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Alternating Current Iontophoresis for Control of Postoperative Pain.

Abstract

Control of early postoperative pain entails the use of various medications including acetaminophen, nonsteroidal anti-inflammatory drugs, selective cyclooxygenase-2 inhibitors, tramadol, and opioids. However, these medications should be carefully administered in patients with aspirin-exacerbated respiratory disease because some medications may trigger adverse reactions after maxillofacial surgeries. The goal of postoperative pain control in patients with aspirin-exacerbated respiratory disease is to eliminate pain without complications. Local anesthesia is an efficient tool for the control of postoperative pain after maxillofacial surgeries. We utilized a transdermal drug delivery system, iontophoresis by alternating current, in order to develop an alternative technique for administering local anesthetic to control postoperative pain in 2 patients with aspirin-exacerbated respiratory disease. A visual analogue scale was used to objectively measure the severity of pain. A 55-year-old woman who underwent mandibular wisdom tooth extraction and an 18-year-old woman who underwent sagittal split ramus osteotomy of the mandible both complained of pain multiple times. After application of iontophoresis, the visual analogue scale score was reduced to zero and postoperative pain could be controlled. There were no adverse events such as bronchospasm or skin irritation after the application of iontophoresis by alternating current.

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  • Authors+Show Affiliations

    ,

    Section of Anesthesiology and Clinical Physiology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

    ,

    Section of Anesthesiology and Clinical Physiology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

    ,

    Section of Anesthesiology and Clinical Physiology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

    Section of Anesthesiology and Clinical Physiology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

    Source

    Anesthesia progress 65:2 2018 pg 106-110

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    29952652

    Citation

    TY - JOUR T1 - Alternating Current Iontophoresis for Control of Postoperative Pain. AU - Kubota,Kazumasa, AU - Miyamoto,Tomoyuki, AU - Inoue,Takutoshi, AU - Fukayama,Haruhisa, PY - 2018/6/29/entrez PY - 2018/6/29/pubmed PY - 2018/6/29/medline KW - Aspirin-exacerbated respiratory disease KW - Maxillofacial surgery KW - Postoperative pain KW - Transdermal drug transport SP - 106 EP - 110 JF - Anesthesia progress JO - Anesth Prog VL - 65 IS - 2 N2 - Control of early postoperative pain entails the use of various medications including acetaminophen, nonsteroidal anti-inflammatory drugs, selective cyclooxygenase-2 inhibitors, tramadol, and opioids. However, these medications should be carefully administered in patients with aspirin-exacerbated respiratory disease because some medications may trigger adverse reactions after maxillofacial surgeries. The goal of postoperative pain control in patients with aspirin-exacerbated respiratory disease is to eliminate pain without complications. Local anesthesia is an efficient tool for the control of postoperative pain after maxillofacial surgeries. We utilized a transdermal drug delivery system, iontophoresis by alternating current, in order to develop an alternative technique for administering local anesthetic to control postoperative pain in 2 patients with aspirin-exacerbated respiratory disease. A visual analogue scale was used to objectively measure the severity of pain. A 55-year-old woman who underwent mandibular wisdom tooth extraction and an 18-year-old woman who underwent sagittal split ramus osteotomy of the mandible both complained of pain multiple times. After application of iontophoresis, the visual analogue scale score was reduced to zero and postoperative pain could be controlled. There were no adverse events such as bronchospasm or skin irritation after the application of iontophoresis by alternating current. SN - 1878-7177 UR - https://www.unboundmedicine.com/medline/citation/29952652/Alternating_Current_Iontophoresis_for_Control_of_Postoperative_Pain L2 - http://www.anesthesiaprogress.org/doi/10.2344/anpr-64-04-03?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed ER -