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Sudden death from acute epiglottitis in a toddler.
Forensic Sci Med Pathol. 2018 12; 14(4):555-557.FS

Abstract

The bacterium Haemophilus influenzae type b (Hib) can cause severe and life-threatening infections such as epiglottitis and meningitis. The course of the disease can be very rapid, resulting in sudden death. The incidence of Hib-induced epiglottitis in children has declined since the introduction of vaccinations in countries where such vaccinations are routinely administered. We herein present a case involving a 2.5-year-old boy who died suddenly at home. He had developed acute-onset throat and abdominal pain and a high fever. Despite an emergency cricothyrotomy due to a complicated intubation because of a massively swollen epiglottis, the efforts to resuscitate the child were unsuccessful. He was a previously healthy toddler, but he had not yet been vaccinated. Microbiologic analysis revealed the pathogenic bacterium Hib. The main autopsy finding was acute epiglottitis with swelling and cherry-red coloring of the epiglottis. Postmortem cultures of the cerebrospinal fluid and heart blood also revealed Hib as the pathogenic agent. Acute pneumonia was also diagnosed microscopically. The present report describes a rare case of Hib-induced acute epiglottitis and presents the key findings of forensic investigations in this type of disease.

Authors+Show Affiliations

Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529, Hamburg, Germany. as.schroeder@uke.de.Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529, Hamburg, Germany.Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529, Hamburg, Germany.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

29926438

Citation

Schröder, Ann Sophie, et al. "Sudden Death From Acute Epiglottitis in a Toddler." Forensic Science, Medicine, and Pathology, vol. 14, no. 4, 2018, pp. 555-557.
Schröder AS, Edler C, Sperhake JP. Sudden death from acute epiglottitis in a toddler. Forensic Sci Med Pathol. 2018;14(4):555-557.
Schröder, A. S., Edler, C., & Sperhake, J. P. (2018). Sudden death from acute epiglottitis in a toddler. Forensic Science, Medicine, and Pathology, 14(4), 555-557. https://doi.org/10.1007/s12024-018-9992-8
Schröder AS, Edler C, Sperhake JP. Sudden Death From Acute Epiglottitis in a Toddler. Forensic Sci Med Pathol. 2018;14(4):555-557. PubMed PMID: 29926438.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sudden death from acute epiglottitis in a toddler. AU - Schröder,Ann Sophie, AU - Edler,Carolin, AU - Sperhake,Jan Peter, Y1 - 2018/06/20/ PY - 2018/05/23/accepted PY - 2018/6/22/pubmed PY - 2019/3/27/medline PY - 2018/6/22/entrez KW - Epiglottitis KW - Haemophilus influenzae type b KW - Hib KW - Sudden death KW - Vaccination SP - 555 EP - 557 JF - Forensic science, medicine, and pathology JO - Forensic Sci Med Pathol VL - 14 IS - 4 N2 - The bacterium Haemophilus influenzae type b (Hib) can cause severe and life-threatening infections such as epiglottitis and meningitis. The course of the disease can be very rapid, resulting in sudden death. The incidence of Hib-induced epiglottitis in children has declined since the introduction of vaccinations in countries where such vaccinations are routinely administered. We herein present a case involving a 2.5-year-old boy who died suddenly at home. He had developed acute-onset throat and abdominal pain and a high fever. Despite an emergency cricothyrotomy due to a complicated intubation because of a massively swollen epiglottis, the efforts to resuscitate the child were unsuccessful. He was a previously healthy toddler, but he had not yet been vaccinated. Microbiologic analysis revealed the pathogenic bacterium Hib. The main autopsy finding was acute epiglottitis with swelling and cherry-red coloring of the epiglottis. Postmortem cultures of the cerebrospinal fluid and heart blood also revealed Hib as the pathogenic agent. Acute pneumonia was also diagnosed microscopically. The present report describes a rare case of Hib-induced acute epiglottitis and presents the key findings of forensic investigations in this type of disease. SN - 1556-2891 UR - https://www.unboundmedicine.com/medline/citation/29926438/Sudden_death_from_acute_epiglottitis_in_a_toddler_ L2 - https://dx.doi.org/10.1007/s12024-018-9992-8 DB - PRIME DP - Unbound Medicine ER -