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Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy-related postinflammatory hyperpigmentation.
Dermatol Ther. 2018 09; 31(5):e12657.DT

Abstract

Brimonidine gel, originally approved for the treatment of facial rosacea, causes direct vasoconstriction and possesses extensive utilization in dermatologic fields. A Q-switched (QS) neodymium-doped yttrium aluminum garnet (Nd:YAG) laser is generally used to treat solar lentigo (SL), often leaving unwanted postinflammatory hyperpigmentation (PIH), especially in dark-skinned individuals. A 58-year-old man with Fitzpatrick skin type IV presented to remove solar lentigines from his face. Prior to and after laser treatment, topical brimonidine gel and steroid cream were applied. In this study, we investigated whether topical application of the α-adrenergic receptor agonist brimonidine could reduce PIH after QS laser treatment of lentigine in a dark-skinned patient.

Authors+Show Affiliations

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.Louis Dermatologic Clinic, Gyeonggi-do, South Korea.Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30028559

Citation

Hong, Ji Yeon, et al. "Brimonidine Tartrate Gel Plus Topical Steroid for the Prevention of Laser Therapy-related Postinflammatory Hyperpigmentation." Dermatologic Therapy, vol. 31, no. 5, 2018, pp. e12657.
Hong JY, Lee HW, Park KY, et al. Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy-related postinflammatory hyperpigmentation. Dermatol Ther. 2018;31(5):e12657.
Hong, J. Y., Lee, H. W., Park, K. Y., Kim, B. J., & Kim, M. N. (2018). Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy-related postinflammatory hyperpigmentation. Dermatologic Therapy, 31(5), e12657. https://doi.org/10.1111/dth.12657
Hong JY, et al. Brimonidine Tartrate Gel Plus Topical Steroid for the Prevention of Laser Therapy-related Postinflammatory Hyperpigmentation. Dermatol Ther. 2018;31(5):e12657. PubMed PMID: 30028559.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Brimonidine tartrate gel plus topical steroid for the prevention of laser therapy-related postinflammatory hyperpigmentation. AU - Hong,Ji Yeon, AU - Lee,Hae Woong, AU - Park,Kui Young, AU - Kim,Beom Joon, AU - Kim,Myeung Nam, Y1 - 2018/07/20/ PY - 2017/12/13/received PY - 2018/03/18/revised PY - 2018/06/09/accepted PY - 2018/7/22/pubmed PY - 2019/3/14/medline PY - 2018/7/21/entrez KW - brimonidine KW - laser KW - postinflammatory hyperpigmentation SP - e12657 EP - e12657 JF - Dermatologic therapy JO - Dermatol Ther VL - 31 IS - 5 N2 - Brimonidine gel, originally approved for the treatment of facial rosacea, causes direct vasoconstriction and possesses extensive utilization in dermatologic fields. A Q-switched (QS) neodymium-doped yttrium aluminum garnet (Nd:YAG) laser is generally used to treat solar lentigo (SL), often leaving unwanted postinflammatory hyperpigmentation (PIH), especially in dark-skinned individuals. A 58-year-old man with Fitzpatrick skin type IV presented to remove solar lentigines from his face. Prior to and after laser treatment, topical brimonidine gel and steroid cream were applied. In this study, we investigated whether topical application of the α-adrenergic receptor agonist brimonidine could reduce PIH after QS laser treatment of lentigine in a dark-skinned patient. SN - 1529-8019 UR - https://www.unboundmedicine.com/medline/citation/30028559/Brimonidine_tartrate_gel_plus_topical_steroid_for_the_prevention_of_laser_therapy_related_postinflammatory_hyperpigmentation_ DB - PRIME DP - Unbound Medicine ER -