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HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant.
Dermatol Online J. 2018 05 15; 24(5)DO

Abstract

A 24-year-old man with untreated human immunodeficiency virus (HIV) infection consulted our outreach clinic owing to the development of numerous asymptomatic nodules on his palms and fingers. Histopathologic evaluation revealed leukocytoclastic vasculitis and prominent fibrosis with a neutrophilic infiltrate consistent with erythema elevatum diutinum (EED). We referred the patient for initiation of antiretroviral therapy and started him on dapsone. The pathogenesis of EED is not completely understood, but it has been associated with numerous systemic conditions that may be infectious, inflammatory, or neoplastic. Only recently has EED been recognized as a defined reactive dermatosis of HIV. We present an exemplary case of HIV-associated EED and review the differential diagnosis, highlighting clinical features of EED that appear to be more frequently encountered in the HIV-infected population.

Authors+Show Affiliations

Medstar Georgetown University Hospital, Washington, District of Columbia. mcardis0@gmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

30142732

Citation

Cardis, Michael A., et al. "HIV-associated Erythema Elevatum Diutinum: a Case Report and Review of a Clinically Distinct Variant." Dermatology Online Journal, vol. 24, no. 5, 2018.
Cardis MA, Sowash MG, Mosojane KI, et al. HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant. Dermatol Online J. 2018;24(5).
Cardis, M. A., Sowash, M. G., Mosojane, K. I., Kovarik, C., & Williams, V. (2018). HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant. Dermatology Online Journal, 24(5).
Cardis MA, et al. HIV-associated Erythema Elevatum Diutinum: a Case Report and Review of a Clinically Distinct Variant. Dermatol Online J. 2018 05 15;24(5) PubMed PMID: 30142732.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HIV-associated erythema elevatum diutinum: a case report and review of a clinically distinct variant. AU - Cardis,Michael A, AU - Sowash,Madeleine G, AU - Mosojane,Karen Itumeleng, AU - Kovarik,Carrie, AU - Williams,Victoria, Y1 - 2018/05/15/ PY - 2018/07/24/received PY - 2018/07/24/accepted PY - 2018/8/26/entrez PY - 2018/8/26/pubmed PY - 2018/12/15/medline JF - Dermatology online journal JO - Dermatol Online J VL - 24 IS - 5 N2 - A 24-year-old man with untreated human immunodeficiency virus (HIV) infection consulted our outreach clinic owing to the development of numerous asymptomatic nodules on his palms and fingers. Histopathologic evaluation revealed leukocytoclastic vasculitis and prominent fibrosis with a neutrophilic infiltrate consistent with erythema elevatum diutinum (EED). We referred the patient for initiation of antiretroviral therapy and started him on dapsone. The pathogenesis of EED is not completely understood, but it has been associated with numerous systemic conditions that may be infectious, inflammatory, or neoplastic. Only recently has EED been recognized as a defined reactive dermatosis of HIV. We present an exemplary case of HIV-associated EED and review the differential diagnosis, highlighting clinical features of EED that appear to be more frequently encountered in the HIV-infected population. SN - 1087-2108 UR - https://www.unboundmedicine.com/medline/citation/30142732/HIV_associated_erythema_elevatum_diutinum:_a_case_report_and_review_of_a_clinically_distinct_variant_ L2 - http://escholarship.org/uc/item/38c4c9g3 DB - PRIME DP - Unbound Medicine ER -