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Prevalence of goitre and hypothyroidism in Southern Tanzania: effect of iodised oil on thyroid hormone deficiency.
J Epidemiol Community Health 1986; 40(1):86-91JE

Abstract

In the Southern Highlands of Tanzania the prevalence of endemic goitre due to iodine deficiency is in the range of 90% and hypothyroidism in the range of 50% of schoolchildren. The present study confirms these data and documents the beneficial effect of Lipiodol injections on thyroid function in children around the age of puberty compared with untreated children from the same villages. On the other hand, a decrease in the prevalence of goitre could not be shown. A beneficial effect is shown for infants of mothers who received iodine during pregnancy. It seems that this form of supplementation is sufficient for breast fed children for more than three years, even when a second child has been delivered in the meantime. In contrast, older siblings of these babies may become hypothyroid when breast feeding is stopped. The determination of thyroid autoantibodies in iodine treated and untreated children and in young adults showed no increasing prevalence of positive findings thus excluding iodine induced chronic thyroiditis at least in the young target population.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

3011945

Citation

Wächter, W, et al. "Prevalence of Goitre and Hypothyroidism in Southern Tanzania: Effect of Iodised Oil On Thyroid Hormone Deficiency." Journal of Epidemiology and Community Health, vol. 40, no. 1, 1986, pp. 86-91.
Wächter W, Mvungi M, König A, et al. Prevalence of goitre and hypothyroidism in Southern Tanzania: effect of iodised oil on thyroid hormone deficiency. J Epidemiol Community Health. 1986;40(1):86-91.
Wächter, W., Mvungi, M., König, A., Pickardt, C. R., & Scriba, P. C. (1986). Prevalence of goitre and hypothyroidism in Southern Tanzania: effect of iodised oil on thyroid hormone deficiency. Journal of Epidemiology and Community Health, 40(1), pp. 86-91.
Wächter W, et al. Prevalence of Goitre and Hypothyroidism in Southern Tanzania: Effect of Iodised Oil On Thyroid Hormone Deficiency. J Epidemiol Community Health. 1986;40(1):86-91. PubMed PMID: 3011945.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of goitre and hypothyroidism in Southern Tanzania: effect of iodised oil on thyroid hormone deficiency. AU - Wächter,W, AU - Mvungi,M, AU - König,A, AU - Pickardt,C R, AU - Scriba,P C, PY - 1986/3/1/pubmed PY - 1986/3/1/medline PY - 1986/3/1/entrez SP - 86 EP - 91 JF - Journal of epidemiology and community health JO - J Epidemiol Community Health VL - 40 IS - 1 N2 - In the Southern Highlands of Tanzania the prevalence of endemic goitre due to iodine deficiency is in the range of 90% and hypothyroidism in the range of 50% of schoolchildren. The present study confirms these data and documents the beneficial effect of Lipiodol injections on thyroid function in children around the age of puberty compared with untreated children from the same villages. On the other hand, a decrease in the prevalence of goitre could not be shown. A beneficial effect is shown for infants of mothers who received iodine during pregnancy. It seems that this form of supplementation is sufficient for breast fed children for more than three years, even when a second child has been delivered in the meantime. In contrast, older siblings of these babies may become hypothyroid when breast feeding is stopped. The determination of thyroid autoantibodies in iodine treated and untreated children and in young adults showed no increasing prevalence of positive findings thus excluding iodine induced chronic thyroiditis at least in the young target population. SN - 0143-005X UR - https://www.unboundmedicine.com/medline/citation/3011945/Prevalence_of_goitre_and_hypothyroidism_in_Southern_Tanzania:_effect_of_iodised_oil_on_thyroid_hormone_deficiency_ L2 - http://jech.bmj.com/cgi/pmidlookup?view=long&pmid=3011945 DB - PRIME DP - Unbound Medicine ER -