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Alatrofloxacin

Abstract
No information is available on the clinical use of alatrofloxacin during breastfeeding. Fluoroquinolones have traditionally not been used in infants because of concern about adverse effects on the infants' developing joints. However, recent studies indicate little risk.[1][2] The calcium in milk might prevent absorption of the small amounts of fluoroquinolones in milk,[3] but insufficient data exist to prove or disprove this assertion. Use of alatrofloxacin is acceptable in nursing mothers with monitoring of the infant for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash). However, it is preferable to use an alternate drug for which safety information is available.

Publisher

National Library of Medicine (US)
Bethesda (MD)

Language

eng

PubMed ID

30000435

Citation

Alatrofloxacin.Drugs and Lactation Database (LactMed). National Library of Medicine (US), 2006, Bethesda (MD).
Alatrofloxacin. Drugs and Lactation Database (LactMed). Bethesda (MD): National Library of Medicine (US); 2006.
(2006). Alatrofloxacin. In Drugs and Lactation Database (LactMed). Bethesda (MD): National Library of Medicine (US);
Drugs and Lactation Database (LactMed). Bethesda (MD): National Library of Medicine (US); 2006.
* Article titles in AMA citation format should be in sentence-case
TY - CHAP T1 - Alatrofloxacin BT - Drugs and Lactation Database (LactMed) Y1 - 2006/// PY - 2018/7/13/pubmed PY - 2018/7/13/medline PY - 2018/7/13/entrez N2 - No information is available on the clinical use of alatrofloxacin during breastfeeding. Fluoroquinolones have traditionally not been used in infants because of concern about adverse effects on the infants' developing joints. However, recent studies indicate little risk.[1][2] The calcium in milk might prevent absorption of the small amounts of fluoroquinolones in milk,[3] but insufficient data exist to prove or disprove this assertion. Use of alatrofloxacin is acceptable in nursing mothers with monitoring of the infant for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash). However, it is preferable to use an alternate drug for which safety information is available. PB - National Library of Medicine (US) CY - Bethesda (MD) UR - https://www.unboundmedicine.com/medline/citation/30000435/Drugs_and_Lactation_Database_(LactMed):_Alatrofloxacin L2 - https://www.ncbi.nlm.nih.gov/books/NBK501376 DB - PRIME DP - Unbound Medicine ER -
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