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Pilot study of the efficacy of spent grain dietary fiber in the treatment of constipation.
Isr J Med Sci. 1986 Jan; 22(1):12-5.IJ

Abstract

Spent grain is the crude fiber obtained by decanting the fermented distillate of barley. The spent grain was processed to yield dietary fiber composed of: cellulose and hemicellulose 65.6% (by weight), lignin 5.2%, pectin 2.2%, protein 10.9% and lipid 8.0%. Biscuits and scones were prepared by 25% substitution of wheat flour by fiber, yielding 7 to 8 g fiber per biscuit/scone. Nineteen ambulatory patients with chronic, laxative-dependent constipation were treated in a pilot study for 4 weeks with 20 to 25 g fiber daily. Fifteen patients (79%) showed improvement in some or all of five factors, while four patients were largely unresponsive to fiber. Specific symptoms improved as follows: bowel movement frequency in 15 patients (79%), flatulence in 12 (63%), abdominal pain in 10 (53%), stool consistency in 8 (42%) and laxative dependence in 14 (74%). A 4-week post-treatment follow-up showed a return to prefiber status in 11 of 13 improved subjects. This preliminary study suggests a role for spent grain fiber in the treatment of constipated patients, and a comparative study with placebo and wheat fiber is now warranted.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3007392

Citation

Odes, H S., et al. "Pilot Study of the Efficacy of Spent Grain Dietary Fiber in the Treatment of Constipation." Israel Journal of Medical Sciences, vol. 22, no. 1, 1986, pp. 12-5.
Odes HS, Madar Z, Trop M, et al. Pilot study of the efficacy of spent grain dietary fiber in the treatment of constipation. Isr J Med Sci. 1986;22(1):12-5.
Odes, H. S., Madar, Z., Trop, M., Namir, S., Gross, J., & Cohen, T. (1986). Pilot study of the efficacy of spent grain dietary fiber in the treatment of constipation. Israel Journal of Medical Sciences, 22(1), 12-5.
Odes HS, et al. Pilot Study of the Efficacy of Spent Grain Dietary Fiber in the Treatment of Constipation. Isr J Med Sci. 1986;22(1):12-5. PubMed PMID: 3007392.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pilot study of the efficacy of spent grain dietary fiber in the treatment of constipation. AU - Odes,H S, AU - Madar,Z, AU - Trop,M, AU - Namir,S, AU - Gross,J, AU - Cohen,T, PY - 1986/1/1/pubmed PY - 1986/1/1/medline PY - 1986/1/1/entrez SP - 12 EP - 5 JF - Israel journal of medical sciences JO - Isr J Med Sci VL - 22 IS - 1 N2 - Spent grain is the crude fiber obtained by decanting the fermented distillate of barley. The spent grain was processed to yield dietary fiber composed of: cellulose and hemicellulose 65.6% (by weight), lignin 5.2%, pectin 2.2%, protein 10.9% and lipid 8.0%. Biscuits and scones were prepared by 25% substitution of wheat flour by fiber, yielding 7 to 8 g fiber per biscuit/scone. Nineteen ambulatory patients with chronic, laxative-dependent constipation were treated in a pilot study for 4 weeks with 20 to 25 g fiber daily. Fifteen patients (79%) showed improvement in some or all of five factors, while four patients were largely unresponsive to fiber. Specific symptoms improved as follows: bowel movement frequency in 15 patients (79%), flatulence in 12 (63%), abdominal pain in 10 (53%), stool consistency in 8 (42%) and laxative dependence in 14 (74%). A 4-week post-treatment follow-up showed a return to prefiber status in 11 of 13 improved subjects. This preliminary study suggests a role for spent grain fiber in the treatment of constipated patients, and a comparative study with placebo and wheat fiber is now warranted. SN - 0021-2180 UR - https://www.unboundmedicine.com/medline/citation/3007392/Pilot_study_of_the_efficacy_of_spent_grain_dietary_fiber_in_the_treatment_of_constipation_ L2 - http://www.diseaseinfosearch.org/result/1885 DB - PRIME DP - Unbound Medicine ER -