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'Transformation' from amyloid light chain amyloidosis to symptomatic multiple myeloma.
Neth J Med. 2018 07; 76(5):249-250.NJ

Abstract

Amyloid light chain (AL) amyloidosis and multiple myeloma (MM) are both clonal plasma cell disorders, and may be concurrently present in patients. However, symptomatic MM seldom develops in patients with AL amyloidosis, while the other way around is common. With this case report, we discuss the difficulties in the differential diagnosis between AL amyloidosis and MM, and extend on the possible mechanisms involved in the development of these overlapping disorders. In addition, we provide clinicians with tools that may help improve their management and monitoring of such patients.

Authors+Show Affiliations

Department of Haematology, UMC Utrecht Cancer Center, Utrecht, the Netherlands.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

30019681

Citation

Rutten, K H G., et al. "'Transformation' From Amyloid Light Chain Amyloidosis to Symptomatic Multiple Myeloma." The Netherlands Journal of Medicine, vol. 76, no. 5, 2018, pp. 249-250.
Rutten KHG, Raymakers RAP, Minnema MC. 'Transformation' from amyloid light chain amyloidosis to symptomatic multiple myeloma. Neth J Med. 2018;76(5):249-250.
Rutten, K. H. G., Raymakers, R. A. P., & Minnema, M. C. (2018). 'Transformation' from amyloid light chain amyloidosis to symptomatic multiple myeloma. The Netherlands Journal of Medicine, 76(5), 249-250.
Rutten KHG, Raymakers RAP, Minnema MC. 'Transformation' From Amyloid Light Chain Amyloidosis to Symptomatic Multiple Myeloma. Neth J Med. 2018;76(5):249-250. PubMed PMID: 30019681.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 'Transformation' from amyloid light chain amyloidosis to symptomatic multiple myeloma. AU - Rutten,K H G, AU - Raymakers,R A P, AU - Minnema,M C, PY - 2018/7/19/entrez PY - 2018/7/19/pubmed PY - 2019/10/11/medline SP - 249 EP - 250 JF - The Netherlands journal of medicine JO - Neth J Med VL - 76 IS - 5 N2 - Amyloid light chain (AL) amyloidosis and multiple myeloma (MM) are both clonal plasma cell disorders, and may be concurrently present in patients. However, symptomatic MM seldom develops in patients with AL amyloidosis, while the other way around is common. With this case report, we discuss the difficulties in the differential diagnosis between AL amyloidosis and MM, and extend on the possible mechanisms involved in the development of these overlapping disorders. In addition, we provide clinicians with tools that may help improve their management and monitoring of such patients. SN - 1872-9061 UR - https://www.unboundmedicine.com/medline/citation/30019681/'Transformation'_from_amyloid_light_chain_amyloidosis_to_symptomatic_multiple_myeloma_ L2 - http://www.njmonline.nl/njm/getarticle.php?v=76&i=5&p=249 DB - PRIME DP - Unbound Medicine ER -