Tags

Type your tag names separated by a space and hit enter

Role of Morin in Neurodegenerative Diseases: A Review.
Curr Top Med Chem. 2018; 18(11):901-907.CT

Abstract

Neurodegenerative diseases are likely to emerge as the second cause of mortality in the world in coming years. NDDs cause tremendous financial burden on the healthcare system along with profound effect on families and patient. Disease-modifying treatment strategies with proven efficacy for these disorders are still lacking. Documentation proved that oxidative stress plays a leading role in the pathophysiology of many neurodegenerative disorders. Molecules with good antioxidant profile could be explored for the doctoring of these conditions. Neuroprotective effects of bioflavonoid morin have been well recognized in the literature. Morin being super antioxidant compound helped in preventing and curing these disorders by suppression of ROS and by inhibition of multiple targets. In this review, we tried to explain various neuropathological conditions with their target sites and neurobiological mechanisms of morin.

Authors+Show Affiliations

Hindu College of Pharmacy, Sonepat, Haryana, India.Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Campus Vida, 15782 Santiago de Compostela, Spain. Instituto de Investigación e Innovación en Salud, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago, Chile.Faculty of Pharmaceutical Sciences, M. D. University, Rohtak, Haryana 124001, India.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

29992884

Citation

Kataria, Ritu, et al. "Role of Morin in Neurodegenerative Diseases: a Review." Current Topics in Medicinal Chemistry, vol. 18, no. 11, 2018, pp. 901-907.
Kataria R, Sobarzo-Sanchez E, Khatkar A. Role of Morin in Neurodegenerative Diseases: A Review. Curr Top Med Chem. 2018;18(11):901-907.
Kataria, R., Sobarzo-Sanchez, E., & Khatkar, A. (2018). Role of Morin in Neurodegenerative Diseases: A Review. Current Topics in Medicinal Chemistry, 18(11), 901-907. https://doi.org/10.2174/1568026618666180711153416
Kataria R, Sobarzo-Sanchez E, Khatkar A. Role of Morin in Neurodegenerative Diseases: a Review. Curr Top Med Chem. 2018;18(11):901-907. PubMed PMID: 29992884.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of Morin in Neurodegenerative Diseases: A Review. AU - Kataria,Ritu, AU - Sobarzo-Sanchez,Eduardo, AU - Khatkar,Anurag, PY - 2018/05/16/received PY - 2018/06/02/revised PY - 2018/06/28/accepted PY - 2018/7/12/pubmed PY - 2018/9/13/medline PY - 2018/7/12/entrez KW - Alzheimer`s disease KW - Flavonoid KW - Herbal KW - Morin KW - Neurodegenerative disease KW - Polyphenolic compound. SP - 901 EP - 907 JF - Current topics in medicinal chemistry JO - Curr Top Med Chem VL - 18 IS - 11 N2 - Neurodegenerative diseases are likely to emerge as the second cause of mortality in the world in coming years. NDDs cause tremendous financial burden on the healthcare system along with profound effect on families and patient. Disease-modifying treatment strategies with proven efficacy for these disorders are still lacking. Documentation proved that oxidative stress plays a leading role in the pathophysiology of many neurodegenerative disorders. Molecules with good antioxidant profile could be explored for the doctoring of these conditions. Neuroprotective effects of bioflavonoid morin have been well recognized in the literature. Morin being super antioxidant compound helped in preventing and curing these disorders by suppression of ROS and by inhibition of multiple targets. In this review, we tried to explain various neuropathological conditions with their target sites and neurobiological mechanisms of morin. SN - 1873-4294 UR - https://www.unboundmedicine.com/medline/citation/29992884/Role_of_Morin_in_Neurodegenerative_Diseases:_A_Review_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1568-0266&volume=18&issue=11&spage=901&aulast=Kataria DB - PRIME DP - Unbound Medicine ER -