Tags

Type your tag names separated by a space and hit enter

10-year follow-up after laparoscopic sleeve gastrectomy: Outcomes in a monocentric series.
Surg Obes Relat Dis. 2018 Oct; 14(10):1480-1487.SO

Abstract

BACKGROUND

Sleeve gastrectomy (SG) has grown into the most popular bariatric operation. Nevertheless, a scarcity of long-term outcomes are available.

OBJECTIVES

This study aims at evaluating the long-term percent weight loss (%WL), excess weight loss (%EWL), weight regain (WR), and co-morbidity resolution rates in a single-center cohort undergoing SG as a primary procedure, with a minimum 10-year follow-up.

SETTING

University hospital, Italy.

METHODS

One hundred eighty-two morbidly obese patients with body mass index (BMI) 46.6 ± 7.3 kg/m2 underwent SG. Obesity-related co-morbidities (type 2 diabetes, hypertension, sleep apnea, gastroesophageal reflux disease) were investigated. Predictors of dichotomous dependent-variable diabetes remission were computed using a binomial logistic regression.

RESULTS

Patient retention rate was 77%. Mean %WL was 30.9, %EWL was 52.5%, and WR (≥25% maximum WL) occurred in 10.4%. Baseline BMI significantly (P = .001) and linearly predicted %EWL (10 yr %EWL = 18.951 + initial BMI × .74); the super-obese subgroup generated substantially greater WL compared with those with BMI <50 kg/m2 (%EWL 48.0 ± 18.5 versus 61.5 ± 23.2; P < .001). Type 2 diabetes remission occurred in 64.7%; 42.9% patients developed de novo gastroesophageal reflux disease symptoms postoperatively (P < .0001).

CONCLUSIONS

SG generates sustained WL and co-morbidity resolution up to 10 years postoperatively. Although a notable portion of patients experience WR, mean %WL persists to exceed 30%, translating in adequate WL also in the long term. Additionally, WR does not seem to impact negatively on co-morbidity resolution. SG represents a safe and effective bariatric operation, which easily grants the possibility to proceed to revisional bariatric surgery in patients with WR or failure to WL.

Authors+Show Affiliations

Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.Department of Systems Medicine Clinical Psychiatry Unit, University of Rome Tor Vergata, Rome, Italy.Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy.Department of Surgical Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: giovanni.casella@uniroma1.it.

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

30093311

Citation

Castagneto Gissey, Lidia, et al. "10-year Follow-up After Laparoscopic Sleeve Gastrectomy: Outcomes in a Monocentric Series." Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, vol. 14, no. 10, 2018, pp. 1480-1487.
Castagneto Gissey L, Casella Mariolo JR, Genco A, et al. 10-year follow-up after laparoscopic sleeve gastrectomy: Outcomes in a monocentric series. Surg Obes Relat Dis. 2018;14(10):1480-1487.
Castagneto Gissey, L., Casella Mariolo, J. R., Genco, A., Troisi, A., Basso, N., & Casella, G. (2018). 10-year follow-up after laparoscopic sleeve gastrectomy: Outcomes in a monocentric series. Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery, 14(10), 1480-1487. https://doi.org/10.1016/j.soard.2018.06.021
Castagneto Gissey L, et al. 10-year Follow-up After Laparoscopic Sleeve Gastrectomy: Outcomes in a Monocentric Series. Surg Obes Relat Dis. 2018;14(10):1480-1487. PubMed PMID: 30093311.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - 10-year follow-up after laparoscopic sleeve gastrectomy: Outcomes in a monocentric series. AU - Castagneto Gissey,Lidia, AU - Casella Mariolo,James R, AU - Genco,Alfredo, AU - Troisi,Alfonso, AU - Basso,Nicola, AU - Casella,Giovanni, Y1 - 2018/07/02/ PY - 2018/04/28/received PY - 2018/06/18/revised PY - 2018/06/26/accepted PY - 2018/8/11/pubmed PY - 2019/8/27/medline PY - 2018/8/11/entrez KW - Long-term outcomes KW - Revisional bariatric surgery KW - Sleeve gastrectomy KW - Weight regain SP - 1480 EP - 1487 JF - Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery JO - Surg Obes Relat Dis VL - 14 IS - 10 N2 - BACKGROUND: Sleeve gastrectomy (SG) has grown into the most popular bariatric operation. Nevertheless, a scarcity of long-term outcomes are available. OBJECTIVES: This study aims at evaluating the long-term percent weight loss (%WL), excess weight loss (%EWL), weight regain (WR), and co-morbidity resolution rates in a single-center cohort undergoing SG as a primary procedure, with a minimum 10-year follow-up. SETTING: University hospital, Italy. METHODS: One hundred eighty-two morbidly obese patients with body mass index (BMI) 46.6 ± 7.3 kg/m2 underwent SG. Obesity-related co-morbidities (type 2 diabetes, hypertension, sleep apnea, gastroesophageal reflux disease) were investigated. Predictors of dichotomous dependent-variable diabetes remission were computed using a binomial logistic regression. RESULTS: Patient retention rate was 77%. Mean %WL was 30.9, %EWL was 52.5%, and WR (≥25% maximum WL) occurred in 10.4%. Baseline BMI significantly (P = .001) and linearly predicted %EWL (10 yr %EWL = 18.951 + initial BMI × .74); the super-obese subgroup generated substantially greater WL compared with those with BMI <50 kg/m2 (%EWL 48.0 ± 18.5 versus 61.5 ± 23.2; P < .001). Type 2 diabetes remission occurred in 64.7%; 42.9% patients developed de novo gastroesophageal reflux disease symptoms postoperatively (P < .0001). CONCLUSIONS: SG generates sustained WL and co-morbidity resolution up to 10 years postoperatively. Although a notable portion of patients experience WR, mean %WL persists to exceed 30%, translating in adequate WL also in the long term. Additionally, WR does not seem to impact negatively on co-morbidity resolution. SG represents a safe and effective bariatric operation, which easily grants the possibility to proceed to revisional bariatric surgery in patients with WR or failure to WL. SN - 1878-7533 UR - https://www.unboundmedicine.com/medline/citation/30093311/10_year_follow_up_after_laparoscopic_sleeve_gastrectomy:_Outcomes_in_a_monocentric_series_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1550-7289(18)30367-8 DB - PRIME DP - Unbound Medicine ER -