RA) and its effect on blood stasis, and to explore ways to improve the clinical curative effect. METHODS: A total of 56 patients of RA were randomly divided into an observation group and a control group, 28 cases in each one. ① ibuprofen sustained-release tablets, 2 times a day, each time 0.3 g; ② methotrexate tablets (MTX), once a week, each time 10 mg ③ folic acid tablets, once a week, each time 5 mg were given in the control group, 30 days as one course, a total of 3 courses were required. In the observation group, acupuncture was adopted on the basis of the treatment as the control group. The main acupoints were Ganshu (BL 18), Pishu (BL 20), Shenshu (BL 23), Hegu (LI 4), Quchi (LI 11), Zusanli (ST 36) combined with local ashi points. The treatment was given once every day for continuous 6 days a week, the treatment for 30 days as one course, a total of 3 courses were required. The serological indexs were evaluated before and after treatment, including the rheumatoid factor (RF), hypersensitive C-reactive protein (hs-CRP), erythrocyte sedirnentation rate (ESR), platelet (PLT), fibrinogen (FBG) and D-dimer (D-D), the changes of disease activity score (DAS-28), symptom grade quantitative score, blood stasis syndrome symptom (the joint tingling, lip color, tongue, pulse, subcutaneous ecchymosis, squamous and dry skin) score were observed. RESULTS: ① The scores of RF, hs-CRP, ESR, PLT, D-D, FBG, DAS-28 and symptom grade quantitative were significantly improved in the two groups compared with those before treatment (all P<0.05), and the scores of hs-CRP, ESR, DAS-28 and symptom grading in the observation group were more better than those in the control group (all P<0.05). ② The total score of joint tingling, lip color, tongue, pulse, subcutaneous ecchymosis, squamous and dry skin and blood stasis syndrome in both groups were decreased after treatment (all P<0.05), the joint tingling, tongue, lip color and subcutaneous ecchymosis were improved obviously in the observation group than those in the control group (all P<0.05). ③ The total effective rate in the observation group was 85.7% (24/28), which was better than 75.0% (21/28) in the control group (P<0.05). CONCLUSION: Acupuncture combined with western medicine can not only improve the clinical efficacy of RA patients but also improve the blood stasis. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/29797911/[Acupuncture_combined_with_western_medicine_on_rheumatoid_arthritis_and_effects_on_blood_stasis]_ L2 - http://www.diseaseinfosearch.org/result/592 DB - PRIME DP - Unbound Medicine ER -