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The Medical Management of Gastro-Oesophageal Reflux Disease.
Inflamm Intest Dis 2016; 1(2):96-99II

Abstract

Background

Gastro-oesophageal reflux disease (GORD) is a common global phenomenon. It is associated with the backflow of gastric contents proximally, typically due to transient relaxations of the lower oesophageal sphincter. Various factors contribute to GORD, including obesity, smoking, alcohol and pregnancy. The primary concern of GORD is its association with the development over time of Barrett's oesophagus and, ultimately, oesophageal adenocarcinoma.

Summary

This review focuses on the various medical interventions that are useful in the treatment of GORD.

Key Messages

Various lifestyle interventions such as weight loss and smoking cessation are useful in the treatment of GORD. Medical therapy relies on the use of acid suppressants such as proton pump inhibitors and histamine H2 receptor antagonists.

Authors+Show Affiliations

Division of Gastroenterology and Hepatology, National University Hospital, Singapore.Division of Gastroenterology and Hepatology, National University Hospital, Singapore.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29922663

Citation

Sharma, Neel, and Khek Yu Ho. "The Medical Management of Gastro-Oesophageal Reflux Disease." Inflammatory Intestinal Diseases, vol. 1, no. 2, 2016, pp. 96-99.
Sharma N, Ho KY. The Medical Management of Gastro-Oesophageal Reflux Disease. Inflamm Intest Dis. 2016;1(2):96-99.
Sharma, N., & Ho, K. Y. (2016). The Medical Management of Gastro-Oesophageal Reflux Disease. Inflammatory Intestinal Diseases, 1(2), pp. 96-99. doi:10.1159/000446589.
Sharma N, Ho KY. The Medical Management of Gastro-Oesophageal Reflux Disease. Inflamm Intest Dis. 2016;1(2):96-99. PubMed PMID: 29922663.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Medical Management of Gastro-Oesophageal Reflux Disease. AU - Sharma,Neel, AU - Ho,Khek Yu, Y1 - 2016/06/03/ PY - 2016/04/11/received PY - 2016/04/29/accepted PY - 2018/6/21/entrez PY - 2016/7/1/pubmed PY - 2016/7/1/medline KW - Barrett's oesophagus KW - Gastro-oesophageal reflux disease KW - Lifestyle interventions KW - Medical therapy KW - Oesophageal adenocarcinoma SP - 96 EP - 99 JF - Inflammatory intestinal diseases JO - Inflamm Intest Dis VL - 1 IS - 2 N2 - Background: Gastro-oesophageal reflux disease (GORD) is a common global phenomenon. It is associated with the backflow of gastric contents proximally, typically due to transient relaxations of the lower oesophageal sphincter. Various factors contribute to GORD, including obesity, smoking, alcohol and pregnancy. The primary concern of GORD is its association with the development over time of Barrett's oesophagus and, ultimately, oesophageal adenocarcinoma. Summary: This review focuses on the various medical interventions that are useful in the treatment of GORD. Key Messages: Various lifestyle interventions such as weight loss and smoking cessation are useful in the treatment of GORD. Medical therapy relies on the use of acid suppressants such as proton pump inhibitors and histamine H2 receptor antagonists. SN - 2296-9365 UR - https://www.unboundmedicine.com/medline/citation/29922663/The_Medical_Management_of_Gastro_Oesophageal_Reflux_Disease_ L2 - https://www.karger.com?DOI=10.1159/000446589 DB - PRIME DP - Unbound Medicine ER -