Tags

Type your tag names separated by a space and hit enter

A prospective observational trial of fusion imaging in infrarenal aneurysms.
J Vasc Surg. 2018 12; 68(6):1706-1713.e1.JV

Abstract

OBJECTIVE

Use of three-dimensional fusion has been shown to significantly reduce radiation exposure and contrast material use in complex (fenestrated and branched) endovascular aneurysm repair (EVAR). Cydar software (CYDAR Medical, Cambridge, United Kingdom) is a cloud-based technology that can provide imaging guidance by overlaying preoperative three-dimensional vessel anatomy from computed tomography scans onto live fluoroscopy images both in hybrid operating rooms and on mobile C-arms. The aim of this study was to determine whether radiation dose reduction would occur with the addition of fusion imaging to infrarenal repair in all imaging environments.

METHODS

All patients who consented to involvement in the trial and who were treated with EVAR in our center from March 2016 until April 2017 were included. A teaching session about radiation protection and Cydar fusion software use was provided to all operators before the start of the fusion group enrollment. This group was compared with a retrospective cohort of patients treated in the same center from March 2015 to March 2016, after a dedicated program of radiation awareness and reduction was introduced. Ruptured aneurysms and complex EVAR were excluded. Preoperative and perioperative characteristics were recorded, including parameters of radiation dose, such as air kerma and dose-area product. Results were expressed in median and interquartile range.

RESULTS

Forty-four patients were prospectively enrolled and compared with 21 retrospective control patients. No significant differences were found in comparing sex, body mass index, and age at repair. The median operation time (wire to wire) and fluoroscopy time were 90 (75-105) minutes and 30 (22-34) minutes, respectively, without significant differences between groups (P = .56 and P = .36). Dose-area product was nonsignificantly higher in the control group, 21.7 (8.9-85.9) Gy cm2, compared with the fusion group, 12.4 (7.5-23.4) Gy cm2 (P = .10). Air kerma product was significantly higher in the control group, 142 (61-541) mGy, compared with 82 (51-115) mGy in the fusion group (P = .03). The number of digital subtraction angiography runs was significantly lower in the fusion group (8 [6-11]) compared with the control group (10 [9-14]); (P = .03). There were no significant differences in the frequency of adverse events, endoleaks, or additional procedures required.

CONCLUSIONS

When it is used in simple procedures such as infrarenal aneurysm repair, image-based fusion technology is feasible both in hybrid operating rooms and on mobile systems and leads to an overall 50% reduction in radiation dose. Fusion technology should become standard of care for centers attempting to maximize radiation dose reduction, even if capital investment of a hybrid operating room is not feasible.

Authors+Show Affiliations

Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom; Department of Vascular Surgery, Institut du Thorax, CHU Nantes, Nantes, France.Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom.Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom.Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom.Department of Vascular Surgery, Institut du Thorax, CHU Nantes, Nantes, France.Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom.Aortic Team, Vascular Surgery Directorate, The Royal Free London, London, United Kingdom. Electronic address: tara.mastracci@nhs.net.

Pub Type(s)

Journal Article
Observational Study

Language

eng

PubMed ID

29804734

Citation

Maurel, Blandine, et al. "A Prospective Observational Trial of Fusion Imaging in Infrarenal Aneurysms." Journal of Vascular Surgery, vol. 68, no. 6, 2018, pp. 1706-1713.e1.
Maurel B, Martin-Gonzalez T, Chong D, et al. A prospective observational trial of fusion imaging in infrarenal aneurysms. J Vasc Surg. 2018;68(6):1706-1713.e1.
Maurel, B., Martin-Gonzalez, T., Chong, D., Irwin, A., Guimbretière, G., Davis, M., & Mastracci, T. M. (2018). A prospective observational trial of fusion imaging in infrarenal aneurysms. Journal of Vascular Surgery, 68(6), 1706-e1. https://doi.org/10.1016/j.jvs.2018.04.015
Maurel B, et al. A Prospective Observational Trial of Fusion Imaging in Infrarenal Aneurysms. J Vasc Surg. 2018;68(6):1706-1713.e1. PubMed PMID: 29804734.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A prospective observational trial of fusion imaging in infrarenal aneurysms. AU - Maurel,Blandine, AU - Martin-Gonzalez,Teresa, AU - Chong,Debra, AU - Irwin,Andrew, AU - Guimbretière,Guillaume, AU - Davis,Meryl, AU - Mastracci,Tara M, Y1 - 2018/05/24/ PY - 2017/09/17/received PY - 2018/04/04/accepted PY - 2018/5/29/pubmed PY - 2019/3/15/medline PY - 2018/5/29/entrez KW - Advanced imaging guidance software KW - Automated overlay KW - EVAR KW - Imaging fusion KW - Radiation exposure SP - 1706 EP - 1713.e1 JF - Journal of vascular surgery JO - J. Vasc. Surg. VL - 68 IS - 6 N2 - OBJECTIVE: Use of three-dimensional fusion has been shown to significantly reduce radiation exposure and contrast material use in complex (fenestrated and branched) endovascular aneurysm repair (EVAR). Cydar software (CYDAR Medical, Cambridge, United Kingdom) is a cloud-based technology that can provide imaging guidance by overlaying preoperative three-dimensional vessel anatomy from computed tomography scans onto live fluoroscopy images both in hybrid operating rooms and on mobile C-arms. The aim of this study was to determine whether radiation dose reduction would occur with the addition of fusion imaging to infrarenal repair in all imaging environments. METHODS: All patients who consented to involvement in the trial and who were treated with EVAR in our center from March 2016 until April 2017 were included. A teaching session about radiation protection and Cydar fusion software use was provided to all operators before the start of the fusion group enrollment. This group was compared with a retrospective cohort of patients treated in the same center from March 2015 to March 2016, after a dedicated program of radiation awareness and reduction was introduced. Ruptured aneurysms and complex EVAR were excluded. Preoperative and perioperative characteristics were recorded, including parameters of radiation dose, such as air kerma and dose-area product. Results were expressed in median and interquartile range. RESULTS: Forty-four patients were prospectively enrolled and compared with 21 retrospective control patients. No significant differences were found in comparing sex, body mass index, and age at repair. The median operation time (wire to wire) and fluoroscopy time were 90 (75-105) minutes and 30 (22-34) minutes, respectively, without significant differences between groups (P = .56 and P = .36). Dose-area product was nonsignificantly higher in the control group, 21.7 (8.9-85.9) Gy cm2, compared with the fusion group, 12.4 (7.5-23.4) Gy cm2 (P = .10). Air kerma product was significantly higher in the control group, 142 (61-541) mGy, compared with 82 (51-115) mGy in the fusion group (P = .03). The number of digital subtraction angiography runs was significantly lower in the fusion group (8 [6-11]) compared with the control group (10 [9-14]); (P = .03). There were no significant differences in the frequency of adverse events, endoleaks, or additional procedures required. CONCLUSIONS: When it is used in simple procedures such as infrarenal aneurysm repair, image-based fusion technology is feasible both in hybrid operating rooms and on mobile systems and leads to an overall 50% reduction in radiation dose. Fusion technology should become standard of care for centers attempting to maximize radiation dose reduction, even if capital investment of a hybrid operating room is not feasible. SN - 1097-6809 UR - https://www.unboundmedicine.com/medline/citation/29804734/A_prospective_observational_trial_of_fusion_imaging_in_infrarenal_aneurysms_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0741-5214(18)30892-9 DB - PRIME DP - Unbound Medicine ER -