Tags

Type your tag names separated by a space and hit enter

Bringing order to higher order motor disorders.
J Neurol 2019; 266(4):797-805JN

Abstract

Majority of movements in everyday situations are complex and involve volition, planning of the movement and selection of the motor programme, all occurring before movement execution. Higher order motor disorders may be defined as abnormal motor behaviours resulting from disruption of any of the cortical processes that precede execution of the motor act. They are common in patients with neurodegenerative disorders, psychiatric diseases and structural brain lesions. These abnormal behaviours may be overlooked in the clinic, unless specifically evoked by the examiner. We discuss clinical and pathophysiological aspects of higher order motor disorders including: (1) disorders of disinhibition, such as grasp reflex and grasping behaviour, utilisation and imitation behaviour, motor preservations and paratonia; (2) disorders of motor intention such as motor neglect and motor impersistence; (3) alien limb syndrome; and (4) motor overflow phenomena, such as mirror movements and synkinesias. A video illustration of each phenomenon is provided. We place the findings from recent neurophysiological studies within the framework of theories of motor control to provide better insight into pathophysiology of different disorders.

Authors+Show Affiliations

Department of Neurology, University Medical Centre Ljubljana, Zaloška 2, 1000, Ljubljana, Slovenia. maja.kojovic@kclj.si.Institute of Neurology, University College London, 7 Queen Square, London, WC1N 3BG, UK.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

30027322

Citation

Kojović, Maja, and Kailash P. Bhatia. "Bringing Order to Higher Order Motor Disorders." Journal of Neurology, vol. 266, no. 4, 2019, pp. 797-805.
Kojović M, Bhatia KP. Bringing order to higher order motor disorders. J Neurol. 2019;266(4):797-805.
Kojović, M., & Bhatia, K. P. (2019). Bringing order to higher order motor disorders. Journal of Neurology, 266(4), pp. 797-805. doi:10.1007/s00415-018-8974-9.
Kojović M, Bhatia KP. Bringing Order to Higher Order Motor Disorders. J Neurol. 2019;266(4):797-805. PubMed PMID: 30027322.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bringing order to higher order motor disorders. AU - Kojović,Maja, AU - Bhatia,Kailash P, Y1 - 2018/07/19/ PY - 2018/06/01/received PY - 2018/07/07/accepted PY - 2018/07/06/revised PY - 2018/7/22/pubmed PY - 2019/6/30/medline PY - 2018/7/21/entrez KW - Alien limb KW - Frontal lobe syndromes KW - Mirror movements KW - Motor impersistence KW - Motor neglect KW - Paratonia SP - 797 EP - 805 JF - Journal of neurology JO - J. Neurol. VL - 266 IS - 4 N2 - Majority of movements in everyday situations are complex and involve volition, planning of the movement and selection of the motor programme, all occurring before movement execution. Higher order motor disorders may be defined as abnormal motor behaviours resulting from disruption of any of the cortical processes that precede execution of the motor act. They are common in patients with neurodegenerative disorders, psychiatric diseases and structural brain lesions. These abnormal behaviours may be overlooked in the clinic, unless specifically evoked by the examiner. We discuss clinical and pathophysiological aspects of higher order motor disorders including: (1) disorders of disinhibition, such as grasp reflex and grasping behaviour, utilisation and imitation behaviour, motor preservations and paratonia; (2) disorders of motor intention such as motor neglect and motor impersistence; (3) alien limb syndrome; and (4) motor overflow phenomena, such as mirror movements and synkinesias. A video illustration of each phenomenon is provided. We place the findings from recent neurophysiological studies within the framework of theories of motor control to provide better insight into pathophysiology of different disorders. SN - 1432-1459 UR - https://www.unboundmedicine.com/medline/citation/30027322/Bringing_order_to_higher_order_motor_disorders L2 - https://dx.doi.org/10.1007/s00415-018-8974-9 DB - PRIME DP - Unbound Medicine ER -