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Do specialized bariatric multivitamins lower deficiencies after RYGB?

Abstract

BACKGROUND

One of the side effects of bariatric surgery is the risk of vitamin and mineral deficiencies. Vitamin B12, vitamin D, folate, and iron deficiencies are especially common among Roux-en-Y gastric bypass patients.

OBJECTIVE

To examine the effectiveness of a specialized multivitamin supplement for Roux-en-Y gastric bypass patients on deficiencies the first 3 years postoperatively, retrospectively in a large, prospectively collected cohort.

SETTING

Large specialized bariatric hospital.

RESULTS

One thousand one hundred sixty patients were included, 883 users and 258 who were nonusers of the specialized multivitamin. Patient characteristics and total weight were comparable. Higher serum concentrations of ferritin (124.7 ± 96.2 µg/L versus 106.0 ± 83.0 µg/L, P = .016), vitamin B12 (347.3 ± 145.1 pmol/L versus 276.8 ± 131.4 pmol/L, P<.001), folic acid (34.9 ± 9.6 nmol/L versus 25.4 ± 10.7 nmol/L, P<.001), and vitamin D (98.4 ± 28.7 nmol/L versus 90.0 ± 34.5 nmol/L, P = .002) were observed in users compared with nonusers after 1 year. Less new deficiencies were found for ferritin (1% versus 4%, P = .029), vitamin B12 (9% versus 23%, P<.001), and vitamin D (0% versus 4%, P<.001) in users compared with nonusers. Two and 3 years after the surgery these findings remained almost identical.

CONCLUSIONS

The use of specialized multivitamin supplements resulted in less deficiencies of vitamin B12, vitamin D, folic acid, and ferritin. The study showed that Roux-en-Y gastric bypass patients benefited from the specialized multivitamin supplements and it should be advised to this patient group.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands. Electronic address: wschijns@rijnstate.nl.

    ,

    Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands.

    ,

    Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands.

    ,

    Department of Surgery, Radboud UMC, Nijmegen, the Netherlands.

    ,

    Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands.

    Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands.

    Source

    MeSH

    Adult
    Avitaminosis
    Body Mass Index
    Cohort Studies
    Dietary Supplements
    Female
    Folic Acid Deficiency
    Follow-Up Studies
    Gastric Bypass
    Humans
    Male
    Middle Aged
    Netherlands
    Obesity, Morbid
    Retrospective Studies
    Risk Assessment
    Tertiary Care Centers
    Treatment Outcome
    Vitamin B 12 Deficiency
    Vitamin D Deficiency
    Vitamins

    Pub Type(s)

    Comparative Study
    Journal Article

    Language

    eng

    PubMed ID

    29903686

    Citation

    Schijns, Wendy, et al. "Do Specialized Bariatric Multivitamins Lower Deficiencies After RYGB?" Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, vol. 14, no. 7, 2018, pp. 1005-1012.
    Schijns W, Schuurman LT, Melse-Boonstra A, et al. Do specialized bariatric multivitamins lower deficiencies after RYGB? Surg Obes Relat Dis. 2018;14(7):1005-1012.
    Schijns, W., Schuurman, L. T., Melse-Boonstra, A., van Laarhoven, C. J. H. M., Berends, F. J., & Aarts, E. O. (2018). Do specialized bariatric multivitamins lower deficiencies after RYGB? Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, 14(7), pp. 1005-1012. doi:10.1016/j.soard.2018.03.029.
    Schijns W, et al. Do Specialized Bariatric Multivitamins Lower Deficiencies After RYGB. Surg Obes Relat Dis. 2018;14(7):1005-1012. PubMed PMID: 29903686.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Do specialized bariatric multivitamins lower deficiencies after RYGB? AU - Schijns,Wendy, AU - Schuurman,Lisanne T, AU - Melse-Boonstra,Alida, AU - van Laarhoven,Cees J H M, AU - Berends,Frits J, AU - Aarts,Edo O, Y1 - 2018/04/03/ PY - 2017/11/06/received PY - 2018/03/01/revised PY - 2018/03/28/accepted PY - 2018/6/16/pubmed PY - 2019/1/3/medline PY - 2018/6/16/entrez KW - Bariatric surgery KW - Deficiency KW - Mineral KW - Multivitamin KW - Obesity KW - Roux-en-Y gastric bypass KW - Specialized KW - Vitamin SP - 1005 EP - 1012 JF - Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery JO - Surg Obes Relat Dis VL - 14 IS - 7 N2 - BACKGROUND: One of the side effects of bariatric surgery is the risk of vitamin and mineral deficiencies. Vitamin B12, vitamin D, folate, and iron deficiencies are especially common among Roux-en-Y gastric bypass patients. OBJECTIVE: To examine the effectiveness of a specialized multivitamin supplement for Roux-en-Y gastric bypass patients on deficiencies the first 3 years postoperatively, retrospectively in a large, prospectively collected cohort. SETTING: Large specialized bariatric hospital. RESULTS: One thousand one hundred sixty patients were included, 883 users and 258 who were nonusers of the specialized multivitamin. Patient characteristics and total weight were comparable. Higher serum concentrations of ferritin (124.7 ± 96.2 µg/L versus 106.0 ± 83.0 µg/L, P = .016), vitamin B12 (347.3 ± 145.1 pmol/L versus 276.8 ± 131.4 pmol/L, P<.001), folic acid (34.9 ± 9.6 nmol/L versus 25.4 ± 10.7 nmol/L, P<.001), and vitamin D (98.4 ± 28.7 nmol/L versus 90.0 ± 34.5 nmol/L, P = .002) were observed in users compared with nonusers after 1 year. Less new deficiencies were found for ferritin (1% versus 4%, P = .029), vitamin B12 (9% versus 23%, P<.001), and vitamin D (0% versus 4%, P<.001) in users compared with nonusers. Two and 3 years after the surgery these findings remained almost identical. CONCLUSIONS: The use of specialized multivitamin supplements resulted in less deficiencies of vitamin B12, vitamin D, folic acid, and ferritin. The study showed that Roux-en-Y gastric bypass patients benefited from the specialized multivitamin supplements and it should be advised to this patient group. SN - 1878-7533 UR - https://www.unboundmedicine.com/medline/citation/29903686/Do_specialized_bariatric_multivitamins_lower_deficiencies_after_RYGB L2 - https://linkinghub.elsevier.com/retrieve/pii/S1550-7289(18)30168-0 DB - PRIME DP - Unbound Medicine ER -