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The Role of Advanced Glycation End Products in Diabetic Vascular Complications.

Abstract

In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.

Authors+Show Affiliations

Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea.Department of Endocrinology and Metabolism, Kyung Hee University School of Medicine, Seoul, Korea. ycell00@gmail.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

30112876

Citation

Rhee, Sang Youl, and Young Seol Kim. "The Role of Advanced Glycation End Products in Diabetic Vascular Complications." Diabetes & Metabolism Journal, 2018.
Rhee SY, Kim YS. The Role of Advanced Glycation End Products in Diabetic Vascular Complications. Diabetes Metab J. 2018.
Rhee, S. Y., & Kim, Y. S. (2018). The Role of Advanced Glycation End Products in Diabetic Vascular Complications. Diabetes & Metabolism Journal.
Rhee SY, Kim YS. The Role of Advanced Glycation End Products in Diabetic Vascular Complications. Diabetes Metab J. 2018 May 31;. PubMed PMID: 30112876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The Role of Advanced Glycation End Products in Diabetic Vascular Complications. AU - Rhee,Sang Youl, AU - Kim,Young Seol, Y1 - 2018/05/31/ PY - 2017/12/27/received PY - 2018/03/29/accepted PY - 2018/8/17/entrez PY - 2018/8/17/pubmed PY - 2018/8/17/medline KW - Diabetes complications KW - Glycation end products, advanced KW - Receptor for advanced glycation end products SP - EP - JF - Diabetes & metabolism journal JO - Diabetes Metab J N2 - In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications. SN - 2233-6079 UR - https://www.unboundmedicine.com/medline/citation/30112876/The_Role_of_Advanced_Glycation_End_Products_in_Diabetic_Vascular_Complications_ DB - PRIME DP - Unbound Medicine ER -
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