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Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis.
Intern Med. 2018 Dec 01; 57(23):3479-3483.IM

Abstract

A 70-year-old man with prior Raynaud's phenomena developed hypertension and renal insufficiency. Raynaud's phenomena, finger skin thickening, interstitial lung disease, and positive anticentromere antibody findings indicated systemic sclerosis (SSc). Based on the presence of SSc, severe hypertension with rapidly progressive renal failure, and proliferative and obliterative arteriolar vasculopathy, scleroderma renal crisis (SRC) was diagnosed. Despite good blood pressure control with antihypertensive drugs, hemodialysis was initiated and could not be withdrawn owing to unimproved renal dysfunction. Although SRC in anticentromere antibody-positive limited cutaneous SSc is extremely rare, some patients may develop SRC, and their renal prognosis may be poor.

Authors+Show Affiliations

Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan. Department IV, Internal Medicine, Tokyo Women's Medical University, Japan.Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan.Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan.Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan. Department IV, Internal Medicine, Tokyo Women's Medical University, Japan.Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan. Department IV, Internal Medicine, Tokyo Women's Medical University, Japan.Division of Nephrology, Department of Medicine, Tokyo Metropolitan Komagome Hospital, Japan.Department IV, Internal Medicine, Tokyo Women's Medical University, Japan.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

30101908

Citation

Ubukata, Masamitsu, et al. "Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis." Internal Medicine (Tokyo, Japan), vol. 57, no. 23, 2018, pp. 3479-3483.
Ubukata M, Mitsuhashi A, Nishizawa Y, et al. Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis. Intern Med. 2018;57(23):3479-3483.
Ubukata, M., Mitsuhashi, A., Nishizawa, Y., Fujii, T., Hara, M., Ohta, A., & Nitta, K. (2018). Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis. Internal Medicine (Tokyo, Japan), 57(23), 3479-3483. https://doi.org/10.2169/internalmedicine.0980-18
Ubukata M, et al. Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis. Intern Med. 2018 Dec 1;57(23):3479-3483. PubMed PMID: 30101908.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anticentromere Antibody-positive Scleroderma Renal Crisis Requiring Dialysis. AU - Ubukata,Masamitsu, AU - Mitsuhashi,Atsushi, AU - Nishizawa,Yuki, AU - Fujii,Teruhiro, AU - Hara,Masaki, AU - Ohta,Akihito, AU - Nitta,Kosaku, Y1 - 2018/08/10/ PY - 2018/8/14/pubmed PY - 2019/2/23/medline PY - 2018/8/14/entrez KW - anticentromere antibody KW - scleroderma renal crisis KW - systemic sclerosis SP - 3479 EP - 3483 JF - Internal medicine (Tokyo, Japan) JO - Intern. Med. VL - 57 IS - 23 N2 - A 70-year-old man with prior Raynaud's phenomena developed hypertension and renal insufficiency. Raynaud's phenomena, finger skin thickening, interstitial lung disease, and positive anticentromere antibody findings indicated systemic sclerosis (SSc). Based on the presence of SSc, severe hypertension with rapidly progressive renal failure, and proliferative and obliterative arteriolar vasculopathy, scleroderma renal crisis (SRC) was diagnosed. Despite good blood pressure control with antihypertensive drugs, hemodialysis was initiated and could not be withdrawn owing to unimproved renal dysfunction. Although SRC in anticentromere antibody-positive limited cutaneous SSc is extremely rare, some patients may develop SRC, and their renal prognosis may be poor. SN - 1349-7235 UR - https://www.unboundmedicine.com/medline/citation/30101908/Anticentromere_Antibody_positive_Scleroderma_Renal_Crisis_Requiring_Dialysis_ L2 - https://dx.doi.org/10.2169/internalmedicine.0980-18 DB - PRIME DP - Unbound Medicine ER -