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Adaptation of electrolyte transport in rat large intestine after proximal resection. I. Cecum and colon after 60% jejunoilectomy.
Pflugers Arch. 1986 Mar; 406(3):323-7.PA

Abstract

Electrolyte transport was studied in rat cecum and colon adapting to 60% resection of the small intestine. Four weeks after surgery, the absorbing gross surface area, dry and wet weight, net absorption in vivo of sodium, chloride and volume, net potassium secretion, transmural electrical potential difference and mucosal Na-K-ATPase specific activity were determined. In the cecum, all tissue mass parameters were increased compared to sham-operated controls. Net transport was stimulated per organ but not per unit mass, and potential difference and Na-K-ATPase remained unaffected. In the colon, surface area and wet weight increased slightly while dry weight and electrolyte transport were not influenced. Thus, by enlargement without a change in cell function, the cecum but not the colon contributes to electrolyte homoeostasis after 60% jejunoilectomy in the rat. Na-K-ATPase specific activity and electrical potential difference were higher in the colon than the cecum, suggesting segmental heterogeneity of the larger bowel with respect to Na-K-ATPase-linked active sodium absorption.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3008077

Citation

Loeschke, K, et al. "Adaptation of Electrolyte Transport in Rat Large Intestine After Proximal Resection. I. Cecum and Colon After 60% Jejunoilectomy." Pflugers Archiv : European Journal of Physiology, vol. 406, no. 3, 1986, pp. 323-7.
Loeschke K, Fabritius H, Welter HF. Adaptation of electrolyte transport in rat large intestine after proximal resection. I. Cecum and colon after 60% jejunoilectomy. Pflugers Arch. 1986;406(3):323-7.
Loeschke, K., Fabritius, H., & Welter, H. F. (1986). Adaptation of electrolyte transport in rat large intestine after proximal resection. I. Cecum and colon after 60% jejunoilectomy. Pflugers Archiv : European Journal of Physiology, 406(3), 323-7.
Loeschke K, Fabritius H, Welter HF. Adaptation of Electrolyte Transport in Rat Large Intestine After Proximal Resection. I. Cecum and Colon After 60% Jejunoilectomy. Pflugers Arch. 1986;406(3):323-7. PubMed PMID: 3008077.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adaptation of electrolyte transport in rat large intestine after proximal resection. I. Cecum and colon after 60% jejunoilectomy. AU - Loeschke,K, AU - Fabritius,H, AU - Welter,H F, PY - 1986/3/1/pubmed PY - 1986/3/1/medline PY - 1986/3/1/entrez SP - 323 EP - 7 JF - Pflugers Archiv : European journal of physiology JO - Pflugers Arch. VL - 406 IS - 3 N2 - Electrolyte transport was studied in rat cecum and colon adapting to 60% resection of the small intestine. Four weeks after surgery, the absorbing gross surface area, dry and wet weight, net absorption in vivo of sodium, chloride and volume, net potassium secretion, transmural electrical potential difference and mucosal Na-K-ATPase specific activity were determined. In the cecum, all tissue mass parameters were increased compared to sham-operated controls. Net transport was stimulated per organ but not per unit mass, and potential difference and Na-K-ATPase remained unaffected. In the colon, surface area and wet weight increased slightly while dry weight and electrolyte transport were not influenced. Thus, by enlargement without a change in cell function, the cecum but not the colon contributes to electrolyte homoeostasis after 60% jejunoilectomy in the rat. Na-K-ATPase specific activity and electrical potential difference were higher in the colon than the cecum, suggesting segmental heterogeneity of the larger bowel with respect to Na-K-ATPase-linked active sodium absorption. SN - 0031-6768 UR - https://www.unboundmedicine.com/medline/citation/3008077/Adaptation_of_electrolyte_transport_in_rat_large_intestine_after_proximal_resection__I__Cecum_and_colon_after_60_jejunoilectomy_ DB - PRIME DP - Unbound Medicine ER -