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Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps.
Int Tinnitus J. 2018 Jun 01; 22(1):89-92.IT

Abstract

OBJECTIVES

Chronic rhinosinusitis (CRS) is characterized by a long-time inflammatory disease of nasal and sinus mucosa. Olfactory dysfunction is common among CRS patients with a prevalence ranging from 48% to 83%. We aimed to assess the effect of ESS on olfactory function of patients with chronic rhinosinusitis without nasal polyps.

METHOD

This randomized clinical trial was conducted on 30 patients with chronic rhinosinusitis without nasal polyps. Patients were randomly allocated to two intervention and control groups; patients in intervention group underwent endoscopic sinus surgery by a single surgeon and control group continued standard treatment with nasal irrigation of normal saline (4 times daily) and nasal corticosteroids (one puff in each nostril daily). Olfactory threshold was evaluated using smell threshold test (STT) before, one month and three months after intervention.

RESULTS

Eventually 33 patients with a mean age of 42.70 ± 15.50 years in intervention and 43.12 ± 11.50 years in control group underwent analysis (p value=0.930). Mean olfactory threshold was 2.79 ± 0.73 in intervention and 2.67 ± 1.05 in control group prior to intervention (p value=0.345). Mean change of olfactory threshold was 0.30 ± 0.79 in intervention and 0.38±1.09 in control group one month after intervention (p value=0.214). Mean change of olfactory threshold was 0.13 ± 0.94 in ESS and 0.33 ± 0.60 in control group three months after intervention (p value=0.196).

CONCLUSION

Our study revealed that changes in olfactory threshold were not significantly different between two ESS and standard medical therapy groups one and three months after intervention.

Authors+Show Affiliations

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran. International Otorhinolaryngology Research Association (IORA), Universal Scientiic Education and Research Network (USERN), Tehran, Iran.Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran.International Otorhinolaryngology Research Association (IORA), Universal Scientiic Education and Research Network (USERN), Tehran, Iran. Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

29993224

Citation

Yousefi, Jaleh, et al. "Effect of ESS On Olfactory Threshold of Patients With CRS Without Nasal Polyps." The International Tinnitus Journal, vol. 22, no. 1, 2018, pp. 89-92.
Yousefi J, Madarshahi H, Akhavan A, et al. Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps. Int Tinnitus J. 2018;22(1):89-92.
Yousefi, J., Madarshahi, H., Akhavan, A., Taheri, A., Saeedi, M., Bagherihagh, A., Hosseini, M. A., & Khosravi, M. H. (2018). Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps. The International Tinnitus Journal, 22(1), 89-92. https://doi.org/10.5935/0946-5448.20180015
Yousefi J, et al. Effect of ESS On Olfactory Threshold of Patients With CRS Without Nasal Polyps. Int Tinnitus J. 2018 Jun 1;22(1):89-92. PubMed PMID: 29993224.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of ESS on Olfactory Threshold of Patients with CRS without Nasal Polyps. AU - Yousefi,Jaleh, AU - Madarshahi,Hojat, AU - Akhavan,Asghar, AU - Taheri,Abolfazl, AU - Saeedi,Masoumeh, AU - Bagherihagh,Ali, AU - Hosseini,Mohammad Ali, AU - Khosravi,Mohammad Hossein, Y1 - 2018/06/01/ PY - 2018/7/12/entrez PY - 2018/7/12/pubmed PY - 2019/3/12/medline KW - chronic rhinosinusitis KW - endoscopic sinus surgery KW - nasal polyps KW - olfaction KW - olfactory threshold SP - 89 EP - 92 JF - The international tinnitus journal JO - Int Tinnitus J VL - 22 IS - 1 N2 - OBJECTIVES: Chronic rhinosinusitis (CRS) is characterized by a long-time inflammatory disease of nasal and sinus mucosa. Olfactory dysfunction is common among CRS patients with a prevalence ranging from 48% to 83%. We aimed to assess the effect of ESS on olfactory function of patients with chronic rhinosinusitis without nasal polyps. METHOD: This randomized clinical trial was conducted on 30 patients with chronic rhinosinusitis without nasal polyps. Patients were randomly allocated to two intervention and control groups; patients in intervention group underwent endoscopic sinus surgery by a single surgeon and control group continued standard treatment with nasal irrigation of normal saline (4 times daily) and nasal corticosteroids (one puff in each nostril daily). Olfactory threshold was evaluated using smell threshold test (STT) before, one month and three months after intervention. RESULTS: Eventually 33 patients with a mean age of 42.70 ± 15.50 years in intervention and 43.12 ± 11.50 years in control group underwent analysis (p value=0.930). Mean olfactory threshold was 2.79 ± 0.73 in intervention and 2.67 ± 1.05 in control group prior to intervention (p value=0.345). Mean change of olfactory threshold was 0.30 ± 0.79 in intervention and 0.38±1.09 in control group one month after intervention (p value=0.214). Mean change of olfactory threshold was 0.13 ± 0.94 in ESS and 0.33 ± 0.60 in control group three months after intervention (p value=0.196). CONCLUSION: Our study revealed that changes in olfactory threshold were not significantly different between two ESS and standard medical therapy groups one and three months after intervention. SN - 0946-5448 UR - https://www.unboundmedicine.com/medline/citation/29993224/Effect_of_ESS_on_Olfactory_Threshold_of_Patients_with_CRS_without_Nasal_Polyps_ L2 - https://medlineplus.gov/sinusitis.html DB - PRIME DP - Unbound Medicine ER -