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Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis.
BMJ Case Rep. 2018 Jun 08; 2018BC

Abstract

We report a 1-year follow-up of a young woman with anti-N-methyl-D-aspartate receptor encephalitis. Management of autoimmune encephalitis remains challenging as objective and clinically relevant biomarkers are sought, which allow for the monitoring of treatment response. While further investigation is required, we believe that this case highlights the importance of following a comprehensive neuropsychological profile as a clinically relevant biomarker to guide therapeutic decision-making. By relying on the neuropsychological assessment of the patient, treatment with more toxic medications was avoided and her antiepileptic drug regimen was simplified.

Authors+Show Affiliations

Psychiatry and Behavioral Sciences, Northwestern Memorial Hospital, Chicago, Illinois, USA.Psychiatry and Behavioral Sciences, Northwestern Memorial Hospital, Chicago, Illinois, USA. Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Department of Neurology, Northwestern Memorial Hospital, Chicago, Illinois, USA.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29884664

Citation

Sieg, Erica, et al. "Neuropsychological Assessment as an Objective Tool to Monitor Treatment Response in anti-N-methyl-D-aspartate Receptor Encephalitis." BMJ Case Reports, vol. 2018, 2018.
Sieg E, Brook M, Linnoila J, et al. Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis. BMJ Case Rep. 2018;2018.
Sieg, E., Brook, M., Linnoila, J., & VanHaerents, S. (2018). Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis. BMJ Case Reports, 2018. https://doi.org/10.1136/bcr-2018-224169
Sieg E, et al. Neuropsychological Assessment as an Objective Tool to Monitor Treatment Response in anti-N-methyl-D-aspartate Receptor Encephalitis. BMJ Case Rep. 2018 Jun 8;2018 PubMed PMID: 29884664.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis. AU - Sieg,Erica, AU - Brook,Michael, AU - Linnoila,Jenny, AU - VanHaerents,Stephen, Y1 - 2018/06/08/ PY - 2018/6/10/entrez PY - 2018/6/10/pubmed PY - 2018/11/6/medline KW - clinical neurophysiology KW - epilepsy and seizures KW - immunology KW - memory disorders (psychiatry) JF - BMJ case reports JO - BMJ Case Rep VL - 2018 N2 - We report a 1-year follow-up of a young woman with anti-N-methyl-D-aspartate receptor encephalitis. Management of autoimmune encephalitis remains challenging as objective and clinically relevant biomarkers are sought, which allow for the monitoring of treatment response. While further investigation is required, we believe that this case highlights the importance of following a comprehensive neuropsychological profile as a clinically relevant biomarker to guide therapeutic decision-making. By relying on the neuropsychological assessment of the patient, treatment with more toxic medications was avoided and her antiepileptic drug regimen was simplified. SN - 1757-790X UR - https://www.unboundmedicine.com/medline/citation/29884664/Neuropsychological_assessment_as_an_objective_tool_to_monitor_treatment_response_in_anti_N_methyl_D_aspartate_receptor_encephalitis_ L2 - https://casereports.bmj.com/cgi/pmidlookup?view=long&pmid=29884664 DB - PRIME DP - Unbound Medicine ER -