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[Changes in blood pressure and serum lipids with fish diets in patients with mild essential hypertension].
Z Gesamte Inn Med. 1986 Jan 15; 41(2):38-44.ZG

Abstract

14 male patients with moderate essential hypertension were treated in the cross-comparison with a mackerel and herring diet, respectively, for two weeks. The mackerel diet contained double as much eicosapentaenic (EPA) and docosahexaenic acid (DHA) as the herring diet which served as control. In the serum triglycerides particularly DHS, in the cholesterol esters above all EPA were enriched. In the phospholipids the increase of the two fatty acids was approximately the same. At the end of the mackerel period the serum triglycerides, the total and LDL-cholesterol, the activity of the lecithin-cholesterol-acyl-transferase (CALT) and the serum sodium were significantly decreased. On the other hand, the HDL-cholesterol and the uric acid in the serum significantly increased. Under influence of the herring diet the parameters mentioned appeared only slightly changed. After the mackerel diet also a significantly lower systolic blood pressure was found. The systolic and diastolic blood pressure during a standardized psychophysiological stress test was more diminished at the end of the mackerel period than after the herring diet. The plasma renin activity (PRA) was increased after the mackerel diet. Its increase under the stress test could no more be proved at the end of the mackerel diet. In similar way the stress-conditioned increase of thromboxane B2 could no more be observe both after mackerel and after herring diet. When the results should confirm themselves in long-term studies, a mackerel diet in practicable dosage can be recommended as non-medicamentous treatment of moderate hypertension.

Authors

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Pub Type(s)

Clinical Trial
Controlled Clinical Trial
English Abstract
Journal Article

Language

ger

PubMed ID

3006368

Citation

Singer, P, et al. "[Changes in Blood Pressure and Serum Lipids With Fish Diets in Patients With Mild Essential Hypertension]." Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete, vol. 41, no. 2, 1986, pp. 38-44.
Singer P, Wirth M, Mest HJ, et al. [Changes in blood pressure and serum lipids with fish diets in patients with mild essential hypertension]. Z Gesamte Inn Med. 1986;41(2):38-44.
Singer, P., Wirth, M., Mest, H. J., Taube, C., Richter-Heinrich, E., Gödicke, W., Hartrodt, W., Naumann, E., & Voigt, S. (1986). [Changes in blood pressure and serum lipids with fish diets in patients with mild essential hypertension]. Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete, 41(2), 38-44.
Singer P, et al. [Changes in Blood Pressure and Serum Lipids With Fish Diets in Patients With Mild Essential Hypertension]. Z Gesamte Inn Med. 1986 Jan 15;41(2):38-44. PubMed PMID: 3006368.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Changes in blood pressure and serum lipids with fish diets in patients with mild essential hypertension]. AU - Singer,P, AU - Wirth,M, AU - Mest,H J, AU - Taube,C, AU - Richter-Heinrich,E, AU - Gödicke,W, AU - Hartrodt,W, AU - Naumann,E, AU - Voigt,S, PY - 1986/1/15/pubmed PY - 1986/1/15/medline PY - 1986/1/15/entrez SP - 38 EP - 44 JF - Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete JO - Z Gesamte Inn Med VL - 41 IS - 2 N2 - 14 male patients with moderate essential hypertension were treated in the cross-comparison with a mackerel and herring diet, respectively, for two weeks. The mackerel diet contained double as much eicosapentaenic (EPA) and docosahexaenic acid (DHA) as the herring diet which served as control. In the serum triglycerides particularly DHS, in the cholesterol esters above all EPA were enriched. In the phospholipids the increase of the two fatty acids was approximately the same. At the end of the mackerel period the serum triglycerides, the total and LDL-cholesterol, the activity of the lecithin-cholesterol-acyl-transferase (CALT) and the serum sodium were significantly decreased. On the other hand, the HDL-cholesterol and the uric acid in the serum significantly increased. Under influence of the herring diet the parameters mentioned appeared only slightly changed. After the mackerel diet also a significantly lower systolic blood pressure was found. The systolic and diastolic blood pressure during a standardized psychophysiological stress test was more diminished at the end of the mackerel period than after the herring diet. The plasma renin activity (PRA) was increased after the mackerel diet. Its increase under the stress test could no more be proved at the end of the mackerel diet. In similar way the stress-conditioned increase of thromboxane B2 could no more be observe both after mackerel and after herring diet. When the results should confirm themselves in long-term studies, a mackerel diet in practicable dosage can be recommended as non-medicamentous treatment of moderate hypertension. SN - 0044-2542 UR - https://www.unboundmedicine.com/medline/citation/3006368/[Changes_in_blood_pressure_and_serum_lipids_with_fish_diets_in_patients_with_mild_essential_hypertension]_ L2 - http://www.diseaseinfosearch.org/result/8360 DB - PRIME DP - Unbound Medicine ER -