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Transdermal rotigotine patch in Parkinson's disease with a history of intestinal operation.
BMJ Case Rep. 2018 Jun 15; 2018BC

Abstract

A 42-year-old Japanese man with a history of small intestine resection and familial Mediterranean fever was referred to our hospital for a second opinion on parkinsonism. At the age of 35, the patient attended a hospital due to impaired left-hand movement and resting tremor. He was previously diagnosed with multiple system atrophy based on the lack of effectiveness of levodopa treatment. With suspicion of malabsorption due to his history of ileostomy, a levodopa challenge test with levodopa intravenous infusion was conducted, and revealed a 65% improvement in Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale part III. Therefore, diagnosis of Parkinson's disease was made and a transdermal rotigotine patch was selected as a treatment. This treatment dose-dependently improved the patient's symptoms. The transdermal drug delivery should be considered when patients show dose failure due to malabsorption.

Authors+Show Affiliations

Department of Neurology, Juntendo University Faculty of Medicine, Tokyo, Japan.Department of Neurology, Juntendo University Faculty of Medicine, Tokyo, Japan.Department of Neurology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29909386

Citation

Ogawa, Takashi, et al. "Transdermal Rotigotine Patch in Parkinson's Disease With a History of Intestinal Operation." BMJ Case Reports, vol. 2018, 2018.
Ogawa T, Oyama G, Hattori N. Transdermal rotigotine patch in Parkinson's disease with a history of intestinal operation. BMJ Case Rep. 2018;2018.
Ogawa, T., Oyama, G., & Hattori, N. (2018). Transdermal rotigotine patch in Parkinson's disease with a history of intestinal operation. BMJ Case Reports, 2018. https://doi.org/10.1136/bcr-2017-223722
Ogawa T, Oyama G, Hattori N. Transdermal Rotigotine Patch in Parkinson's Disease With a History of Intestinal Operation. BMJ Case Rep. 2018 Jun 15;2018 PubMed PMID: 29909386.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Transdermal rotigotine patch in Parkinson's disease with a history of intestinal operation. AU - Ogawa,Takashi, AU - Oyama,Genko, AU - Hattori,Nobutaka, Y1 - 2018/06/15/ PY - 2018/6/18/entrez PY - 2018/6/18/pubmed PY - 2018/11/8/medline KW - neurology (drugs and medicines) KW - parkinson’s disease JF - BMJ case reports JO - BMJ Case Rep VL - 2018 N2 - A 42-year-old Japanese man with a history of small intestine resection and familial Mediterranean fever was referred to our hospital for a second opinion on parkinsonism. At the age of 35, the patient attended a hospital due to impaired left-hand movement and resting tremor. He was previously diagnosed with multiple system atrophy based on the lack of effectiveness of levodopa treatment. With suspicion of malabsorption due to his history of ileostomy, a levodopa challenge test with levodopa intravenous infusion was conducted, and revealed a 65% improvement in Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale part III. Therefore, diagnosis of Parkinson's disease was made and a transdermal rotigotine patch was selected as a treatment. This treatment dose-dependently improved the patient's symptoms. The transdermal drug delivery should be considered when patients show dose failure due to malabsorption. SN - 1757-790X UR - https://www.unboundmedicine.com/medline/citation/29909386/Transdermal_rotigotine_patch_in_Parkinson's_disease_with_a_history_of_intestinal_operation L2 - https://casereports.bmj.com/cgi/pmidlookup?view=long&pmid=29909386 DB - PRIME DP - Unbound Medicine ER -