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Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015.
Vasc Endovascular Surg. 2018 Oct; 52(7):520-526.VE

Abstract

BACKGROUND

The estimated global prevalence of Peripheral artery disease (PAD) increased by 24% in span of 10 years (2000-2010) from 164 to 202 million. Despite scarcity of data on PAD in sub-Saharan Africa (SSA) and the Caribbean, estimates for PAD from these regions may be helpful for health-care providers.

METHODS

The Global Burden of Disease Study 2015 quantified health loss from hundreds of diseases using systematic reviews and multilevel computer modeling. Estimated rates with 95% uncertainty intervals (UI) for PAD (ICD-10 I70.2) were examined for SSA and the Caribbean and compared to high-income North America (HINA). Disability-adjusted life years (DALYs) are years of healthy life lost representing total disease burden by combining years of life lost and years lived disabled.

RESULTS

In 2015, estimated age-standardized DALYs per 100,000 due to PAD for males were as follows: Caribbean (34, UI: 29-39), HINA (36, UI: 30-42), and SSA (20, UI: 14-30). In contrast, DALYs in females were as follows: Caribbean (25, UI: 20-30), HINA (28, UI: 22-36), and SSA (17, UI: 11-26). For both sexes combined, the rate in Southern SSA was 55 (46-67). This reflects the extremely high rates in South Africa (males 90, UI: 77-107; females 63, UI: 53-75).

CONCLUSION

Estimated rate of DALYs per 100,000 was lowest in SSA. Within SSA, the rate in South Africa was highest, exceeding even HINA. Caribbean rates were intermediate.

Authors+Show Affiliations

1 Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.1 Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.2 Department of Surgery, Howard University College of Medicine, Washington, DC, USA.3 Department of Internal Medicine, Howard University College of Medicine, Washington, DC, USA.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

29945494

Citation

Ganta, Nitheesha, et al. "Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015." Vascular and Endovascular Surgery, vol. 52, no. 7, 2018, pp. 520-526.
Ganta N, Soherwadi S, Hughes K, et al. Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015. Vasc Endovascular Surg. 2018;52(7):520-526.
Ganta, N., Soherwadi, S., Hughes, K., & Gillum, R. F. (2018). Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015. Vascular and Endovascular Surgery, 52(7), 520-526. https://doi.org/10.1177/1538574418784709
Ganta N, et al. Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015. Vasc Endovascular Surg. 2018;52(7):520-526. PubMed PMID: 29945494.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Burden of Peripheral Artery Disease in Sub-Saharan Africa and the Caribbean 1990 to 2015. AU - Ganta,Nitheesha, AU - Soherwadi,Shahabuddin, AU - Hughes,Kakra, AU - Gillum,Richard F, Y1 - 2018/06/26/ PY - 2018/6/28/pubmed PY - 2018/11/6/medline PY - 2018/6/28/entrez KW - Caribbean KW - High-income KW - Peripheral artery disease KW - Sub-Saharan Africa SP - 520 EP - 526 JF - Vascular and endovascular surgery JO - Vasc Endovascular Surg VL - 52 IS - 7 N2 - BACKGROUND: The estimated global prevalence of Peripheral artery disease (PAD) increased by 24% in span of 10 years (2000-2010) from 164 to 202 million. Despite scarcity of data on PAD in sub-Saharan Africa (SSA) and the Caribbean, estimates for PAD from these regions may be helpful for health-care providers. METHODS: The Global Burden of Disease Study 2015 quantified health loss from hundreds of diseases using systematic reviews and multilevel computer modeling. Estimated rates with 95% uncertainty intervals (UI) for PAD (ICD-10 I70.2) were examined for SSA and the Caribbean and compared to high-income North America (HINA). Disability-adjusted life years (DALYs) are years of healthy life lost representing total disease burden by combining years of life lost and years lived disabled. RESULTS: In 2015, estimated age-standardized DALYs per 100,000 due to PAD for males were as follows: Caribbean (34, UI: 29-39), HINA (36, UI: 30-42), and SSA (20, UI: 14-30). In contrast, DALYs in females were as follows: Caribbean (25, UI: 20-30), HINA (28, UI: 22-36), and SSA (17, UI: 11-26). For both sexes combined, the rate in Southern SSA was 55 (46-67). This reflects the extremely high rates in South Africa (males 90, UI: 77-107; females 63, UI: 53-75). CONCLUSION: Estimated rate of DALYs per 100,000 was lowest in SSA. Within SSA, the rate in South Africa was highest, exceeding even HINA. Caribbean rates were intermediate. SN - 1938-9116 UR - https://www.unboundmedicine.com/medline/citation/29945494/Burden_of_Peripheral_Artery_Disease_in_Sub_Saharan_Africa_and_the_Caribbean_1990_to_2015_ L2 - https://journals.sagepub.com/doi/10.1177/1538574418784709?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -