TY - JOUR T1 - Molecular confirmation and anthelmintic efficacy assessment against natural trichurid infections in zoo-housed non-human primates. AU - Moudgil,Aman Dev, AU - Singla,Lachhman Das, Y1 - 2018/07/06/ PY - 2018/06/04/accepted PY - 2018/7/7/pubmed PY - 2019/10/15/medline PY - 2018/7/7/entrez KW - Trichuris KW - fenbendazole KW - ivermectin KW - non-human primates KW - polymerase chain reaction KW - resistance SP - 388 EP - 392 JF - Journal of medical primatology JO - J Med Primatol VL - 47 IS - 6 N2 - INTRODUCTION: This study aimed to assess Trichuris species infection and evaluate the anthelmintic efficacy of fenbendazole and ivermectin against natural trichurid infections in non-human primates (NHPs), kept at Mahendra Chaudhury (MC) Zoological Park, Chhatbir, India. MATERIALS AND METHODS: Molecular confirmation of Trichuris infection was carried out using polymerase chain reaction targeting internal transcribed spacer sequences, and anthelmintic efficacy was assessed by fecal egg count reduction test, respectively. RESULTS: A 710 base pair product confirmed Trichuris species infection in NHPs. Fenbendazole, 10 mg/kg body weight orally for 5 consecutive days and ivermectin, 100 μg/kg body weight orally for 3 alternate days proved effective and showed a maximum fecal egg reduction of 99.20% and 100% (P < .05) at day 7 post-treatment. CONCLUSIONS: This study highlighted the molecular confirmation of Trichuris species in non-human primates and its management using fenbendazole and ivermectin. SN - 1600-0684 UR - https://www.unboundmedicine.com/medline/citation/29979810/Molecular_confirmation_and_anthelmintic_efficacy_assessment_against_natural_trichurid_infections_in_zoo_housed_non_human_primates_ L2 - https://doi.org/10.1111/jmp.12358 DB - PRIME DP - Unbound Medicine ER -