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Histocompatibility antigens (HLA) in rheumatic diseases in Iran.
J Rheumatol Suppl. 1977; 3:36-8.JR

Abstract

One hundred and sixty-six patients with different forms of rheumatic diseases were tissue typed for 26 antigens of the A and B locus of the HLA system, using a modified KN cytotoxicity test. Among 25 patients with confirmed ankylosing spondylitis, 23 had HLA B27 (92 per cent), compared to 2.5 per cent in the normal controls. This confirms the strong association of HLA B27 with ankylosing spondylitis. Eight patients had doubtful AS, five of whom were positive for B27. In 21 patients with mechanical disorders of the spine no B27 was found. Thirty-six patients with osteoarthrosis of the knee joints did not show any significant relationship with any HLA antigens. Twenty-one patients with systemic lupus erythematosus showed an increase of HLA B13 and B17.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

301191

Citation

Davatchi, F, et al. "Histocompatibility Antigens (HLA) in Rheumatic Diseases in Iran." The Journal of Rheumatology. Supplement, vol. 3, 1977, pp. 36-8.
Davatchi F, Nikbin B, Ala F. Histocompatibility antigens (HLA) in rheumatic diseases in Iran. J Rheumatol Suppl. 1977;3:36-8.
Davatchi, F., Nikbin, B., & Ala, F. (1977). Histocompatibility antigens (HLA) in rheumatic diseases in Iran. The Journal of Rheumatology. Supplement, 3, 36-8.
Davatchi F, Nikbin B, Ala F. Histocompatibility Antigens (HLA) in Rheumatic Diseases in Iran. J Rheumatol Suppl. 1977;3:36-8. PubMed PMID: 301191.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Histocompatibility antigens (HLA) in rheumatic diseases in Iran. AU - Davatchi,F, AU - Nikbin,B, AU - Ala,F, PY - 1977/1/1/pubmed PY - 1977/1/1/medline PY - 1977/1/1/entrez SP - 36 EP - 8 JF - The Journal of rheumatology. Supplement JO - J Rheumatol Suppl VL - 3 N2 - One hundred and sixty-six patients with different forms of rheumatic diseases were tissue typed for 26 antigens of the A and B locus of the HLA system, using a modified KN cytotoxicity test. Among 25 patients with confirmed ankylosing spondylitis, 23 had HLA B27 (92 per cent), compared to 2.5 per cent in the normal controls. This confirms the strong association of HLA B27 with ankylosing spondylitis. Eight patients had doubtful AS, five of whom were positive for B27. In 21 patients with mechanical disorders of the spine no B27 was found. Thirty-six patients with osteoarthrosis of the knee joints did not show any significant relationship with any HLA antigens. Twenty-one patients with systemic lupus erythematosus showed an increase of HLA B13 and B17. SN - 0380-0903 UR - https://www.unboundmedicine.com/medline/citation/301191/Histocompatibility_antigens__HLA__in_rheumatic_diseases_in_Iran_ L2 - https://antibodies.cancer.gov/detail/CPTC-HLA-DPB1-2 DB - PRIME DP - Unbound Medicine ER -