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Guillain-Barré syndrome hyponatremia: is it SIADH or pseudohyponatremia?
Oxf Med Case Reports 2018; 2018(7):omy042OM

Abstract

Approximately 5% of hospitalized patients with Guillain-Barré syndrome (GBS) experience SIADH; but pseudohyponatremia has also been reported in patients treated with IVIG. We present a case of a 51-year-old male with GBS who developed acute hyponatremia the day after initiation of IVIG; his sodium levels began to improve within 24 h of completion of IVIG. Differentiating between pseudohyponatremia caused by the IVIG treatment and SIADH caused by GBS was the key to successfully treating this patient. This case exemplifies the importance of pursuing further studies to determine the exact cause of hyponatremia in GBS in order to prevent further neurologic damage to the patient.

Authors+Show Affiliations

College of Medicine, The Ohio State University, Columbus, OH, USA.College of Medicine, The Ohio State University, Columbus, OH, USA.Department of Internal Medicine-Pediatrics, The Ohio State University Wexner Medical Center, Columbus, OH, USA.Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

30090635

Citation

Zemke, Anna M., et al. "Guillain-Barré Syndrome Hyponatremia: Is It SIADH or Pseudohyponatremia?" Oxford Medical Case Reports, vol. 2018, no. 7, 2018, pp. omy042.
Zemke AM, Boles LH, Gillespie M, et al. Guillain-Barré syndrome hyponatremia: is it SIADH or pseudohyponatremia? Oxf Med Case Reports. 2018;2018(7):omy042.
Zemke, A. M., Boles, L. H., Gillespie, M., & Viljoen, J. M. (2018). Guillain-Barré syndrome hyponatremia: is it SIADH or pseudohyponatremia? Oxford Medical Case Reports, 2018(7), pp. omy042. doi:10.1093/omcr/omy042.
Zemke AM, et al. Guillain-Barré Syndrome Hyponatremia: Is It SIADH or Pseudohyponatremia. Oxf Med Case Reports. 2018;2018(7):omy042. PubMed PMID: 30090635.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Guillain-Barré syndrome hyponatremia: is it SIADH or pseudohyponatremia? AU - Zemke,Anna M, AU - Boles,Lindsay H, AU - Gillespie,Michelle, AU - Viljoen,Jill M, Y1 - 2018/07/27/ PY - 2018/03/05/received PY - 2018/04/27/revised PY - 2018/05/18/accepted PY - 2018/8/10/entrez PY - 2018/8/10/pubmed PY - 2018/8/10/medline SP - omy042 EP - omy042 JF - Oxford medical case reports JO - Oxf Med Case Reports VL - 2018 IS - 7 N2 - Approximately 5% of hospitalized patients with Guillain-Barré syndrome (GBS) experience SIADH; but pseudohyponatremia has also been reported in patients treated with IVIG. We present a case of a 51-year-old male with GBS who developed acute hyponatremia the day after initiation of IVIG; his sodium levels began to improve within 24 h of completion of IVIG. Differentiating between pseudohyponatremia caused by the IVIG treatment and SIADH caused by GBS was the key to successfully treating this patient. This case exemplifies the importance of pursuing further studies to determine the exact cause of hyponatremia in GBS in order to prevent further neurologic damage to the patient. SN - 2053-8855 UR - https://www.unboundmedicine.com/medline/citation/30090635/Guillain-Barré_syndrome_hyponatremia:_is_it_SIADH_or_pseudohyponatremia L2 - https://academic.oup.com/omcr/article-lookup/doi/10.1093/omcr/omy042 DB - PRIME DP - Unbound Medicine ER -