Tags

Type your tag names separated by a space and hit enter

[Clinical research and the effect mechanism on premature ovarian failure treated with acupuncture in recent 20 years].
Zhongguo Zhen Jiu 2018; 38(5):5653-70ZZ

Abstract

OBJECTIVE

To review and collect the study achievements and the effect mechanism of acupuncture in the treatment of premature ovarian failure (POF) in recent 20 years so as to provide more references for the clinical treatment of POF with acupuncture.

METHODS

Through retrieving PubMed, CNKI and VIP, the literature on acupuncture for POF was collected from January 1, 1998 through March 31, 2017 regarding the rule of acupoint selection and the therapeutic method. The potential effect mechanism was explored.

RESULTS

Finally, 26 papers on the clinical treatment for POF with acupuncture and 5 ones on the laboratory mechanism were obtained. The differentiated syndromes and the top 3 acupoints for the treatment of POF included shaoyin syndrome [Taixi (KI 3), Sanyinjiao (SP 6) and Guanyuan (CV 4)], Taiyin syndrome [Sanyinjiao (SP 6), Zusanli (ST 36) and Ciliao (BL 32)], jueyin syndrome [Taichong (LR 3), Shenting (GV 24), Guanyuan (CV 4)], the mixed syndrome of shaoyin and jueyin [Sanyinjiao (SP 6), Ganshu (BL 18) and Shenshu (BL 23)], the mixed syndrome of shaoyin and taiyin [Pishu (BL 20), Sanyinjiao (SP 6) and Zusanli (ST 36)] and the dysfunction of the thoroughfare vessel and the conception vessel [Guanyuan (CV 4), Zigong (EX-CA 1) and Huangshu (KI 16)]. The top 5 acupoints of the 14 meridians were Guanyuan (CV 4), Shenshu (BL 23), Sanyinjiao (SP 6), Zhongji (CV 3), Pishu (BL 20), Taixi (KI 3) and Ganshu (BL 18). The local extraordinary points were dominant. According to the use frequency of the acupoints, the first top 5 meridians were the bladder meridian of foot-taiyang, the governor vessel, the conception vessel, the spleen meridian of foot-taiyin and the kidney meridian of foot-shaoyin. The most acupoints were distributed in the chest, the abdomen, the lumber region and the lower limbs. Many therapeutic methods were used, such as acupuncture with filiform needle, electroacupuncture, moxibustion and the acupoint thread-embedding therapy. The effect mechanisms possibly referred to the recovery of the sexual level through regulating the hypothalamus-pituitary gland-ovarian axle (HPOA) function, the improvement of the histological morphology of the uterine, the improvement of body immunity through affecting the nerve-endocrine-immune regulation system as well as the regulation of the genetic and protein expressions of the signal pathway relevant with POF.

CONCLUSION

Even though acupuncture has achieved the therapeutic effects in the clinical treatment of POF, the research on the effect mechanism is still limited. The exploration of acupuncture for POF in terms of mechanism may guide the clinical practice. In the future study, the clinical pathway should be specified and the effect mechanism be explored through the rigorous laboratory design and more objective and rational evaluation system.

Authors+Show Affiliations

Nanjing Medical University, Nanjing 210029, Jiangsu Province, China.Nanjing Medical University, Nanjing 210029, Jiangsu Province, China; Nanjing University of CM, Nanjing 210023, Jiangsu Province.

Pub Type(s)

Journal Article
Review

Language

chi

PubMed ID

29797923

Citation

Xia, Liangjun, and Youbing Xia. "[Clinical Research and the Effect Mechanism On Premature Ovarian Failure Treated With Acupuncture in Recent 20 Years]." Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, vol. 38, no. 5, 2018, pp. 5653-70.
Xia L, Xia Y. [Clinical research and the effect mechanism on premature ovarian failure treated with acupuncture in recent 20 years]. Zhongguo Zhen Jiu. 2018;38(5):5653-70.
Xia, L., & Xia, Y. (2018). [Clinical research and the effect mechanism on premature ovarian failure treated with acupuncture in recent 20 years]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion, 38(5), pp. 5653-70. doi:10.13703/j.0255-2930.2018.05.031.
Xia L, Xia Y. [Clinical Research and the Effect Mechanism On Premature Ovarian Failure Treated With Acupuncture in Recent 20 Years]. Zhongguo Zhen Jiu. 2018 May 12;38(5):5653-70. PubMed PMID: 29797923.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical research and the effect mechanism on premature ovarian failure treated with acupuncture in recent 20 years]. AU - Xia,Liangjun, AU - Xia,Youbing, PY - 2018/5/26/entrez PY - 2018/5/26/pubmed PY - 2018/8/18/medline KW - acupoint frequency KW - acupuncture KW - clinic KW - electroacupuncture KW - filiform needle KW - mechanism KW - moxibustion KW - premature ovarian failure KW - review KW - thread-embedding therapy SP - 5653 EP - 70 JF - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JO - Zhongguo Zhen Jiu VL - 38 IS - 5 N2 - OBJECTIVE: To review and collect the study achievements and the effect mechanism of acupuncture in the treatment of premature ovarian failure (POF) in recent 20 years so as to provide more references for the clinical treatment of POF with acupuncture. METHODS: Through retrieving PubMed, CNKI and VIP, the literature on acupuncture for POF was collected from January 1, 1998 through March 31, 2017 regarding the rule of acupoint selection and the therapeutic method. The potential effect mechanism was explored. RESULTS: Finally, 26 papers on the clinical treatment for POF with acupuncture and 5 ones on the laboratory mechanism were obtained. The differentiated syndromes and the top 3 acupoints for the treatment of POF included shaoyin syndrome [Taixi (KI 3), Sanyinjiao (SP 6) and Guanyuan (CV 4)], Taiyin syndrome [Sanyinjiao (SP 6), Zusanli (ST 36) and Ciliao (BL 32)], jueyin syndrome [Taichong (LR 3), Shenting (GV 24), Guanyuan (CV 4)], the mixed syndrome of shaoyin and jueyin [Sanyinjiao (SP 6), Ganshu (BL 18) and Shenshu (BL 23)], the mixed syndrome of shaoyin and taiyin [Pishu (BL 20), Sanyinjiao (SP 6) and Zusanli (ST 36)] and the dysfunction of the thoroughfare vessel and the conception vessel [Guanyuan (CV 4), Zigong (EX-CA 1) and Huangshu (KI 16)]. The top 5 acupoints of the 14 meridians were Guanyuan (CV 4), Shenshu (BL 23), Sanyinjiao (SP 6), Zhongji (CV 3), Pishu (BL 20), Taixi (KI 3) and Ganshu (BL 18). The local extraordinary points were dominant. According to the use frequency of the acupoints, the first top 5 meridians were the bladder meridian of foot-taiyang, the governor vessel, the conception vessel, the spleen meridian of foot-taiyin and the kidney meridian of foot-shaoyin. The most acupoints were distributed in the chest, the abdomen, the lumber region and the lower limbs. Many therapeutic methods were used, such as acupuncture with filiform needle, electroacupuncture, moxibustion and the acupoint thread-embedding therapy. The effect mechanisms possibly referred to the recovery of the sexual level through regulating the hypothalamus-pituitary gland-ovarian axle (HPOA) function, the improvement of the histological morphology of the uterine, the improvement of body immunity through affecting the nerve-endocrine-immune regulation system as well as the regulation of the genetic and protein expressions of the signal pathway relevant with POF. CONCLUSION: Even though acupuncture has achieved the therapeutic effects in the clinical treatment of POF, the research on the effect mechanism is still limited. The exploration of acupuncture for POF in terms of mechanism may guide the clinical practice. In the future study, the clinical pathway should be specified and the effect mechanism be explored through the rigorous laboratory design and more objective and rational evaluation system. SN - 0255-2930 UR - https://www.unboundmedicine.com/medline/citation/29797923/[Clinical_research_and_the_effect_mechanism_on_premature_ovarian_failure_treated_with_acupuncture_in_recent_20_years]_ L2 - http://www.diseaseinfosearch.org/result/5929 DB - PRIME DP - Unbound Medicine ER -